microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7975 Gene

Data sources for MIR7975 Gene:

RNA type for MIR7975 Gene

miRNA

Aliases for MIR7975 Gene

External Ids for MIR7975 Gene

Previous GeneCards Identifiers for MIR7975 Gene

  • GC15P074643

Summaries for MIR7975 Gene

Entrez Gene Summary for MIR7975 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7975 Gene

MIR7975 (MicroRNA 7975) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR7975 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7975 Gene

Genomics for MIR7975 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR7975 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J055124 Enhancer 0.2 Ensembl 250.7 -0.8 -809 0.2 MIR7975 piR-41245-122 piR-30188-092 PPP1R12C TNNT1
GH19J055122 Enhancer 0.2 Ensembl 250.7 +0.8 791 0.6 MIR7975 piR-41245-122 EPS8L1 ENSG00000267507 PPP1R12C lnc-PPP1R12C-1 ENSG00000287170 TNNT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7975 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR7975 Gene

Latest Assembly
chr19:55,123,225-55,123,292
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand

Previous Assembly
chr19:55,634,593-55,634,660
(GRCh37/hg19 by Entrez Gene)
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR7975 Gene

Genes around MIR7975 on UCSC Golden Path with GeneCards custom track
MIR7975 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR7975 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7975 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7975 Gene

Proteins for MIR7975 Gene

Post-translational modifications for MIR7975 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7975 Gene

Domains & Families for MIR7975 Gene

Gene Families for MIR7975 Gene

HGNC:
genes like me logo Genes that share domains with MIR7975: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7975 Gene

Function for MIR7975 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7975 Gene

Localization for MIR7975 Gene

Gene Ontology (GO) - Cellular Components for MIR7975 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 31926946
genes like me logo Genes that share ontologies with MIR7975: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR7975 Gene

Pathways & Interactions for MIR7975 Gene

PathCards logo

SuperPathways for MIR7975 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR7975 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR7975 Gene

Drugs & Compounds for MIR7975 Gene

No Compound Related Data Available

Transcripts for MIR7975 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7975 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075D038_9606 precursor_RNA 68 3

RefSeq: NR_107015,

Ensembl: ENST00000619350 (view in UCSC) ,

miRBase: MI0025751,

URS000075D1BE_9606 miRNA 18 2

RefSeq: NR_107015,

miRBase: MIMAT0031178,

MIR7975 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7975 Gene

No ASD Table

Relevant External Links for MIR7975 Gene

GeneLoc Exon Structure for
MIR7975

No data available for mRNA/cDNA for MIR7975 Gene

Expression for MIR7975 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7975 Gene

Orthologs for MIR7975 Gene

Evolution for MIR7975 Gene

ENSEMBL:
Gene Tree for MIR7975 (if available)
TreeFam:
Gene Tree for MIR7975 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR7975

No data available for Orthologs for MIR7975 Gene

Paralogs for MIR7975 Gene

No data available for Paralogs for MIR7975 Gene

Variants for MIR7975 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR7975 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR7975 Gene

Variant ID Type Subtype PubMed ID
dgv1819n106 OTHER inversion 24896259
esv2758772 CNV gain 17122850
esv34356 CNV gain 17911159
esv3644829 CNV gain 21293372
esv3644837 CNV loss 21293372
nsv1055961 CNV gain+loss 25217958
nsv1060034 CNV gain 25217958
nsv1079034 OTHER inversion 25765185
nsv1150276 OTHER inversion 26484159

Additional Variant Information for MIR7975 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7975
Leiden Open Variation Database (LOVD)
MIR7975

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR7975 Gene

Disorders for MIR7975 Gene

Additional Disease Information for MIR7975

No disorders were found for MIR7975 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7975 Gene

Publications for MIR7975 Gene

  1. Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C. (PMID: 31926946) Hu W … Zhang R (Experimental cell research 2020) 3
  2. Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes. (PMID: 23660593) Velthut-Meikas A … Salumets A (Molecular endocrinology (Baltimore, Md.) 2013) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR7975 Gene

Sources for MIR7975 Gene