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Aliases for MIR9-2 Gene

Subcategory (RNA class) for MIR9-2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR9-2 Gene

  • MicroRNA 9-2 2 3 5
  • Hsa-Mir-9-2 3
  • MiRNA9-2 3
  • Mir-9-2 3
  • MIRN9-2 3

External Ids for MIR9-2 Gene

Previous HGNC Symbols for MIR9-2 Gene

  • MIRN9-2

Previous GeneCards Identifiers for MIR9-2 Gene

  • GC05M088001
  • GC05M087962
  • GC05M087805
  • GC05M088508

Summaries for MIR9-2 Gene

Entrez Gene Summary for MIR9-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR9-2 Gene

MIR9-2 (MicroRNA 9-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and MicroRNAs in cancer.

Additional gene information for MIR9-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR9-2 Gene

Genomics for MIR9-2 Gene

GeneHancer (GH) Regulatory Elements for MIR9-2 Gene

Promoters and enhancers for MIR9-2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I088697 Enhancer 1 ENCODE dbSUPER 12 -24.2 -24220 0.2 RB1 BMI1 ZNF2 KLF5 RAD21 ZNF335 ZNF143 ZNF391 BCLAF1 CREM ENSG00000250555 LINC00461 MIR9-2 MEF2C-AS2
GH05I088140 Enhancer 1.1 Ensembl ENCODE 10.3 +525.6 525577 1.7 HDGF PKNOX1 SIN3A ZNF2 YY1 GLIS2 ZNF143 KLF7 ZNF548 ZNF263 TMEM161B LINC00461 MEF2C-AS2 MIR9-2 ENSG00000250377 ENSG00000250555 LOC105379070 GC05P088219
GH05I088700 Enhancer 0.7 FANTOM5 dbSUPER 11.9 -22.8 -22765 0.3 SUZ12 CTBP2 EZH2 LINC00461 MIR9-2 MEF2C MEF2C-AS2
GH05I088142 Enhancer 0.8 Ensembl 10.3 +524.3 524338 0.5 ZSCAN4 ZNF2 ZNF335 EGR1 EGR2 SP3 ZNF362 ZNF398 ZFP69B ZNF512B LINC00461 MEF2C-AS2 MIR9-2 LOC105379070 GC05P088219
GH05I087787 Enhancer 0.7 VISTA 10.3 +878.9 878874 1.7 SP1 ZNF362 POU5F1 ATF2 EZH2 LINC00461 MEF2C-AS2 MIR9-2 GC05P087735 GC05M087850
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR9-2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR9-2 Gene

Genomic Locations for MIR9-2 Gene
chr5:88,666,853-88,666,939
(GRCh38/hg38)
Size:
87 bases
Orientation:
Minus strand
chr5:87,803,363-87,986,858
(GRCh37/hg19)

Genomic View for MIR9-2 Gene

Genes around MIR9-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR9-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR9-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-2 Gene

ORGUL Member Location for MIR9-2 Gene

ORGUL Member Location for MIR9-2 gene

Proteins for MIR9-2 Gene

Post-translational modifications for MIR9-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR9-2 Gene

Domains & Families for MIR9-2 Gene

Gene Families for MIR9-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR9-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR9-2 Gene

Function for MIR9-2 Gene

Phenotypes From GWAS Catalog for MIR9-2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR9-2 Gene

Localization for MIR9-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR9-2 Gene

Pathways & Interactions for MIR9-2 Gene

genes like me logo Genes that share pathways with MIR9-2: view

Pathways by source for MIR9-2 Gene

1 BioSystems pathway for MIR9-2 Gene
1 KEGG pathway for MIR9-2 Gene

Interacting Proteins for MIR9-2 Gene

Gene Ontology (GO) - Biological Process for MIR9-2 Gene

None

No data available for SIGNOR curated interactions for MIR9-2 Gene

Drugs & Compounds for MIR9-2 Gene

No Compound Related Data Available

Transcripts for MIR9-2 Gene

mRNA/cDNA for MIR9-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-2 Gene

No ASD Table

Relevant External Links for MIR9-2 Gene

GeneLoc Exon Structure for
MIR9-2
ECgene alternative splicing isoforms for
MIR9-2

Expression for MIR9-2 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR9-2 Gene

Orthologs for MIR9-2 Gene

Evolution for MIR9-2 Gene

ENSEMBL:
Gene Tree for MIR9-2 (if available)
TreeFam:
Gene Tree for MIR9-2 (if available)

No data available for Orthologs for MIR9-2 Gene

Paralogs for MIR9-2 Gene

No data available for Paralogs for MIR9-2 Gene

Variants for MIR9-2 Gene

Sequence variations from dbSNP and Humsavar for MIR9-2 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
rs1000760868 -- 88,667,477(-) C/A upstream_transcript_variant
rs1000798211 -- 88,667,129(-) C/A upstream_transcript_variant
rs1001554596 -- 88,667,604(-) G/A upstream_transcript_variant
rs1001915846 -- 88,666,471(-) A/C downstream_transcript_variant
rs1005569619 -- 88,668,684(-) T/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR9-2 Gene

Variant ID Type Subtype PubMed ID
nsv524630 CNV loss 19592680

Additional Variant Information for MIR9-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR9-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR9-2 Gene

Disorders for MIR9-2 Gene

Additional Disease Information for MIR9-2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR9-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR9-2 Gene

Publications for MIR9-2 Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J … Zhao H (BMC cancer 2010) 3 44 58
  2. Prognostic value of microRNA-9 and microRNA-155 expression in triple-negative breast cancer. (PMID: 28882698) Jang MH … Park SY (Human pathology 2017) 3 58
  3. MicroRNA-92a Mediates Endothelial Dysfunction in CKD. (PMID: 28696247) Shang F … Shyy JY (Journal of the American Society of Nephrology : JASN 2017) 3 58
  4. miR-9 regulates the multidrug resistance of chronic myelogenous leukemia by targeting ABCB1. (PMID: 28260112) Li Y … Jia L (Oncology reports 2017) 3 58
  5. MicroRNA-9 plays a role in interleukin-10-mediated expression of E-cadherin in acute myelogenous leukemia cells. (PMID: 28107581) Nishioka C … Yokoyama A (Cancer science 2017) 3 58

Products for MIR9-2 Gene

Sources for MIR9-2 Gene

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