Aliases for MIR92A2 Gene
Subcategory (RNA class) for MIR92A2 Gene
miRNA
Quality Score for this RNA gene is
3
Aliases for MIR92A2 Gene
External Ids for MIR92A2 Gene
- HGNC: 31644
- Entrez Gene: 407049
- Ensembl: ENSG00000284538
- miRBase: hsa-mir-92a-2
ORGUL Members for MIR92A2 Gene
Previous HGNC Symbols for MIR92A2 Gene
- MIRN92-2
- MIRN92A2
Previous GeneCards Identifiers for MIR92A2 Gene
- GC0XM133151
- GC0XM133158
- GC0XM133305
- GC0XM133310
- GC0XM133314
- GC0XM133318
- GC0XM133323
- GC0XM133327
- GC0XM133331
- GC0XM133335
- GC0XM133347
- GC0XM133372
- GC0XM134171
- GC0XM134176
- GC0XM134181
- GC0XM134188
- GC0XM134194
Summaries for MIR92A2 Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR92A2 Gene
MIR92A2 (MicroRNA 92a-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer and Parkinsons Disease Pathway.
Additional gene information for MIR92A2 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR92A2 Gene
Genomics for MIR92A2 Gene
Regulatory Element Products
Genomic Locations for MIR92A2 Gene
Genomic Locations for MIR92A2 Gene
- chrX:134,169,538-134,169,612
- (GRCh38/hg38)
- Size:
- 75 bases
- Orientation:
- Minus strand
- chrX:133,303,568-133,303,642
- (GRCh37/hg19)
Genomic View for MIR92A2 Gene
Genes around MIR92A2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq26.2 by Ensembl
- Xq26.2 by Entrez Gene
- Xq26.2 by HGNC
MIR92A2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MIR92A2 Gene
No data available for GeneHancer (GH) Regulatory Elements for MIR92A2 Gene
Proteins for MIR92A2 Gene
Post-translational modifications for MIR92A2 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MIR92A2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR92A2
- Origene Custom Protein Services for MIR92A2
- Search GeneTex for Proteins for MIR92A2
No data available for DME Specific Peptides for MIR92A2 Gene
Domains & Families for MIR92A2 Gene
Gene Families for MIR92A2 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR92A2 Gene
Function for MIR92A2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:1903231 | mRNA binding involved in posttranscriptional gene silencing | IMP | 20484043 |
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR92A2
-
- Search ViGene Biosciences for MIR92A2
CRISPR Products
- Browse CRISPR knockouts for MIR92A2
- Applied Biological Materials CRISPR for MIR92A2
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR92A2
Clone Products
- GenScript: Custom all cDNA clones Services for MIR92A2
- VectorBuilder custom plasmid, inducible vectors for MIR92A2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR92A2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR92A2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR92A2 Gene
Localization for MIR92A2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IDA | 26646931 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR92A2 Gene
Pathways & Interactions for MIR92A2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | MicroRNAs in cancer | ||
| 2 | Parkinsons Disease Pathway | ||
Pathways by source for MIR92A2 Gene
1 BioSystems pathway for MIR92A2 Gene
1 KEGG pathway for MIR92A2 Gene
Interacting Proteins for MIR92A2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001937 | NOT negative regulation of endothelial cell proliferation | IDA | 19460962 |
| GO:0002675 | positive regulation of acute inflammatory response | ISS | -- |
| GO:0008016 | regulation of heart contraction | ISS | -- |
| GO:0010628 | positive regulation of gene expression | IMP | 22267480 |
| GO:0010629 | negative regulation of gene expression | IMP | 20484043 |
No data available for SIGNOR curated interactions for MIR92A2 Gene
Transcripts for MIR92A2 Gene
mRNA/cDNA for MIR92A2 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR92A2
- Applied Biological Materials CRISPR for MIR92A2
-
Vectors and viruses for KO, Activation, Repression, and more
Inhibitory RNA Products
- Search ViGene Biosciences for MIR92A2
Clone Products
- GenScript: Custom all cDNA clones Services for MIR92A2
- VectorBuilder custom plasmid, inducible vectors for MIR92A2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR92A2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR92A2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR92A2 Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR92A2 Gene:
MIR92A2
No Expression Related Data Available
Primer Products
Gene Expression Assay Products
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR92A2 Gene
Orthologs for MIR92A2 Gene
No data available for Orthologs for MIR92A2 Gene
Paralogs for MIR92A2 Gene
No data available for Paralogs for MIR92A2 Gene
Variants for MIR92A2 Gene
| SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1003822325 | -- | 134,171,007(-) | T/C | upstream_transcript_variant | |
| rs1004871742 | -- | 134,171,563(-) | A/G | upstream_transcript_variant | |
| rs1004902717 | -- | 134,170,953(-) | A/G | upstream_transcript_variant | |
| rs1005828091 | -- | 134,169,983(-) | T/G | upstream_transcript_variant | |
| rs1007316405 | -- | 134,171,110(-) | G/A | upstream_transcript_variant |
Additional Variant Information for MIR92A2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR92A2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR92A2 Gene
Disorders for MIR92A2 Gene
Additional Disease Information for MIR92A2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for MIR92A2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR92A2 Gene
Publications for MIR92A2 Gene
- MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y … Liu P (Schizophrenia research 2010) 3 44 58
- Serum microRNA panel for early diagnosis of the onset of hepatocellular carcinoma. (PMID: 28079796) Zhang Y … Han L (Medicine 2017) 3 58
- Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7. (PMID: 28069547) Jiang X … Chen C (Gene 2017) 3 58
- CDKN2B-AS may indirectly regulate coronary artery disease-associated genes via targeting miR-92a. (PMID: 28760552) Cheng M … Li J (Gene 2017) 3 58
- Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
Products for MIR92A2 Gene
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- Browse Activity Assays
- Browse cDNA Clones
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- Custom Assay Services
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR92A2
- VectorBuilder custom plasmid, inducible vectors for MIR92A2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR92A2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR92A2
- Search GeneTex for Proteins for MIR92A2
- Search ViGene Biosciences for MIR92A2
Sources for MIR92A2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems