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MIR7974 Gene(RNA Gene)

MicroRNA 7974

GCID:
GC19M011496
GIFtS:
12
Genes Participants
UDN Logo

Aliases for MIR7974 Gene

Subcategory (RNA class) for MIR7974 Gene

miRNA

Quality Score for this RNA gene is

18

Aliases for MIR7974 Gene

  • MicroRNA 7974 2 3 5
  • MicroRNA Mir-7974 3
  • Hsa-Mir-7974 3

External Ids for MIR7974 Gene

ORGUL Members for MIR7974 Gene

Previous GeneCards Identifiers for MIR7974 Gene

  • GC19U901825

Summaries for MIR7974 Gene

Entrez Gene Summary for MIR7974 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7974 Gene

MIR7974 (MicroRNA 7974) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR7974 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7974 Gene

Genomics for MIR7974 Gene

GeneHancer (GH) Regulatory Elements for MIR7974 Gene

Promoters and enhancers for MIR7974 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH19J011496 Enhancer 0.8 ENCODE 600.7 -0.9 -919 0.2 CC2D1A CTCF ZSCAN21 SP7 RAD21 SMARCA4 FOSL2 DPF2 IKZF1 ZBTB33 MIR7974 ECSIT ENSG00000267477 ZNF653
GH19J011497 Enhancer 0.8 ENCODE 600.7 -1.2 -1179 0.2 CC2D1A ZSCAN21 SP7 SMARCA4 FOSL2 DPF2 ZBTB33 ZNF600 CTCF ZNF629 MIR7974 ENSG00000267477 ZNF653
GH19J011498 Promoter 0.6 EPDnew 0.7 -2.7 -2690 0.1 ZNF121 ZNF653 MIR7974 ENSG00000267477
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7974 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7974 Gene

Genomic Locations for MIR7974 Gene
chr19:11,495,544-11,495,622
(GRCh38/hg38)
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR7974 Gene

Genes around MIR7974 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7974 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7974 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR7974 Gene

ORGUL Member Location for MIR7974 Gene

ORGUL Member Location for MIR7974 gene

Proteins for MIR7974 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR7974 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7974 Gene

Domains & Families for MIR7974 Gene

Gene Families for MIR7974 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7974: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR7974 Gene

Function for MIR7974 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7974 Gene

Localization for MIR7974 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7974 Gene

Pathways & Interactions for MIR7974 Gene

GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards
PathCards logo

SuperPathways for MIR7974 Gene

No Data Available

Interacting Proteins for MIR7974 Gene

Gene Ontology (GO) - Biological Process for MIR7974 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR7974 Gene

Drugs & Compounds for MIR7974 Gene

Products:

  1. Drug
GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards
No Compound Related Data Available

Transcripts for MIR7974 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR7974 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7974 Gene

No ASD Table

Relevant External Links for MIR7974 Gene

GeneLoc Exon Structure for
MIR7974
ECgene alternative splicing isoforms for
MIR7974

Expression for MIR7974 Gene

Products:

  1. Primer
  2. Gene Expression Assay
GeneAnalytics - gene set analysis. Cells, Diseases, Pathways, Function and Compounds, relevant to your gene set. Powered by GeneCards

NURSA nuclear receptor signaling pathways regulating expression of MIR7974 Gene:

MIR7974
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7974 Gene

Orthologs for MIR7974 Gene

Evolution for MIR7974 Gene

ENSEMBL:
Gene Tree for MIR7974 (if available)
TreeFam:
Gene Tree for MIR7974 (if available)

No data available for Orthologs for MIR7974 Gene

Paralogs for MIR7974 Gene

No data available for Paralogs for MIR7974 Gene

Variants for MIR7974 Gene

Products:

  1. SNP Genotyping and Copy Number Assay
VarElect - NGS phenotyper. Rapid prioritization of variants from NGS data powered by 100+ GeneCards sources

Sequence variations from dbSNP and Humsavar for MIR7974 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1002197427 -- 11,495,842(-) G/A/C upstream_transcript_variant
rs1002229968 -- 11,495,539(-) A/C downstream_transcript_variant
rs1003196919 -- 11,496,805(-) T/G upstream_transcript_variant
rs1005532809 -- 11,496,537(-) T/A upstream_transcript_variant
rs1006178440 -- 11,495,793(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR7974 Gene

Variant ID Type Subtype PubMed ID
nsv519802 CNV loss 19592680

Additional Variant Information for MIR7974 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7974

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7974 Gene

Disorders for MIR7974 Gene

Additional Disease Information for MIR7974

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR7974 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7974 Gene

Publications for MIR7974 Gene

  1. Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes. (PMID: 23660593) Velthut-Meikas A … Salumets A (Molecular endocrinology (Baltimore, Md.) 2013) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

ExternalLinks

View latest publications for MIR7974 gene in Mastermind

Products for MIR7974 Gene

Sources for MIR7974 Gene

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