microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7974 Gene

Subcategory (RNA class) for MIR7974 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR7974 Gene

  • MicroRNA 7974 2 3 5
  • Hsa-Mir-7974 2 3
  • MIR7974 2 5
  • MicroRNA Mir-7974 3
  • MIMAT0031177 50
  • Hsa-MiR-7974 163
  • MI0025750 50

External Ids for MIR7974 Gene

Previous GeneCards Identifiers for MIR7974 Gene

  • GC19U901825
  • GC19M011496

Summaries for MIR7974 Gene

Entrez Gene Summary for MIR7974 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7974 Gene

MIR7974 (MicroRNA 7974) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR7974 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7974 Gene

Genomics for MIR7974 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR7974 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J011496 Promoter/Enhancer 1.3 EPDnew Ensembl ENCODE 600.7 -1.7 -1679 2.2 CTCF ZBTB33 PRDM10 ZNF629 IKZF1 JUND REST RAD21 DPF2 ZNF600 MIR7974 ZNF653 ECSIT ENSG00000267477 lnc-ECSIT-1 ELAVL3
GH19J011489 Enhancer 1.1 FANTOM5 ENCODE 0.7 +5.0 4957 1.9 GATAD2A TFE3 SIX5 ZNF143 RXRB IRF2 SP1 GABPA ZKSCAN8 FOXA2 ZNF491 ZNF441 MIR7974 ELAVL3 lnc-ELAVL3-1 ENSG00000267477 ZNF653
GH19J011478 Promoter/Enhancer 1.6 FANTOM5 Ensembl ENCODE 0.4 +14.4 14421 4 ZNF221 SP1 CREB1 CTCF TEAD4 PRDM10 ZNF629 REST TFE3 RFX1 ELAVL3 lnc-ELAVL3-1 ILF3 KRI1 ZNF136 ZNF627 TIMM29 ZNF44 ZNF441 ZNF625
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7974 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR7974 Gene

Genomic Locations for MIR7974 Gene
chr19:11,495,544-11,495,622
(GRCh38/hg38)
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR7974 Gene

Genes around MIR7974 on UCSC Golden Path with GeneCards custom track
MIR7974 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR7974 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7974 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7974 Gene

Proteins for MIR7974 Gene

Post-translational modifications for MIR7974 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7974 Gene

Domains & Families for MIR7974 Gene

Gene Families for MIR7974 Gene

HGNC:
genes like me logo Genes that share domains with MIR7974: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7974 Gene

Function for MIR7974 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7974 Gene

Localization for MIR7974 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7974 Gene

Pathways & Interactions for MIR7974 Gene

PathCards logo

SuperPathways for MIR7974 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR7974 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR7974 Gene

Drugs & Compounds for MIR7974 Gene

No Compound Related Data Available

Transcripts for MIR7974 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7974 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C799_9606 precursor_RNA 79 4

HGNC: 49992,

RefSeq: NR_107014,

Ensembl: ENST00000615835 (view in UCSC) ,

miRBase: MI0025750,

URS000075E96D_9606 miRNA 24 3

RefSeq: NR_107014,

LncBase: hsa-miR-7974,

miRBase: MIMAT0031177,

MIR7974 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7974 Gene

No ASD Table

Relevant External Links for MIR7974 Gene

GeneLoc Exon Structure for
MIR7974

No data available for mRNA/cDNA for MIR7974 Gene

Expression for MIR7974 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7974 Gene

Orthologs for MIR7974 Gene

Evolution for MIR7974 Gene

ENSEMBL:
Gene Tree for MIR7974 (if available)
TreeFam:
Gene Tree for MIR7974 (if available)

No data available for Orthologs for MIR7974 Gene

Paralogs for MIR7974 Gene

No data available for Paralogs for MIR7974 Gene

Variants for MIR7974 Gene

Additional dbSNP identifiers (rs#s) for MIR7974 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR7974 Gene

Variant ID Type Subtype PubMed ID
nsv519802 CNV loss 19592680

Additional Variant Information for MIR7974 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7974

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR7974 Gene

Disorders for MIR7974 Gene

Additional Disease Information for MIR7974

No disorders were found for MIR7974 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7974 Gene

Publications for MIR7974 Gene

  1. Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes. (PMID: 23660593) Velthut-Meikas A … Salumets A (Molecular endocrinology (Baltimore, Md.) 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR7974 Gene

Sources for MIR7974 Gene