microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR885 Gene

Subcategory (RNA class) for MIR885 Gene

miRNA

Number of RNA Genes sources:

5 / 14

Aliases for MIR885 Gene

  • MicroRNA 885 2 3 5
  • Hsa-MiR-885-3p 166 177
  • Hsa-MiR-885-5p 166 177
  • MIMAT0004948 51
  • MIMAT0004947 51
  • Hsa-Mir-885 3
  • MI0005560 51
  • Mir-885 3
  • MIRN885 3
  • RF01015 172
  • MIR885 2

External Ids for MIR885 Gene

Previous HGNC Symbols for MIR885 Gene

  • MIRN885

Summaries for MIR885 Gene

Entrez Gene Summary for MIR885 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR885 Gene

MIR885 (MicroRNA 885) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR885 include Mesothelioma, Malignant and Esophageal Disease.

Rfam classification for MIR885 Gene

Additional gene information for MIR885 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR885 Gene

Genomics for MIR885 Gene

GeneHancer (GH) Regulatory Elements for MIR885 Gene

Promoters and enhancers for MIR885 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J010389 Enhancer 1 Ensembl ENCODE dbSUPER 500.7 +1.1 1061 8.6 TEAD4 ZIC2 CTCF ZKSCAN1 NANOG MEF2B TCF12 SPI1 ZFHX2 ELF1 MIR885 SEC13 GHRLOS LINC00852 GHRL MIR378B ATP2B2
GH03J010436 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 11.5 -44.0 -44039 6.4 ZSCAN5C USF1 FOS ZNF639 ZIC2 ZNF623 ATF2 MEF2A ZNF341 NR2F2 MIR885 SEC13 TATDN2 piR-61101-476 ATP2B2
GH03J010370 Enhancer 1 Ensembl ENCODE dbSUPER 12 +24.1 24061 1.8 FOS CTBP1 ZNF316 SPI1 NFE2 FOSL1 MAFK BHLHE40 TCF12 MAFG MIR885 SEC13 GHRL GHRLOS MIR378B ATP2B2
GH03J010460 Enhancer 1 ENCODE 11.4 -65.8 -65750 0.2 FOXK2 ZBTB40 ZNF217 SIN3A MYC USF1 ZIC2 REST KDM6A ZBTB11 MIR885 GHRLOS piR-61101-476 ATP2B2
GH03J010346 Enhancer 1 Ensembl ENCODE dbSUPER 10.9 +50.2 50200 0.6 CTCF REST RAD21 TRIM22 SMC3 ZNF654 SIN3A ZNF2 ZFP36 KLF16 SEC13 MIR885 MIR378B ATP2B2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR885 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR885 Gene

Genomic Locations for MIR885 Gene
chr3:10,394,489-10,394,562
(GRCh38/hg38)
Size:
74 bases
Orientation:
Minus strand
chr3:10,436,173-10,436,246
(GRCh37/hg19)
Size:
74 bases
Orientation:
Minus strand

Genomic View for MIR885 Gene

Genes around MIR885 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR885 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR885 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR885 Gene

Proteins for MIR885 Gene

Post-translational modifications for MIR885 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR885 Gene

Domains & Families for MIR885 Gene

Gene Families for MIR885 Gene

HGNC:
genes like me logo Genes that share domains with MIR885: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR885 Gene

Function for MIR885 Gene

Phenotypes From GWAS Catalog for MIR885 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR885 Gene

Localization for MIR885 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR885 gene
Compartment Confidence
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
cytosol 1
lysosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR885 Gene

Pathways & Interactions for MIR885 Gene

PathCards logo

SuperPathways for MIR885 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR885 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR885 Gene

Drugs & Compounds for MIR885 Gene

No Compound Related Data Available

Transcripts for MIR885 Gene

mRNA/cDNA for MIR885 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :
5 ENA transcripts :
2 LncBase transcripts :
1 Rfam transcripts :
2 TarBase transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR885 Gene

No ASD Table

Relevant External Links for MIR885 Gene

GeneLoc Exon Structure for
MIR885

Expression for MIR885 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR885

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR885 Gene

Orthologs for MIR885 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR885 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-885 31
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-885 31
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-885 31
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 53 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-885 31
  • 51 (a)
OneToOne
Species where no ortholog for MIR885 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR885 Gene

ENSEMBL:
Gene Tree for MIR885 (if available)
TreeFam:
Gene Tree for MIR885 (if available)

Paralogs for MIR885 Gene

No data available for Paralogs for MIR885 Gene

Variants for MIR885 Gene

Additional dbSNP identifiers (rs#s) for MIR885 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR885 Gene

Variant ID Type Subtype PubMed ID
dgv762e201 CNV deletion 23290073
esv4117 OTHER complex 18987735
nsv1073204 CNV deletion 25765185
nsv1121603 CNV deletion 24896259
nsv436362 CNV deletion 17901297
nsv436869 CNV insertion 17901297
nsv508903 CNV insertion 20534489

Additional Variant Information for MIR885 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR885

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR885 Gene

Disorders for MIR885 Gene

MalaCards: The human disease database

(5) MalaCards diseases for MIR885 Gene - From: miR2Disease and DISEASES

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR885

genes like me logo Genes that share disorders with MIR885: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR885 Gene

Publications for MIR885 Gene

  1. Rs739837 Polymorphism in MiR-885-3p Binding Site Within 3'-Untranslated Region of Vitamin D Receptor is Associated with a Decreased Risk of Pressure Ulcers. (PMID: 29241179) Ji X … Zhou S (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017) 2 3 54
  2. Identifying the key genes and microRNAs in colorectal cancer liver metastasis by bioinformatics analysis and in vitro experiments. (PMID: 30542696) Zhang T … Wang J (Oncology reports 2019) 3 54
  3. miR-885-5p plays an accomplice role in liver cancer by instigating TIGAR expression via targeting its promoter. (PMID: 31119791) Zou S … Chen W (Biotechnology and applied biochemistry 2019) 3 54
  4. Long noncoding RNA gastric cancer-related lncRNA1 mediates gastric malignancy through miRNA-885-3p and cyclin-dependent kinase 4. (PMID: 29789536) Lin Z … Wang J (Cell death & disease 2018) 3 54
  5. Upregulated hsa_circ_0004458 Contributes to Progression of Papillary Thyroid Carcinoma by Inhibition of miR-885-5p and Activation of RAC1. (PMID: 30086127) Jin X … Zhang Q (Medical science monitor : international medical journal of experimental and clinical research 2018) 3 54

Products for MIR885 Gene

Sources for MIR885 Gene