microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR8061 Gene

Data sources for MIR8061 Gene:

RNA type for MIR8061 Gene

miRNA

Aliases for MIR8061 Gene

External Ids for MIR8061 Gene

Previous GeneCards Identifiers for MIR8061 Gene

  • GC19U901802
  • GC19P054651
  • GC19P054655
  • GC19P055095
  • GC19P055123
  • GC19P055149
  • GC19P055234
  • GC19P054660
  • GC19P054665
  • GC19P054668
  • GC19P054677
  • GC19P054680
  • GC19P054684
  • GC19P055042
  • GC19P055070
  • GC19P055435
  • GC19P055626

Summaries for MIR8061 Gene

Entrez Gene Summary for MIR8061 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8061 Gene

MIR8061 (MicroRNA 8061) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR8061 Gene

Genomics for MIR8061 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR8061 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J054642 Promoter/Enhancer 1.2 EPDnew FANTOM5 Ensembl ENCODE 250.7 -1.8 -1808 4.2 ZNF316 NFE2 PRDM10 MAFK LILRB4 MIR8061 lnc-LILRB4-1 LILRA1 LILRA2 LAIR1 FCAR LILRB1 LILRB3 LILRB2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8061 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR8061 Gene

Latest Assembly
chr19:54,645,309-54,645,383
(GRCh38/hg38)
Size:
75 bases
Orientation:
Plus strand

Previous Assembly
chr19:55,156,760-55,156,834
(GRCh37/hg19 by Entrez Gene)
Size:
75 bases
Orientation:
Plus strand

Alternative Locations (GRCh38/hg38)

  • chr19(ALT_REF_LOCI_1):551,695-551,769 (+)
  • chr19(ALT_REF_LOCI_7):550,188-550,262 (+)
  • chr19(ALT_REF_LOCI_8):371,793-371,867 (+)
  • chr19(ALT_REF_LOCI_9):627,874-627,948 (+)

Genomic View for MIR8061 Gene

Genes around MIR8061 on UCSC Golden Path with GeneCards custom track
MIR8061 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR8061 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8061 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8061 Gene

Proteins for MIR8061 Gene

Post-translational modifications for MIR8061 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8061 Gene

Domains & Families for MIR8061 Gene

Gene Families for MIR8061 Gene

HGNC:
genes like me logo Genes that share domains with MIR8061: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR8061 Gene

Function for MIR8061 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8061 Gene

Localization for MIR8061 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8061 Gene

Pathways & Interactions for MIR8061 Gene

PathCards logo

SuperPathways for MIR8061 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR8061 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR8061 Gene

Drugs & Compounds for MIR8061 Gene

No Compound Related Data Available

Transcripts for MIR8061 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR8061 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075EC42_9606 pre_miRNA 75 3

RefSeq: NR_107028,

Ensembl: ENST00000618936 (view in UCSC) ,

miRBase: MI0025897,

URS000075E23B_9606 miRNA 21 2

RefSeq: NR_107028,

miRBase: MIMAT0030988,

MIR8061 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8061 Gene

No ASD Table

Relevant External Links for MIR8061 Gene

GeneLoc Exon Structure for
MIR8061

No data available for mRNA/cDNA for MIR8061 Gene

Expression for MIR8061 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8061 Gene

Orthologs for MIR8061 Gene

Evolution for MIR8061 Gene

ENSEMBL:
Gene Tree for MIR8061 (if available)
TreeFam:
Gene Tree for MIR8061 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR8061

No data available for Orthologs for MIR8061 Gene

Paralogs for MIR8061 Gene

No data available for Paralogs for MIR8061 Gene

Variants for MIR8061 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR8061 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR8061 Gene

Variant ID Type Subtype PubMed ID
dgv16e196 CNV duplication 17116639
dgv17e196 CNV deletion 17116639
dgv3665n100 CNV gain 25217958
dgv435n27 CNV loss 19166990
dgv6563n54 CNV loss 21841781
esv1216730 CNV deletion 17803354
esv2667609 CNV deletion 23128226
esv2718872 CNV deletion 23290073
esv2718879 CNV deletion 23290073
esv2718885 CNV deletion 23290073
esv2758771 CNV gain+loss 17122850
esv2763132 CNV gain+loss 21179565
esv3644812 CNV loss 21293372
nsv1061041 CNV loss 25217958
nsv1061739 CNV gain+loss 25217958
nsv1160664 CNV deletion 26073780
nsv428372 CNV gain+loss 18775914
nsv458799 CNV gain 19166990
nsv470158 CNV loss 18288195
nsv470159 CNV gain 18288195
nsv516569 CNV gain+loss 19592680
nsv523723 CNV loss 19592680
nsv580240 CNV gain 21841781
nsv580241 CNV loss 21841781
nsv580242 CNV gain 21841781
nsv817871 CNV loss 17921354
nsv828639 CNV loss 20364138
nsv9760 CNV loss 18304495

Additional Variant Information for MIR8061 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8061
Leiden Open Variation Database (LOVD)
MIR8061

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR8061 Gene

Disorders for MIR8061 Gene

Additional Disease Information for MIR8061

No disorders were found for MIR8061 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8061 Gene

Publications for MIR8061 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR8061 Gene

Sources for MIR8061 Gene