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Aliases for MIR8077 Gene

Subcategory (RNA class) for MIR8077 Gene


Quality Score for this RNA gene is


Aliases for MIR8077 Gene

  • MicroRNA 8077 2 3 5
  • MicroRNA Mir-8077 3
  • Hsa-Mir-8077 3

External Ids for MIR8077 Gene

Previous GeneCards Identifiers for MIR8077 Gene

  • GC19U901829

Summaries for MIR8077 Gene

Entrez Gene Summary for MIR8077 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8077 Gene

MIR8077 (MicroRNA 8077) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR8077 include Carpenter Syndrome 2.

Additional gene information for MIR8077 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR8077 Gene

Genomics for MIR8077 Gene

GeneHancer (GH) Regulatory Elements for MIR8077 Gene

Promoters and enhancers for MIR8077 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J042352 Enhancer 0.7 Ensembl ENCODE 600.7 +1.4 1370 1 PRDM1 RFX1 PKNOX1 BMI1 MYNN ZNF366 MIR8077 GC19P042378 MEGF8 PIR47672
GH19J042369 Promoter/Enhancer 1 Ensembl ENCODE 0.4 +19.5 19547 1.8 SP1 ZNF143 SIN3A POLR2A BACH1 POU5F1 EXOSC5 PIR47672 GC19P042378 MIR8077 MEGF8
GH19J042363 Enhancer 0.9 Ensembl ENCODE 0.4 +13.9 13870 4.4 ZNF121 ZNF687 MLLT1 PRDM10 ZNF143 PKNOX1 KLF9 MGA RUNX3 ELF1 MEGF8 CNFN LIPE-AS1 LIPE GSK3A MIR8077 GC19P042378 PIR47672
GH19J042360 Enhancer 0.5 ENCODE 0.4 +9.9 9883 0.2 RFX1 BMI1 ZNF143 CTCF REST CNFN MEGF8 LIPE-AS1 LIPE GSK3A MIR8077 GC19P042378 PIR47672
GH19J042345 Enhancer 0.5 Ensembl 0.4 -5.8 -5830 0.6 CEBPG ZNF140 CEBPB ZNF146 ZNF19 ZNF526 ZNF574 MIR8077 GC19P042331 MEGF8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8077 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR8077 Gene

Genomic Locations for MIR8077 Gene
75 bases
Plus strand

Genomic View for MIR8077 Gene

Genes around MIR8077 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR8077 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8077 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8077 Gene

Proteins for MIR8077 Gene

Post-translational modifications for MIR8077 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8077 Gene

Domains & Families for MIR8077 Gene

Gene Families for MIR8077 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR8077: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR8077 Gene

Function for MIR8077 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8077 Gene

Localization for MIR8077 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8077 Gene

Pathways & Interactions for MIR8077 Gene

PathCards logo

SuperPathways for MIR8077 Gene

No Data Available

Interacting Proteins for MIR8077 Gene

Gene Ontology (GO) - Biological Process for MIR8077 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR8077 Gene

Drugs & Compounds for MIR8077 Gene

No Compound Related Data Available

Transcripts for MIR8077 Gene

mRNA/cDNA for MIR8077 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8077 Gene

No ASD Table

Relevant External Links for MIR8077 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR8077 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR8077 Gene:

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8077 Gene

Orthologs for MIR8077 Gene

Evolution for MIR8077 Gene

Gene Tree for MIR8077 (if available)
Gene Tree for MIR8077 (if available)

No data available for Orthologs for MIR8077 Gene

Paralogs for MIR8077 Gene

No data available for Paralogs for MIR8077 Gene

Variants for MIR8077 Gene

Sequence variations from dbSNP and Humsavar for MIR8077 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs145216125 likely-benign, Carpenter syndrome 2 42,351,693(+) C/T downstream_transcript_variant
rs757551016 likely-benign, Carpenter syndrome 2 42,350,297(+) T/C upstream_transcript_variant
rs141582110 likely-benign, not provided 42,349,480(+) TCACTCAC/TCAC upstream_transcript_variant
rs141383715 uncertain-significance, not provided 42,351,670(+) C/T downstream_transcript_variant
rs1000580675 -- 42,350,825(+) C/A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR8077 Gene

Variant ID Type Subtype PubMed ID
esv2422471 CNV deletion 17116639
esv3574530 CNV gain 25503493
nsv520239 CNV loss 19592680
nsv522854 CNV gain 19592680
nsv526186 CNV gain 19592680

Additional Variant Information for MIR8077 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR8077 Gene

Disorders for MIR8077 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR8077 Gene - From: GeneCards

Disorder Aliases PubMed IDs
carpenter syndrome 2
  • crpt2
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR8077

genes like me logo Genes that share disorders with MIR8077: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR8077 Gene

Publications for MIR8077 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR8077 Gene

Sources for MIR8077 Gene

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