microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR8070 Gene

Subcategory (RNA class) for MIR8070 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR8070 Gene

  • MicroRNA 8070 2 3 5
  • Hsa-Mir-8070 2 3
  • MIR8070 2 5
  • MicroRNA Mir-8070 3
  • MIMAT0030997 50
  • MI0025906 50

External Ids for MIR8070 Gene

Previous GeneCards Identifiers for MIR8070 Gene

  • GC11U902214

Summaries for MIR8070 Gene

Entrez Gene Summary for MIR8070 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8070 Gene

MIR8070 (MicroRNA 8070) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR8070 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR8070 Gene

Genomics for MIR8070 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR8070 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J011782 Enhancer 0.5 Ensembl 600.7 +0.3 321 0.6 MNT MGA NR3C1 POLR2A SMARCA4 E2F7 L3MBTL2 PKNOX1 MIR8070 USP47 ENSG00000255309 lnc-GALNT18-5 ENSG00000286959 GALNT18
GH11J011787 Enhancer 0.6 ENCODE 0.7 -4.7 -4727 0.2 CTCF FOXA1 REST RAD21 TRIM22 CTBP1 ZNF592 SMC3 GTF2F1 TEAD1 USP47 CSNK2A3 ENSG00000255351 MIR8070 piR-61514-036 ENSG00000286959 GALNT18
GH11J011788 Enhancer 0.6 Ensembl 0.7 -4.4 -4379 0.4 CTCF TRIM22 RAD21 CTBP1 ZNF592 GTF2F1 TEAD1 JUND RFX5 POLR2A USP47 CSNK2A3 ENSG00000255351 MIR8070 piR-61514-036 ENSG00000286959 GALNT18
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8070 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR8070 Gene

Genomic Locations for MIR8070 Gene
chr11:11,783,135-11,783,222
(GRCh38/hg38)
Size:
88 bases
Orientation:
Minus strand

Genomic View for MIR8070 Gene

Genes around MIR8070 on UCSC Golden Path with GeneCards custom track
MIR8070 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR8070 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8070 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8070 Gene

Proteins for MIR8070 Gene

Post-translational modifications for MIR8070 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8070 Gene

Domains & Families for MIR8070 Gene

Gene Families for MIR8070 Gene

HGNC:
genes like me logo Genes that share domains with MIR8070: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR8070 Gene

Function for MIR8070 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8070 Gene

Localization for MIR8070 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8070 Gene

Pathways & Interactions for MIR8070 Gene

PathCards logo

SuperPathways for MIR8070 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR8070 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR8070 Gene

Drugs & Compounds for MIR8070 Gene

No Compound Related Data Available

Transcripts for MIR8070 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR8070 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075AB3F_9606 precursor_RNA 88 4

HGNC: 50274,

RefSeq: NR_107037,

Ensembl: ENST00000616510 (view in UCSC) ,

miRBase: MI0025906,

URS000075E1F5_9606 miRNA 22 2

RefSeq: NR_107037,

miRBase: MIMAT0030997,

MIR8070 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8070 Gene

No ASD Table

Relevant External Links for MIR8070 Gene

GeneLoc Exon Structure for
MIR8070

No data available for mRNA/cDNA for MIR8070 Gene

Expression for MIR8070 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8070 Gene

Orthologs for MIR8070 Gene

Evolution for MIR8070 Gene

ENSEMBL:
Gene Tree for MIR8070 (if available)
TreeFam:
Gene Tree for MIR8070 (if available)

No data available for Orthologs for MIR8070 Gene

Paralogs for MIR8070 Gene

No data available for Paralogs for MIR8070 Gene

Variants for MIR8070 Gene

Additional dbSNP identifiers (rs#s) for MIR8070 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR8070 Gene

Variant ID Type Subtype PubMed ID
nsv483000 CNV loss 15286789
nsv832066 CNV gain 17160897
nsv832067 CNV gain 17160897

Additional Variant Information for MIR8070 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8070

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR8070 Gene

Disorders for MIR8070 Gene

Additional Disease Information for MIR8070

No disorders were found for MIR8070 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8070 Gene

Publications for MIR8070 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR8070 Gene

Sources for MIR8070 Gene