microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR920 Gene

Subcategory (RNA class) for MIR920 Gene

miRNA

Number of RNA Genes sources:

4 / 14

Aliases for MIR920 Gene

  • MicroRNA 920 2 3 5
  • Hsa-MiR-920 166 177
  • MIMAT0004970 51
  • Hsa-Mir-920 3
  • MI0005712 51
  • MIRN920 3
  • RF00986 172
  • MIR920 2

External Ids for MIR920 Gene

Previous HGNC Symbols for MIR920 Gene

  • MIRN920

Previous GeneCards Identifiers for MIR920 Gene

  • GC12P024258
  • GC12P024365

Summaries for MIR920 Gene

Entrez Gene Summary for MIR920 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR920 Gene

MIR920 (MicroRNA 920) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR920 Gene

Additional gene information for MIR920 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR920 Gene

Genomics for MIR920 Gene

GeneHancer (GH) Regulatory Elements for MIR920 Gene

Promoters and enhancers for MIR920 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J024252 Enhancer 0.8 UCNEbase Ensembl 10.2 +40.8 40780 2.4 ZNF384 GATA2 POLR2A PRDM1 MIR920 lnc-LRMP-10 SOX5-AS1 L13714-079 SOX5 lnc-SOX5-5
GH12J024349 Enhancer 0.4 Ensembl 10.3 +137.1 137080 1.8 FOS GATA2 ZNF34 JUN MIR920 piR-33270-008 L13714-079 SOX5 lnc-SOX5-5
GH12J024245 Enhancer 0.3 ENCODE 11 +32.6 32611 0 FOS STAT3 MIR920 lnc-LRMP-10 SOX5-AS1 SOX5 lnc-SOX5-5
GH12J024244 Enhancer 0.3 Ensembl 11 +32.2 32180 0.8 FOS STAT3 MIR920 lnc-LRMP-10 SOX5-AS1 SOX5 lnc-SOX5-5
GH12J024238 Enhancer 0.3 Ensembl 11 +26.9 26880 2.6 PRDM1 MIR920 lnc-LRMP-10 SOX5-AS1 SOX5 lnc-SOX5-5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR920 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR920 Gene

Genomic Locations for MIR920 Gene
chr12:24,212,421-24,212,495
(GRCh38/hg38)
Size:
75 bases
Orientation:
Plus strand
chr12:24,365,355-24,365,429
(GRCh37/hg19)
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR920 Gene

Genes around MIR920 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR920 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR920 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR920 Gene

Proteins for MIR920 Gene

Post-translational modifications for MIR920 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR920 Gene

Domains & Families for MIR920 Gene

Gene Families for MIR920 Gene

HGNC:
genes like me logo Genes that share domains with MIR920: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR920 Gene

Function for MIR920 Gene

Phenotypes From GWAS Catalog for MIR920 Gene

Gene Ontology (GO) - Molecular Function for MIR920 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 28915828
genes like me logo Genes that share ontologies with MIR920: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR920 Gene

Localization for MIR920 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR920 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR920 Gene

Pathways & Interactions for MIR920 Gene

PathCards logo

SuperPathways for MIR920 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR920 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 28915828
GO:0042536 negative regulation of tumor necrosis factor biosynthetic process IDA 28915828
GO:0045415 negative regulation of interleukin-8 biosynthetic process IDA 28915828
GO:0050724 negative regulation of interleukin-1 beta biosynthetic process IDA 28915828
GO:0050728 negative regulation of inflammatory response IDA 28915828
genes like me logo Genes that share ontologies with MIR920: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR920 Gene

Drugs & Compounds for MIR920 Gene

No Compound Related Data Available

Transcripts for MIR920 Gene

mRNA/cDNA for MIR920 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :
1 LncBase transcripts :
1 Rfam transcripts :
1 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR920 Gene

No ASD Table

Relevant External Links for MIR920 Gene

GeneLoc Exon Structure for
MIR920

Expression for MIR920 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR920

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR920 Gene

Orthologs for MIR920 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR920 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-920 31
  • 96 (a)
OneToOne
Species where no ortholog for MIR920 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR920 Gene

ENSEMBL:
Gene Tree for MIR920 (if available)
TreeFam:
Gene Tree for MIR920 (if available)

Paralogs for MIR920 Gene

No data available for Paralogs for MIR920 Gene

Variants for MIR920 Gene

Additional dbSNP identifiers (rs#s) for MIR920 Gene

Additional Variant Information for MIR920 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR920

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR920 Gene

Disorders for MIR920 Gene

Additional Disease Information for MIR920

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR920 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR920 Gene

Publications for MIR920 Gene

  1. Novel genetic variants in microRNA genes and familial breast cancer. (PMID: 19048628) Shen J … Zhao H (International journal of cancer 2009) 3 41 54
  2. Circulating miR-625 as an Emerging Biomarker for Liver Cirrhosis. (PMID: 30969085) Ghaempoor M … Hatami B (Clinical laboratory 2019) 3 54
  3. MicroRNA-488 and -920 regulate the production of proinflammatory cytokines in acute gouty arthritis. (PMID: 28915828) Zhou W … Shi G (Arthritis research & therapy 2017) 3 54
  4. An insertion/deletion polymorphism in the 3' untranslated region of beta-transducin repeat-containing protein (betaTrCP) is associated with susceptibility for hepatocellular carcinoma in Chinese. (PMID: 19931512) Chen S … Gao Y (Biochemical and biophysical research communications 2010) 3 54
  5. Analysis of gene expression in normal and neoplastic human testis: new roles of RNA. (PMID: 17573847) Novotny GW … Leffers H (International journal of andrology 2007) 3 54

Products for MIR920 Gene

Sources for MIR920 Gene