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Aliases for MIR8073 Gene

Subcategory (RNA class) for MIR8073 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR8073 Gene

  • MicroRNA 8073 2 3 5
  • MicroRNA Mir-8073 3
  • Hsa-Mir-8073 3

External Ids for MIR8073 Gene

Previous GeneCards Identifiers for MIR8073 Gene

  • GC13U901040

Summaries for MIR8073 Gene

Entrez Gene Summary for MIR8073 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8073 Gene

MIR8073 (MicroRNA 8073) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR8073 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR8073 Gene

Genomics for MIR8073 Gene

GeneHancer (GH) Regulatory Elements for MIR8073 Gene

Promoters and enhancers for MIR8073 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13J110303 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.3 -32.4 -32438 9.8 ZSCAN5A SUZ12 SIN3A ZNF2 E2F1 ZNF335 ZFHX2 GATA3 GLIS2 ZNF366 COL4A1 COL4A2 MIR8073
GH13J110321 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -8.0 -8012 23.2 INSM2 KLF17 MZF1 FEZF1 ZNF2 ETS1 ZNF366 ZSCAN5C SCRT2 ATF7 COL4A1 COL4A2 MIR8073
GH13J110345 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 +7.2 7160 4.4 CTCF KLF1 MXI1 JUN MAX SIN3A RFX5 GATA3 POLR2A FOSL2 MIR8073 COL4A2 GC13P110400
GH13J110359 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +20.4 20426 4.3 CTCF ZBTB6 EBF1 GATA3 SCRT2 ZSCAN5C ZNF143 PRDM10 FOS ZNF600 MIR8073 GC13P110400 COL4A2
GH13J110370 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +31.9 31873 5.3 PKNOX1 JUN MAX SIN3A EBF1 RELA POLR2A EED RCOR1 IKZF2 COL4A2 COL4A1 ING1 GC13P110400 MIR8073
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8073 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR8073 Gene

Genomic Locations for MIR8073 Gene
chr13:110,340,958-110,341,029
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR8073 Gene

Genes around MIR8073 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR8073 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8073 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8073 Gene

Proteins for MIR8073 Gene

Post-translational modifications for MIR8073 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8073 Gene

Domains & Families for MIR8073 Gene

Gene Families for MIR8073 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR8073: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR8073 Gene

Function for MIR8073 Gene

Phenotypes From GWAS Catalog for MIR8073 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8073 Gene

Localization for MIR8073 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8073 Gene

Pathways & Interactions for MIR8073 Gene

SuperPathways for MIR8073 Gene

No Data Available

Interacting Proteins for MIR8073 Gene

Gene Ontology (GO) - Biological Process for MIR8073 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR8073 Gene

Drugs & Compounds for MIR8073 Gene

No Compound Related Data Available

Transcripts for MIR8073 Gene

mRNA/cDNA for MIR8073 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(2) RNA Central transcripts :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8073 Gene

No ASD Table

Relevant External Links for MIR8073 Gene

GeneLoc Exon Structure for
MIR8073
ECgene alternative splicing isoforms for
MIR8073

Expression for MIR8073 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR8073 Gene:

MIR8073
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8073 Gene

Orthologs for MIR8073 Gene

Evolution for MIR8073 Gene

ENSEMBL:
Gene Tree for MIR8073 (if available)
TreeFam:
Gene Tree for MIR8073 (if available)

No data available for Orthologs for MIR8073 Gene

Paralogs for MIR8073 Gene

No data available for Paralogs for MIR8073 Gene

Variants for MIR8073 Gene

Sequence variations from dbSNP and Humsavar for MIR8073 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000579718 -- 110,339,951(+) C/T upstream_transcript_variant
rs1002081689 -- 110,341,278(+) C/T downstream_transcript_variant
rs1002153394 -- 110,339,555(+) C/A/T upstream_transcript_variant
rs1003120296 -- 110,340,429(+) A/G upstream_transcript_variant
rs1004522033 -- 110,340,398(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR8073 Gene

Variant ID Type Subtype PubMed ID
nsv1038914 CNV loss 25217958
nsv1046423 CNV gain 25217958

Additional Variant Information for MIR8073 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8073

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR8073 Gene

Disorders for MIR8073 Gene

Additional Disease Information for MIR8073

No disorders were found for MIR8073 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8073 Gene

Publications for MIR8073 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR8073 Gene

Sources for MIR8073 Gene

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