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Aliases for MIR8068 Gene

Subcategory (RNA class) for MIR8068 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR8068 Gene

  • MicroRNA 8068 2 3 5
  • MicroRNA Mir-8068 3
  • Hsa-Mir-8068 3

External Ids for MIR8068 Gene

Previous GeneCards Identifiers for MIR8068 Gene

  • GC11U902129

Summaries for MIR8068 Gene

Entrez Gene Summary for MIR8068 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8068 Gene

MIR8068 (MicroRNA 8068) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR8068 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR8068 Gene

Genomics for MIR8068 Gene

GeneHancer (GH) Regulatory Elements for MIR8068 Gene

Promoters and enhancers for MIR8068 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J028475 Enhancer 0.2 Ensembl 600.7 +1.2 1247 1.8 MIR8068 METTL15 KIF18A GC11M028295
GH11J028462 Enhancer 0.7 Ensembl ENCODE 0.4 +13.5 13468 3.6 MAFK FOXA2 FOS NR2F1 MIR8068 GC11M028295 METTL15
GH11J028482 Enhancer 0.3 Ensembl 0.7 -4.8 -4753 0.2 POLR2A MIR8068 ENSG00000254606 METTL15
GH11J028481 Enhancer 0.3 Ensembl 0.7 -4.1 -4053 0.8 POLR2A MIR8068 ENSG00000254606 METTL15
GH11J028466 Enhancer 0.4 Ensembl ENCODE 0.4 +10.9 10865 1.2 MIR8068 GC11M028295 METTL15
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8068 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR8068 Gene

Genomic Locations for MIR8068 Gene
chr11:28,477,481-28,477,548
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR8068 Gene

Genes around MIR8068 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR8068 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8068 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8068 Gene

Proteins for MIR8068 Gene

Post-translational modifications for MIR8068 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8068 Gene

Domains & Families for MIR8068 Gene

Gene Families for MIR8068 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR8068: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR8068 Gene

Function for MIR8068 Gene

Phenotypes From GWAS Catalog for MIR8068 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8068 Gene

Localization for MIR8068 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8068 Gene

Pathways & Interactions for MIR8068 Gene

PathCards logo

SuperPathways for MIR8068 Gene

No Data Available

Interacting Proteins for MIR8068 Gene

Gene Ontology (GO) - Biological Process for MIR8068 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR8068 Gene

Drugs & Compounds for MIR8068 Gene

No Compound Related Data Available

Transcripts for MIR8068 Gene

mRNA/cDNA for MIR8068 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8068 Gene

No ASD Table

Relevant External Links for MIR8068 Gene

GeneLoc Exon Structure for
MIR8068
ECgene alternative splicing isoforms for
MIR8068

Expression for MIR8068 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR8068 Gene:

MIR8068
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8068 Gene

Orthologs for MIR8068 Gene

Evolution for MIR8068 Gene

ENSEMBL:
Gene Tree for MIR8068 (if available)
TreeFam:
Gene Tree for MIR8068 (if available)

No data available for Orthologs for MIR8068 Gene

Paralogs for MIR8068 Gene

No data available for Paralogs for MIR8068 Gene

Variants for MIR8068 Gene

Sequence variations from dbSNP and Humsavar for MIR8068 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000240471 -- 28,478,109(-) T/C upstream_transcript_variant
rs1001204546 -- 28,477,329(-) A/C downstream_transcript_variant
rs1004375220 -- 28,478,453(-) G/A upstream_transcript_variant
rs1004743161 -- 28,477,293(-) C/G downstream_transcript_variant
rs1005384676 -- 28,479,096(-) T/TAT/TGTAT/TGTGTAT upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR8068 Gene

Variant ID Type Subtype PubMed ID
dgv1084n100 CNV loss 25217958

Additional Variant Information for MIR8068 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8068

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR8068 Gene

Disorders for MIR8068 Gene

Additional Disease Information for MIR8068

No disorders were found for MIR8068 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8068 Gene

Publications for MIR8068 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR8068 Gene

Sources for MIR8068 Gene

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