microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR935 Gene

Subcategory (RNA class) for MIR935 Gene

miRNA

Quality Score for this RNA gene is

16

Aliases for MIR935 Gene

  • MicroRNA 935 2 3 5
  • Hsa-MiR-935 168 179
  • MIMAT0004978 53
  • Hsa-Mir-935 3
  • MI0005757 53
  • Mir-935 3
  • MIRN935 3
  • MIR935 2

External Ids for MIR935 Gene

Previous HGNC Symbols for MIR935 Gene

  • MIRN935

Previous GeneCards Identifiers for MIR935 Gene

  • GC19P059179
  • GC19P054485
  • GC19P053984
  • GC19P054066
  • GC19P054068
  • GC19P053986
  • GC19P054017
  • GC19P054040

Summaries for MIR935 Gene

Entrez Gene Summary for MIR935 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR935 Gene

MIR935 (MicroRNA 935) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Phase 0 - rapid depolarisation and Developmental Biology.

Additional gene information for MIR935 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR935 Gene

Genomics for MIR935 Gene

GeneHancer (GH) Regulatory Elements for MIR935 Gene

Promoters and enhancers for MIR935 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR935 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR935 Gene

Genomic Locations for MIR935 Gene
chr19:53,982,307-53,982,397
(GRCh38/hg38)
Size:
91 bases
Orientation:
Plus strand
chr19:54,485,561-54,485,651
(GRCh37/hg19)
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR935 Gene

Genes around MIR935 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR935 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR935 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR935 Gene

Proteins for MIR935 Gene

Post-translational modifications for MIR935 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR935 Gene

Domains & Families for MIR935 Gene

Gene Families for MIR935 Gene

HGNC:
genes like me logo Genes that share domains with MIR935: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR935 Gene

Function for MIR935 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR935 Gene

Localization for MIR935 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR935 Gene

Pathways & Interactions for MIR935 Gene

genes like me logo Genes that share pathways with MIR935: view

Gene Ontology (GO) - Biological Process for MIR935 Gene

None

No data available for SIGNOR curated interactions for MIR935 Gene

Drugs & Compounds for MIR935 Gene

No Compound Related Data Available

Transcripts for MIR935 Gene

mRNA/cDNA for MIR935 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :
(1) TarBase transcripts :
(3) ENA transcripts :
(1) LncBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR935 Gene

No ASD Table

Relevant External Links for MIR935 Gene

GeneLoc Exon Structure for
MIR935
ECgene alternative splicing isoforms for
MIR935

Expression for MIR935 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR935 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR935 Gene:

MIR935
genes like me logo Genes that share expression patterns with MIR935: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR935 Gene

Orthologs for MIR935 Gene

Evolution for MIR935 Gene

ENSEMBL:
Gene Tree for MIR935 (if available)
TreeFam:
Gene Tree for MIR935 (if available)

No data available for Orthologs for MIR935 Gene

Paralogs for MIR935 Gene

No data available for Paralogs for MIR935 Gene

Variants for MIR935 Gene

Sequence variations from dbSNP and Humsavar for MIR935 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1001212732 -- 53,981,614(+) T/A upstream_transcript_variant
rs1002247030 -- 53,980,896(+) A/G upstream_transcript_variant
rs1002276725 -- 53,981,117(+) T/G upstream_transcript_variant
rs1002372288 -- 53,981,907(+) C/T upstream_transcript_variant
rs1002445762 -- 53,981,622(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR935 Gene

Variant ID Type Subtype PubMed ID
dgv1815n106 CNV deletion 24896259
esv2718812 CNV deletion 23290073
nsv1063127 CNV gain 25217958
nsv458782 CNV gain 19166990
nsv580110 CNV gain 21841781
nsv580111 CNV loss 21841781
nsv833876 CNV loss 17160897
nsv833877 CNV loss 17160897
nsv953612 CNV deletion 24416366

Additional Variant Information for MIR935 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR935

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR935 Gene

Disorders for MIR935 Gene

Additional Disease Information for MIR935

No disorders were found for MIR935 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR935 Gene

Publications for MIR935 Gene

  1. miR-935 promotes gastric cancer cell proliferation by targeting SOX7. (PMID: 27044823) Yang M … Chen L (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 2 3 56
  2. miR-935 suppresses gastric signet ring cell carcinoma tumorigenesis by targeting Notch1 expression. (PMID: 26742429) Yan C … Zhou L (Biochemical and biophysical research communications 2016) 2 3 56
  3. INT-HA induces M2-like macrophage differentiation of human monocytes via TLR4-miR-935 pathway. (PMID: 30341559) Zhang B … Gao F (Cancer immunology, immunotherapy : CII 2019) 3 56
  4. Upregulation of MicroRNA-935 Promotes the Malignant Behaviors of Pancreatic Carcinoma PANC-1 Cells via Targeting Inositol Polyphosphate 4-Phosphatase Type I Gene (INPP4A). (PMID: 27733216) Wang C … Zuo X (Oncology research 2017) 3 56
  5. miR-935 Promotes Liver Cancer Cell Proliferation and Migration by Targeting SOX7. (PMID: 27697092) Liu X … Kan Q (Oncology research 2017) 3 56

Products for MIR935 Gene

Sources for MIR935 Gene