MIR938 Gene (RNA Gene)

MicroRNA 938

GC10M030087
GIFtS:
16
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR938 Gene

Subcategory (RNA class) for MIR938 Gene

miRNA

Quality Score for this RNA gene is

14

Aliases for MIR938 Gene

  • MicroRNA 938 2 3 5
  • MIMAT0004981 53
  • Hsa-Mir-938 3
  • MI0005760 53
  • MIRN938 3
  • RF00964 174
  • MIR938 2

External Ids for MIR938 Gene

Previous HGNC Symbols for MIR938 Gene

  • MIRN938

Previous GeneCards Identifiers for MIR938 Gene

  • GC10M029933
  • GC10M029629
  • GC10M030029
  • GC10M030083
  • GC10M029630
  • GC10M029718
  • GC10M029721
  • GC10M029763
  • GC10M029845
  • GC10M029929
  • GC10M029979

Summaries for MIR938 Gene

Entrez Gene Summary for MIR938 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR938 Gene

MIR938 (MicroRNA 938) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR938 include Type 1 Diabetes Mellitus 10.

Rfam classification for MIR938 Gene

Additional gene information for MIR938 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR938 Gene

Genomics for MIR938 Gene

GeneHancer (GH) Regulatory Elements for MIR938 Gene

Promoters and enhancers for MIR938 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH10J029603 Enhancer 0.6 Ensembl ENCODE dbSUPER 750.6 -1.4 -1354 3.4 ZNF121 MIR938 RNU6-908P SVIL-AS1 piR-31534-061 SVIL lnc-JCAD-7
GH10J029605 Enhancer 0.4 Ensembl dbSUPER 750.6 +0.9 946 0.4 SCRT2 MIR938 MIR604 RNU6-908P SVIL SVIL-AS1 ENSG00000212411 lnc-JCAD-7
GH10J029582 Enhancer 1.5 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +16.1 16054 10.2 CTCF SREBF1 TCF7L2 RAD21 MNT ZNF280D ZNF384 NCOA3 ZSCAN21 ZNF687 SVIL MIR604 CKS1BP2 RNU6-908P SVIL-AS1 ENSG00000212411 MIR938 lnc-JCAD-7
GH10J029597 Enhancer 0.5 ENCODE dbSUPER 0.6 +3.1 3084 3.3 ZNF121 SCRT2 MIR604 RNU6-908P SVIL SVIL-AS1 MIR938 ENSG00000212411 lnc-JCAD-7
GH10J029611 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.4 -10.2 -10155 2.2 NFIB PRDM10 CEBPB POLR2A NFIC KLF1 piR-31534-061 SVIL MIR604 MIR938 lnc-JCAD-7
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR938 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR938 Gene

Genomic Locations for MIR938 Gene
chr10:29,602,264-29,602,346
(GRCh38/hg38)
Size:
83 bases
Orientation:
Minus strand
chr10:29,891,193-29,891,275
(GRCh37/hg19)
Size:
83 bases
Orientation:
Minus strand

Genomic View for MIR938 Gene

Genes around MIR938 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR938 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR938 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR938 Gene

Proteins for MIR938 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR938 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR938 Gene

Domains & Families for MIR938 Gene

Gene Families for MIR938 Gene

HGNC:
genes like me logo Genes that share domains with MIR938: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR938 Gene

Function for MIR938 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR938 Gene

Localization for MIR938 Gene

Gene Ontology (GO) - Cellular Components for MIR938 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016442 RISC complex IEA --
genes like me logo Genes that share ontologies with MIR938: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR938 Gene

Pathways & Interactions for MIR938 Gene

PathCards logo

SuperPathways for MIR938 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR938 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR938: view

No data available for Pathways by source and SIGNOR curated interactions for MIR938 Gene

Drugs & Compounds for MIR938 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR938 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR938 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(1) Rfam transcripts :
(2) miRBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR938 Gene

No ASD Table

Relevant External Links for MIR938 Gene

GeneLoc Exon Structure for
MIR938
ECgene alternative splicing isoforms for
MIR938

Expression for MIR938 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR938 Gene

mRNA expression in normal human tissues for MIR938 Gene
mRNA expression by GTEx for MIR938 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR938 Gene:

MIR938
genes like me logo Genes that share expression patterns with MIR938: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR938 Gene

Orthologs for MIR938 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR938 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-938 33
  • 98 (a)
 OneToOne
Species where no ortholog for MIR938 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR938 Gene

ENSEMBL:
Gene Tree for MIR938 (if available)
TreeFam:
Gene Tree for MIR938 (if available)

Paralogs for MIR938 Gene

No data available for Paralogs for MIR938 Gene

Variants for MIR938 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for MIR938 Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
rs1002602309 -- 29,603,555(-) T/C upstream_transcript_variant
rs1002634713 -- 29,603,788(-) T/C upstream_transcript_variant
rs1003635410 -- 29,602,549(-) T/C upstream_transcript_variant
rs1003816153 -- 29,602,819(-) C/A upstream_transcript_variant
rs1004061619 -- 29,603,185(-) C/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR938 Gene

Variant ID Type Subtype PubMed ID
nsv1129323 OTHER inversion 24896259
nsv831819 CNV loss 17160897

Additional Variant Information for MIR938 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR938

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR938 Gene

Disorders for MIR938 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR938 Gene - From: DISEASES

Disorder Aliases PubMed IDs
type 1 diabetes mellitus 10
  • diabetes mellitus, insulin-dependent, 10
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR938

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MIR938: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR938 Gene

Publications for MIR938 Gene

  1. Association of miR-938G>A Polymorphisms with Primary Ovarian Insufficiency (POI)-Related Gene Expression. (PMID: 28604625) Cho SH … Kim NK (International journal of molecular sciences 2017) 3 56
  2. miR-938 promotes colorectal cancer cell proliferation via targeting tumor suppressor PHLPP2. (PMID: 28433657) Li CF … Li DD (European journal of pharmacology 2017) 3 56
  3. Genetic polymorphisms of IL17A and pri-microRNA-938, targeting IL17A 3'-UTR, influence susceptibility to gastric cancer. (PMID: 22537748) Arisawa T … Shibata T (Human immunology 2012) 3 56
  4. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui WO … Fire A (Cancer research 2007) 3 56
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

ExternalLinks

View latest publications for MIR938 gene in Mastermind

Products for MIR938 Gene

Sources for MIR938 Gene