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Aliases for MIR92A1 Gene

Subcategory (RNA class) for MIR92A1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR92A1 Gene

  • MicroRNA 92a-1 2 3 5
  • MicroRNA 92-1 2 3
  • Putative MicroRNA 17 Host Gene Protein 3
  • Putative MicroRNA Host Gene 1 Protein 3
  • Hsa-Mir-92a-1 3
  • Hsa-Mir-92-1 3
  • MIRN92A-1 3
  • MiRNA92-1 3
  • Mir-92a-1 3
  • C13orf25 3
  • MIRN92-1 3
  • MIRN92A1 3
  • MIR17HG 3
  • MIR92-1 3
  • MIRHG1 3
  • MIRH1 3

External Ids for MIR92A1 Gene

Previous HGNC Symbols for MIR92A1 Gene

  • MIRN92-1
  • MIRN92A1

Previous GeneCards Identifiers for MIR92A1 Gene

  • GC13P090874
  • GC13P090882
  • GC13P092013
  • GC13P092022
  • GC13P092029
  • GC13P092037
  • GC13P092046
  • GC13P092056
  • GC13P092065
  • GC13P092075
  • GC13P092083
  • GC13P092096
  • GC13P092109
  • GC13P091355
  • GC13P091361
  • GC13P091369
  • GC13P091348
  • GC13P091366
  • GC13P091367

Summaries for MIR92A1 Gene

Entrez Gene Summary for MIR92A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR92A1 Gene

MIR92A1 (MicroRNA 92a-1) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are DNA Damage Response and MicroRNAs in cancer.

Additional gene information for MIR92A1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR92A1 Gene

Genomics for MIR92A1 Gene

GeneHancer (GH) Regulatory Elements for MIR92A1 Gene

Promoters and enhancers for MIR92A1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I091346 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 0.8 -2.3 -2281 4.8 PKNOX1 CLOCK FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 GLIS2 GC13P091372 GC13P091377 GC13P091384 GC13P091391 GC13P091394 GC13P091397 GC13P091399 GC13P091400 GC13P091401 MIR17
GH13I091398 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE 0.2 +47.2 47224 0.7 CLOCK SIN3A ZIC2 ZNF507 ZNF335 POLR2A RCOR1 PRDM10 ZNF214 EZH2 GPC5 MIR92A1
GH13I091372 Enhancer 0.7 ENCODE 0.3 +21.7 21688 0.2 FOXA2 TAF1 SAP130 MAX CEBPG RAD21 YY1 HNF4G RXRA HLF MIR92A1 GPC5
GH13I091359 Enhancer 0.3 ENCODE 0.4 +8.0 8008 0.1 ZNF384 MIR92A1 GPC5
GH13I091369 Enhancer 0.2 ENCODE 0.4 +18.3 18308 0.2 MIR92A1 GPC5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR92A1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR92A1 Gene

Genomic Locations for MIR92A1 Gene
chr13:91,351,314-91,351,391
(GRCh38/hg38)
Size:
78 bases
Orientation:
Plus strand
chr13:92,000,074-92,006,833
(GRCh37/hg19)

Genomic View for MIR92A1 Gene

Genes around MIR92A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR92A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR92A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR92A1 Gene

Proteins for MIR92A1 Gene

Post-translational modifications for MIR92A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR92A1 Gene

Domains & Families for MIR92A1 Gene

Gene Families for MIR92A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR92A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR92A1 Gene

Function for MIR92A1 Gene

Gene Ontology (GO) - Molecular Function for MIR92A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IMP 20484043
genes like me logo Genes that share ontologies with MIR92A1: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR92A1 Gene

Localization for MIR92A1 Gene

Gene Ontology (GO) - Cellular Components for MIR92A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
GO:0005737 cytoplasm IDA 25336585
genes like me logo Genes that share ontologies with MIR92A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR92A1 Gene

Pathways & Interactions for MIR92A1 Gene

genes like me logo Genes that share pathways with MIR92A1: view

Pathways by source for MIR92A1 Gene

1 KEGG pathway for MIR92A1 Gene

Interacting Proteins for MIR92A1 Gene

Gene Ontology (GO) - Biological Process for MIR92A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001937 NOT negative regulation of endothelial cell proliferation IDA 19460962
GO:0002675 positive regulation of acute inflammatory response ISS --
GO:0008016 regulation of heart contraction ISS --
GO:0010628 positive regulation of gene expression IMP 22267480
GO:0010629 negative regulation of gene expression IMP 20484043
genes like me logo Genes that share ontologies with MIR92A1: view

No data available for SIGNOR curated interactions for MIR92A1 Gene

Drugs & Compounds for MIR92A1 Gene

No Compound Related Data Available

Transcripts for MIR92A1 Gene

mRNA/cDNA for MIR92A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR92A1 Gene

No ASD Table

Relevant External Links for MIR92A1 Gene

GeneLoc Exon Structure for
MIR92A1
ECgene alternative splicing isoforms for
MIR92A1

Expression for MIR92A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR92A1 Gene:

MIR92A1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR92A1 Gene

Orthologs for MIR92A1 Gene

Evolution for MIR92A1 Gene

ENSEMBL:
Gene Tree for MIR92A1 (if available)
TreeFam:
Gene Tree for MIR92A1 (if available)

No data available for Orthologs for MIR92A1 Gene

Paralogs for MIR92A1 Gene

No data available for Paralogs for MIR92A1 Gene

Variants for MIR92A1 Gene

Sequence variations from dbSNP and Humsavar for MIR92A1 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1001980789 -- 91,351,489(+) G/A downstream_transcript_variant
rs1002349918 -- 91,351,188(+) T/C/G upstream_transcript_variant
rs1002944928 -- 91,349,535(+) G/A upstream_transcript_variant
rs1003385207 -- 91,349,835(+) A/G upstream_transcript_variant
rs1004434983 -- 91,349,440(+) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR92A1 Gene

Variant ID Type Subtype PubMed ID
nsv832679 CNV gain 17160897

Additional Variant Information for MIR92A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR92A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR92A1 Gene

Disorders for MIR92A1 Gene

Additional Disease Information for MIR92A1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR92A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR92A1 Gene

Publications for MIR92A1 Gene

  1. Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women. (PMID: 19950226) Kontorovich T … Friedman E (International journal of cancer 2010) 3 44 58
  2. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y … Liu P (Schizophrenia research 2010) 3 44 58
  3. Diagnostic Value of Serum hsa-mir-92a in Patients with Cervical Cancer. (PMID: 28182350) Kong Q … Kang X (Clinical laboratory 2017) 3 58
  4. Exosomal microRNA concentrations in colorectal cancer: A mathematical model. (PMID: 27993628) Lai X … Friedman A (Journal of theoretical biology 2017) 3 58
  5. Overexpression of miR-92a promotes the tumor growth of osteosarcoma by suppressing F-box and WD repeat-containing protein 7. (PMID: 28069547) Jiang X … Chen C (Gene 2017) 3 58

Products for MIR92A1 Gene

Sources for MIR92A1 Gene

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