microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR938 Gene

Data sources for MIR938 Gene:

RNA type for MIR938 Gene

miRNA

Aliases for MIR938 Gene

External Ids for MIR938 Gene

Previous HGNC Symbols for MIR938 Gene

  • MIRN938

Previous GeneCards Identifiers for MIR938 Gene

  • GC10M029933
  • GC10M029629
  • GC10M030029
  • GC10M030083
  • GC10M030087
  • GC10M030283
  • GC10M029630
  • GC10M029718
  • GC10M029721
  • GC10M029763
  • GC10M029845
  • GC10M029929
  • GC10M029979
  • GC10M030483
  • GC10M030684

Summaries for MIR938 Gene

Entrez Gene Summary for MIR938 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR938 Gene

MIR938 (MicroRNA 938) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR938 include Type 1 Diabetes Mellitus 10.

Rfam classification for MIR938 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR938 Gene

Genomics for MIR938 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR938 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10J029602 Enhancer 0.6 Ensembl ENCODE dbSUPER 250.7 -1.8 -1754 2.6 ZNF121 MIR938 RNU6-908P SVIL-AS1 piR-31534-061 SVIL lnc-JCAD-7 LYZL1
GH10J029601 Enhancer 0.4 Ensembl dbSUPER 250.7 +0.6 645 0.2 SCRT2 MIR938 ENSG00000212411 SVIL lnc-JCAD-7 LYZL1
GH10J029603 Enhancer 0.3 Ensembl dbSUPER 250.7 -0.2 -155 0.2 MIR938 piR-31534-061 SVIL lnc-JCAD-7 LYZL1
GH10J029596 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.7 +4.2 4247 6.2 ATF2 MNT FOS EP300 ZNF121 SCRT2 MIR604 RNU6-908P SVIL SVIL-AS1 MIR938 ENSG00000212411 lnc-JCAD-7 LYZL1
GH10J029582 Enhancer 1.4 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 0.4 +15.4 15402 8.9 ZNF654 ZNF580 ZNF10 CTCF TRIM22 HES1 CTBP1 RAD21 CUX1 SMC3 SVIL MIR604 RNU6-908P SVIL-AS1 ENSG00000212411 MIR938 lnc-JCAD-7 LYZL1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR938 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR938 Gene

Latest Assembly
chr10:29,602,264-29,602,346
(GRCh38/hg38)
Size:
83 bases
Orientation:
Minus strand

Previous Assembly
chr10:29,891,193-29,891,275
(GRCh37/hg19 by Entrez Gene)
Size:
83 bases
Orientation:
Minus strand

chr10:29,891,193-29,891,275
(GRCh37/hg19 by Ensembl)
Size:
83 bases
Orientation:
Minus strand

Genomic View for MIR938 Gene

Genes around MIR938 on UCSC Golden Path with GeneCards custom track
MIR938 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR938 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR938 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR938 Gene

Proteins for MIR938 Gene

Post-translational modifications for MIR938 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR938 Gene

Domains & Families for MIR938 Gene

Gene Families for MIR938 Gene

HGNC:
genes like me logo Genes that share domains with MIR938: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR938 Gene

Function for MIR938 Gene

Phenotypes From GWAS Catalog for MIR938 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR938 Gene

Localization for MIR938 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR938 Gene

Pathways & Interactions for MIR938 Gene

PathCards logo

SuperPathways for MIR938 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR938 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR938: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR938 Gene

Drugs & Compounds for MIR938 Gene

No Compound Related Data Available

Transcripts for MIR938 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR938 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS00006DA7A7_9606 pre_miRNA 83 4

RefSeq: NR_030634,

Ensembl: ENST00000401216 (view in UCSC) ,

miRBase: MI0005760,

Rfam: RF00964,

URS000075DF80_9606 miRNA 22 2

RefSeq: NR_030634,

miRBase: MIMAT0004981,

URS0001BBF3F4_9606 pre_miRNA 83 1

Rfam: RF00964,

MIR938 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR938 Gene

No ASD Table

Relevant External Links for MIR938 Gene

GeneLoc Exon Structure for
MIR938

No data available for mRNA/cDNA for MIR938 Gene

Expression for MIR938 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR938 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR938

genes like me logo Genes that share expression patterns with MIR938: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR938 Gene

Orthologs for MIR938 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR938 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-938 30
  • 98 (a)
OneToOne
Species where no ortholog for MIR938 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR938 Gene

ENSEMBL:
Gene Tree for MIR938 (if available)
TreeFam:
Gene Tree for MIR938 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR938

Paralogs for MIR938 Gene

No data available for Paralogs for MIR938 Gene

Variants for MIR938 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR938 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR938 Gene

Variant ID Type Subtype PubMed ID
nsv1129323 OTHER inversion 24896259
nsv831819 CNV loss 17160897

Additional Variant Information for MIR938 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR938
Leiden Open Variation Database (LOVD)
MIR938

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR938 Gene

Disorders for MIR938 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR938 Gene - From: COP

Disorder Aliases PubMed IDs
type 1 diabetes mellitus 10
  • t1d10
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR938

genes like me logo Genes that share disorders with MIR938: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR938 Gene

Publications for MIR938 Gene

  1. rs12416605:C>T in MIR938 associates with gastric cancer through affecting the regulation of the CXCL12 chemokine gene. (PMID: 31273931) Torruella-Loran I … EPIC gastric cancer working group (Molecular genetics & genomic medicine 2019) 3
  2. miR-938 promotes colorectal cancer cell proliferation via targeting tumor suppressor PHLPP2. (PMID: 28433657) Li CF … Li DD (European journal of pharmacology 2017) 3
  3. Association of miR-938G>A Polymorphisms with Primary Ovarian Insufficiency (POI)-Related Gene Expression. (PMID: 28604625) Cho SH … Kim NK (International journal of molecular sciences 2017) 3
  4. Genetic polymorphisms of IL17A and pri-microRNA-938, targeting IL17A 3'-UTR, influence susceptibility to gastric cancer. (PMID: 22537748) Arisawa T … Shibata T (Human immunology 2012) 3
  5. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui WO … Fire A (Cancer research 2007) 3

Products for MIR938 Gene

Sources for MIR938 Gene