microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR8072 Gene

Data sources for MIR8072 Gene:

Subcategory (RNA class) for MIR8072 Gene

miRNA

Aliases for MIR8072 Gene

External Ids for MIR8072 Gene

Previous GeneCards Identifiers for MIR8072 Gene

  • GC12P123851
  • GC12M123296
  • GC12M123297

Summaries for MIR8072 Gene

Entrez Gene Summary for MIR8072 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8072 Gene

MIR8072 (MicroRNA 8072) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR8072 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR8072 Gene

Genomics for MIR8072 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR8072 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J123362 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 250.7 +0.0 33 4 ZSCAN16 CHD2 TBP ZBTB10 SP1 MXD4 BCL11A CEBPA SIX5 NR2C1 MIR8072 SBNO1 DDX55 RSRC2 ZCCHC8 EIF2B1 TMED2-DT CDK2AP1 MTRFR ATP6V0A2
GH12J123363 Promoter/Enhancer 0.6 Ensembl dbSUPER 0.7 +2.3 2342 0.2 ZNF362 SBNO1-AS1 CDK2AP1 MIR8072 SBNO1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8072 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR8072 Gene

Latest Assembly
chr12:123,364,764-123,364,843
(GRCh38/hg38)
Size:
80 bases
Orientation:
Minus strand

Previous Assembly
chr12:123,849,311-123,849,390
(GRCh37/hg19 by Entrez Gene)
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR8072 Gene

Genes around MIR8072 on UCSC Golden Path with GeneCards custom track
MIR8072 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR8072 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8072 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8072 Gene

Proteins for MIR8072 Gene

Post-translational modifications for MIR8072 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8072 Gene

Domains & Families for MIR8072 Gene

Gene Families for MIR8072 Gene

HGNC:
genes like me logo Genes that share domains with MIR8072: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR8072 Gene

Function for MIR8072 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8072 Gene

Localization for MIR8072 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8072 Gene

Pathways & Interactions for MIR8072 Gene

PathCards logo

SuperPathways for MIR8072 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR8072 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR8072 Gene

Drugs & Compounds for MIR8072 Gene

No Compound Related Data Available

Transcripts for MIR8072 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR8072 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E12A_9606 pre_miRNA 80 3

RefSeq: NR_107039,

Ensembl: ENST00000614241 (view in UCSC) ,

miRBase: MI0025908,

URS000075AD9B_9606 miRNA 20 2

RefSeq: NR_107039,

miRBase: MIMAT0030999,

MIR8072 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8072 Gene

No ASD Table

Relevant External Links for MIR8072 Gene

GeneLoc Exon Structure for
MIR8072

No data available for mRNA/cDNA for MIR8072 Gene

Expression for MIR8072 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8072 Gene

Orthologs for MIR8072 Gene

Evolution for MIR8072 Gene

ENSEMBL:
Gene Tree for MIR8072 (if available)
TreeFam:
Gene Tree for MIR8072 (if available)

No data available for Orthologs for MIR8072 Gene

Paralogs for MIR8072 Gene

No data available for Paralogs for MIR8072 Gene

Variants for MIR8072 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR8072 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR8072 Gene

Variant ID Type Subtype PubMed ID
nsv1118251 CNV deletion 24896259

Additional Variant Information for MIR8072 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8072

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR8072 Gene

Disorders for MIR8072 Gene

Additional Disease Information for MIR8072

No disorders were found for MIR8072 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8072 Gene

Publications for MIR8072 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR8072 Gene

Sources for MIR8072 Gene