microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR8052 Gene

Data sources for MIR8052 Gene:

Subcategory (RNA class) for MIR8052 Gene

miRNA

Aliases for MIR8052 Gene

External Ids for MIR8052 Gene

Previous GeneCards Identifiers for MIR8052 Gene

  • GC11U902168

Summaries for MIR8052 Gene

Entrez Gene Summary for MIR8052 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR8052 Gene

MIR8052 (MicroRNA 8052) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR8052 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR8052 Gene

Genomics for MIR8052 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR8052 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J130666 Enhancer 0.5 Ensembl ENCODE 250.7 +0.3 316 1 RAD21 CTCF MIR8052 lnc-ADAMTS15-3 LINC02873 lnc-SNX19-7 ADAMTS15 SNX19
GH11J130674 Enhancer 0.8 Ensembl ENCODE CraniofacialAtlas 0.4 +9.9 9851 4 CEBPB EP300 JUND SP1 BHLHE40 RFX1 PRDM10 MIR8052 lnc-ADAMTS15-3 LINC02873 lnc-SNX19-7 ADAMTS15 SNX19
GH11J130671 Enhancer 0.7 Ensembl ENCODE 0.4 +6.1 6084 2.4 REST RAD21 JUND RFX1 BHLHE40 BMI1 EP300 FOS MIR8052 lnc-ADAMTS15-3 LINC02873 lnc-SNX19-7 ADAMTS15 SNX19
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR8052 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR8052 Gene

Latest Assembly
chr11:130,666,735-130,666,803
(GRCh38/hg38)
Size:
69 bases
Orientation:
Plus strand

Previous Assembly
chr11:130,536,630-130,536,698
(GRCh37/hg19 by Entrez Gene)
Size:
69 bases
Orientation:
Plus strand

Genomic View for MIR8052 Gene

Genes around MIR8052 on UCSC Golden Path with GeneCards custom track
MIR8052 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR8052 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR8052 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR8052 Gene

Proteins for MIR8052 Gene

Post-translational modifications for MIR8052 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR8052 Gene

Domains & Families for MIR8052 Gene

Gene Families for MIR8052 Gene

HGNC:
genes like me logo Genes that share domains with MIR8052: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR8052 Gene

Function for MIR8052 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR8052 Gene

Localization for MIR8052 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR8052 Gene

Pathways & Interactions for MIR8052 Gene

PathCards logo

SuperPathways for MIR8052 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR8052 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR8052 Gene

Drugs & Compounds for MIR8052 Gene

No Compound Related Data Available

Transcripts for MIR8052 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR8052 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DDA0_9606 pre_miRNA 69 3

RefSeq: NR_107019,

Ensembl: ENST00000615217 (view in UCSC) ,

miRBase: MI0025888,

URS000075E2FE_9606 miRNA 22 2

RefSeq: NR_107019,

miRBase: MIMAT0030979,

MIR8052 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR8052 Gene

No ASD Table

Relevant External Links for MIR8052 Gene

GeneLoc Exon Structure for
MIR8052

No data available for mRNA/cDNA for MIR8052 Gene

Expression for MIR8052 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR8052 Gene

Orthologs for MIR8052 Gene

Evolution for MIR8052 Gene

ENSEMBL:
Gene Tree for MIR8052 (if available)
TreeFam:
Gene Tree for MIR8052 (if available)

No data available for Orthologs for MIR8052 Gene

Paralogs for MIR8052 Gene

No data available for Paralogs for MIR8052 Gene

Variants for MIR8052 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR8052 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR8052 Gene

Variant ID Type Subtype PubMed ID
dgv1296n100 CNV gain 25217958
nsv1035733 CNV gain 25217958
nsv1048533 CNV gain 25217958
nsv526747 CNV gain 19592680
nsv556572 CNV gain 21841781

Additional Variant Information for MIR8052 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR8052

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR8052 Gene

Disorders for MIR8052 Gene

Additional Disease Information for MIR8052

No disorders were found for MIR8052 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR8052 Gene

Publications for MIR8052 Gene

  1. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. (PMID: 23612084) Wang HJ … Xie LX (Shock (Augusta, Ga.) 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR8052 Gene

Sources for MIR8052 Gene