microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR8059 Gene

Data sources for MIR8059 Gene:

RNA type for MIR8059 Gene

miRNA

Aliases for MIR8059 Gene

External Ids for MIR8059 Gene

Previous GeneCards Identifiers for MIR8059 Gene

  • GC17U902091

Summaries for MIR8059 Gene

Entrez Gene Summary for MIR8059 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8059 Gene

MIR8059 (MicroRNA 8059) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR8059 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR8059 Gene

Genomics for MIR8059 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR8059 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J050762 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -2.8 -2759 6.6 ZNF600 ZNF580 ATF2 CEBPA ATF3 POLR2A NFIC YY1 HES1 FEZF1 ANKRD40CL HSALNG0117338 lnc-LINC00483-1 WFIKKN2 LUC7L3 ENSG00000253730 ABCC3 MIR8059 lnc-LUC7L3-6
GH17J050779 Enhancer 0.3 ENCODE 0.4 +11.5 11520 0.5 ZNF384 GATA2 ENSG00000285829 WFIKKN2 ANKRD40 CACNA1G CACNA1G-AS1 SPATA20 LOC105371824 EPN3 MIR8059 ANKRD40CL
GH17J050772 Enhancer 0.2 Ensembl 0.7 +3.6 3551 0.4 ANKRD40CL MIR8059 ENSG00000285829 WFIKKN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8059 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR8059 Gene

Latest Assembly
chr17:50,768,650-50,768,730
(GRCh38/hg38)
Size:
81 bases
Orientation:
Plus strand

Previous Assembly
chr17:48,846,011-48,846,091
(GRCh37/hg19 by Entrez Gene)
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR8059 Gene

Genes around MIR8059 on UCSC Golden Path with GeneCards custom track
MIR8059 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR8059 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8059 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8059 Gene

Proteins for MIR8059 Gene

Post-translational modifications for MIR8059 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8059 Gene

Domains & Families for MIR8059 Gene

Gene Families for MIR8059 Gene

HGNC:
genes like me logo Genes that share domains with MIR8059: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR8059 Gene

Function for MIR8059 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8059 Gene

Localization for MIR8059 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8059 Gene

Pathways & Interactions for MIR8059 Gene

PathCards logo

SuperPathways for MIR8059 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR8059 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR8059 Gene

Drugs & Compounds for MIR8059 Gene

No Compound Related Data Available

Transcripts for MIR8059 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR8059 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075E022_9606 precursor_RNA 81 3

RefSeq: NR_107026,

Ensembl: ENST00000620427 (view in UCSC) ,

miRBase: MI0025895,

URS000075EE37_9606 miRNA 22 2

RefSeq: NR_107026,

miRBase: MIMAT0030986,

MIR8059 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8059 Gene

No ASD Table

Relevant External Links for MIR8059 Gene

GeneLoc Exon Structure for
MIR8059

No data available for mRNA/cDNA for MIR8059 Gene

Expression for MIR8059 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8059 Gene

Orthologs for MIR8059 Gene

Evolution for MIR8059 Gene

ENSEMBL:
Gene Tree for MIR8059 (if available)
TreeFam:
Gene Tree for MIR8059 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR8059

No data available for Orthologs for MIR8059 Gene

Paralogs for MIR8059 Gene

No data available for Paralogs for MIR8059 Gene

Variants for MIR8059 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR8059 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR8059 Gene

Variant ID Type Subtype PubMed ID
dgv42n68 CNV loss 17160897

Additional Variant Information for MIR8059 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8059
Leiden Open Variation Database (LOVD)
MIR8059

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR8059 Gene

Disorders for MIR8059 Gene

Additional Disease Information for MIR8059

No disorders were found for MIR8059 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8059 Gene

Publications for MIR8059 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR8059 Gene

Sources for MIR8059 Gene