Free for academic non-profit institutions. Other users need a Commercial license
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
MIR7852 (MicroRNA 7852) is an RNA Gene, and is affiliated with the miRNA class.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH01J107894 | Promoter/Enhancer | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 250.7 | +0.4 | 353 | 6.5 | FEZF1 EBF1 ZNF843 PRDM6 SPI1 POLR2A MCM2 IKZF1 L3MBTL2 CEBPB | MIR7852 VAV3 PRPF38B VAV3-AS1 SLC25A24 HG984097 TRUND-NNN8-1 NTNG1 | |
GH01J107934 | Enhancer | 1.4 | FANTOM5 ENCODE dbSUPER | 0.3 | +38.9 | 38945 | 3.7 | BCL11A SP1 FEZF1 ZNF217 ELF1 CEBPB SIN3A MBD2 CUX1 ZNF639 | VAV3 VAV3-AS1 HG984097 TRUND-NNN8-1 MIR7852 NTNG1 | |
GH01J107873 | Enhancer | 0.8 | dbSUPER | 0.3 | -21.5 | -21466 | 5 | BCL11A FEZF1 ZEB1 CEBPB ZNF639 EBF1 ZNF843 BCL11B PRDM6 SPI1 | PRPF38B VAV3 VAV3-AS1 lnc-NTNG1-3 MIR7852 NTNG1 | |
GH01J107912 | Enhancer | 0.8 | Ensembl ENCODE dbSUPER | 0.4 | +16.7 | 16678 | 4.6 | CEBPB RFX5 ATF4 SP7 | VAV3 VAV3-AS1 MIR7852 TRUND-NNN8-1 HG984097 NTNG1 | |
GH01J107890 | Enhancer | 0.6 | Ensembl dbSUPER | 0.4 | -6.4 | -6422 | 1.2 | NFE2 MAFK MAFF HSF1 | VAV3 VAV3-AS1 MIR7852 lnc-NTNG1-3 NTNG1 |
RNAcentral Transcript ID | Subcategory | Length (nts) | # of Sources | Source Identifiers and Annotations |
---|---|---|---|---|
URS000075B70F_9606 | pre_miRNA | 82 | 3 |
RefSeq: NR_107006, Ensembl: ENST00000617442 (view in UCSC) , miRBase: MI0025522, |
URS000075B643_9606 | miRNA | 22 | 2 |
RefSeq: NR_107006, miRBase: MIMAT0030427, |
No disorders were found for MIR7852 Gene.