Aliases for MIR9-1HG Gene

Subcategory (RNA class) for MIR9-1HG Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR9-1HG Gene

  • MIR9-1 Host Gene 2 3
  • CROC4 2 3 4
  • Chromosome 1 Open Reading Frame 61 2 5
  • Contingent Replication Of CDNA 4 3 4
  • Protein CROC-4 3 4
  • C1orf61 3 5
  • Transcriptional Activator Of The C Fos Promoter 2
  • Transcriptional Activator Of The C-Fos Promoter 3
  • Contingent Replication Of CDNA-4 2
  • NONHSAG003120.2 91
  • Lnc-C1orf61-2 165
  • HSALNG0007582 164

External Ids for MIR9-1HG Gene

Previous HGNC Symbols for MIR9-1HG Gene

  • C1orf61

Summaries for MIR9-1HG Gene

GeneCards Summary for MIR9-1HG Gene

MIR9-1HG (MIR9-1 Host Gene) is an RNA Gene, and is affiliated with the lncRNA class.

UniProtKB/Swiss-Prot Summary for MIR9-1HG Gene

  • May play a role in FOS signaling pathways involved in development and remodeling of neurons. Promotes transcription of the FOS promoter.

Additional gene information for MIR9-1HG Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR9-1HG Gene

Genomics for MIR9-1HG Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR9-1HG Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR9-1HG on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MIR9-1HG

Genomic Locations for MIR9-1HG Gene

Genomic Locations for MIR9-1HG Gene
chr1:156,398,670-156,457,351
(GRCh38/hg38)
Size:
58,682 bases
Orientation:
Minus strand
chr1:156,374,042-156,400,493
(GRCh37/hg19)
Size:
26,452 bases
Orientation:
Minus strand

Genomic View for MIR9-1HG Gene

Genes around MIR9-1HG on UCSC Golden Path with GeneCards custom track
MIR9-1HG in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR9-1HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR9-1HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR9-1HG Gene

Proteins for MIR9-1HG Gene

  • Protein details for MIR9-1HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13536-CROC4_HUMAN
    Recommended name:
    Protein CROC-4
    Protein Accession:
    Q13536
    Secondary Accessions:
    • B1ALL5
    • B1ALL8

    Protein attributes for MIR9-1HG Gene

    Size:
    156 amino acids
    Molecular mass:
    17231 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MIR9-1HG Gene

Post-translational modifications for MIR9-1HG Gene

No Post-translational modifications

Other Protein References for MIR9-1HG Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for MIR9-1HG Gene

Domains & Families for MIR9-1HG Gene

Gene Families for MIR9-1HG Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MIR9-1HG Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MIR9-1HG Gene

GenScript: Design optimal peptide antigens:
  • Chromosome 1 open reading frame 61 (B1ALL3_HUMAN)
  • Contingent replication of cDNA 4 (CROC4_HUMAN)
  • C1orf61 protein (Q6PB34_HUMAN)
  • Chromosome 1 open reading frame 61 (Q86W69_HUMAN)
genes like me logo Genes that share domains with MIR9-1HG: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR9-1HG Gene

Function for MIR9-1HG Gene

Molecular function for MIR9-1HG Gene

UniProtKB/Swiss-Prot Function:
May play a role in FOS signaling pathways involved in development and remodeling of neurons. Promotes transcription of the FOS promoter.

Phenotypes From GWAS Catalog for MIR9-1HG Gene

Gene Ontology (GO) - Molecular Function for MIR9-1HG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MIR9-1HG: view
genes like me logo Genes that share phenotypes with MIR9-1HG: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MIR9-1HG

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR9-1HG Gene

Localization for MIR9-1HG Gene

Subcellular locations from UniProtKB/Swiss-Prot for MIR9-1HG Gene

Nucleus. Note=Associates within the nuclear transcriptional apparatus during proliferation and differentiation.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR9-1HG gene
Compartment Confidence
nucleus 5
extracellular 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for MIR9-1HG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus TAS 10995546
genes like me logo Genes that share ontologies with MIR9-1HG: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MIR9-1HG Gene

Pathways & Interactions for MIR9-1HG Gene

PathCards logo

SuperPathways for MIR9-1HG Gene

No Data Available

Interacting Proteins for MIR9-1HG Gene

Selected Interacting proteins: Q13536-CROC4_HUMAN for MIR9-1HG Gene via IID

Gene Ontology (GO) - Biological Process for MIR9-1HG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045944 positive regulation of transcription by RNA polymerase II IDA 10995546
genes like me logo Genes that share ontologies with MIR9-1HG: view

No data available for Pathways by source and SIGNOR curated interactions for MIR9-1HG Gene

Drugs & Compounds for MIR9-1HG Gene

No Compound Related Data Available

Transcripts for MIR9-1HG Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR9-1HG Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000EED11B_9606 lncRNA 3138 1

Ensembl: ENST00000608007 (view in UCSC) ,

URS0001956A78_9606 lncRNA 1395 1

Ensembl: ENST00000673141 (view in UCSC) ,

URS0000EEB622_9606 lncRNA 920 1

Ensembl: ENST00000368243 (view in UCSC) ,

URS0000EF13CB_9606 lncRNA 867 1

Ensembl: ENST00000368242 (view in UCSC) ,

URS0000EF5CAF_9606 lncRNA 857 1

Ensembl: ENST00000452465 (view in UCSC) ,

MIR9-1HG in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR9-1HG Gene

4 REFSEQ mRNAs :
34 NCBI additional mRNA sequence :
21 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MIR9-1HG

Alternative Splicing Database (ASD) splice patterns (SP) for MIR9-1HG Gene

No ASD Table

Relevant External Links for MIR9-1HG Gene

GeneLoc Exon Structure for
MIR9-1HG

Expression for MIR9-1HG Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR9-1HG

SOURCE GeneReport for Unigene cluster for MIR9-1HG Gene:

Hs.380027

mRNA Expression by UniProt/SwissProt for MIR9-1HG Gene:

Q13536-CROC4_HUMAN
Tissue specificity: Expressed throughout the brain in the thalamus, subthalamic nucleus, corpus callosum, hippocampus, substantia nigra, caudate nucleus, and amygdala.

Evidence on tissue expression from TISSUES for MIR9-1HG Gene

  • Nervous system(5)

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR9-1HG Gene

Orthologs for MIR9-1HG Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR9-1HG Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia C1orf61 31
  • 99 (a)
OneToOne
C1H1orf61 30
  • 89.38 (n)
Species where no ortholog for MIR9-1HG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR9-1HG Gene

ENSEMBL:
Gene Tree for MIR9-1HG (if available)
TreeFam:
Gene Tree for MIR9-1HG (if available)

Paralogs for MIR9-1HG Gene

No data available for Paralogs for MIR9-1HG Gene

Variants for MIR9-1HG Gene

Additional dbSNP identifiers (rs#s) for MIR9-1HG Gene

Variation tolerance for MIR9-1HG Gene

Residual Variation Intolerance Score: 45.6% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MIR9-1HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR9-1HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Structural Variations from Database of Genomic Variants (DGV) for MIR9-1HG Gene

Disorders for MIR9-1HG Gene

No disorders were found for MIR9-1HG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR9-1HG Gene

Publications for MIR9-1HG Gene

  1. CROC-4: a novel brain specific transcriptional activator of c-fos expressed from proliferation through to maturation of multiple neuronal cell types. (PMID: 10995546) Jeffrey PL … Lin SL (Molecular and cellular neurosciences 2000) 2 3 4
  2. C1orf61 acts as a tumor activator in human hepatocellular carcinoma and is associated with tumorigenesis and metastasis. (PMID: 23012322) Hu HM … Li W (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013) 2 3
  3. A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
  4. LncRNA CACNA1G-AS1 facilitates hepatocellular carcinoma progression through the miR-2392/C1orf61 pathway. (PMID: 30908634) Yang J … E C (Journal of cellular physiology 2019) 3
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox CS … Borecki IB (PLoS genetics 2012) 3

No data available for Mastermind for MIR9-1HG Gene

Products for MIR9-1HG Gene

Sources for MIR9-1HG Gene