microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR936 Gene

Subcategory (RNA class) for MIR936 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR936 Gene

  • MicroRNA 936 2 3 5
  • Hsa-MiR-936 166 177
  • MIMAT0004979 51
  • Hsa-Mir-936 3
  • MI0005758 51
  • MIRN936 3
  • RF01002 172
  • MIR936 2

External Ids for MIR936 Gene

Previous HGNC Symbols for MIR936 Gene

  • MIRN936

Previous GeneCards Identifiers for MIR936 Gene

  • GC10M105799

Summaries for MIR936 Gene

Entrez Gene Summary for MIR936 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR936 Gene

MIR936 (MicroRNA 936) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Collagen chain trimerization and Degradation of the extracellular matrix.

Rfam classification for MIR936 Gene

Additional gene information for MIR936 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR936 Gene

Genomics for MIR936 Gene

GeneHancer (GH) Regulatory Elements for MIR936 Gene

Promoters and enhancers for MIR936 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR936 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR936 Gene

Genomic Locations for MIR936 Gene
chr10:104,048,089-104,048,186
(GRCh38/hg38)
Size:
98 bases
Orientation:
Minus strand
chr10:105,807,847-105,807,944
(GRCh37/hg19)
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR936 Gene

Genes around MIR936 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR936 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR936 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR936 Gene

Proteins for MIR936 Gene

Post-translational modifications for MIR936 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR936 Gene

Domains & Families for MIR936 Gene

Gene Families for MIR936 Gene

HGNC:
genes like me logo Genes that share domains with MIR936: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR936 Gene

Function for MIR936 Gene

Phenotypes From GWAS Catalog for MIR936 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR936 Gene

Localization for MIR936 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR936 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR936 Gene

Pathways & Interactions for MIR936 Gene

No data available for Interacting Proteins and SIGNOR curated interactions for MIR936 Gene

Drugs & Compounds for MIR936 Gene

No Compound Related Data Available

Transcripts for MIR936 Gene

mRNA/cDNA for MIR936 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 LncBase transcripts :
1 Rfam transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR936 Gene

No ASD Table

Relevant External Links for MIR936 Gene

GeneLoc Exon Structure for
MIR936

Expression for MIR936 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR936 Gene

mRNA differential expression in normal tissues according to GTEx for MIR936 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x26.0) and Skin - Sun Exposed (Lower leg) (x20.1).
genes like me logo Genes that share expression patterns with MIR936: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR936 Gene

Orthologs for MIR936 Gene

Evolution for MIR936 Gene

ENSEMBL:
Gene Tree for MIR936 (if available)
TreeFam:
Gene Tree for MIR936 (if available)

No data available for Orthologs for MIR936 Gene

Paralogs for MIR936 Gene

No data available for Paralogs for MIR936 Gene

Variants for MIR936 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR936 Gene

SNP ID Clinical significance and condition Chr 10 pos Variation AA Info Type
728158 Benign: not provided 104,048,097(-) A/C NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
rs1554848576 Likely Pathogenic: not provided 104,048,097(-) AGCAGGACCTG/CAA SPLICE_ACCEPTOR_VARIANT,NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for MIR936 Gene

Additional Variant Information for MIR936 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR936

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR936 Gene

Disorders for MIR936 Gene

Additional Disease Information for MIR936

No disorders were found for MIR936 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR936 Gene

Publications for MIR936 Gene

  1. Patterns of known and novel small RNAs in human cervical cancer. (PMID: 17616659) Lui WO … Fire A (Cancer research 2007) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR936 Gene

Sources for MIR936 Gene