microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7850 Gene

Subcategory (RNA class) for MIR7850 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR7850 Gene

  • MicroRNA 7850 2 3 5
  • Hsa-Mir-7850 2 3
  • MIR7850 2 5
  • MicroRNA Mir-7850 3
  • Hsa-MiR-7850-5p 163
  • MIMAT0030425 50
  • MI0025520 50

External Ids for MIR7850 Gene

Previous GeneCards Identifiers for MIR7850 Gene

  • GC19U901793

Summaries for MIR7850 Gene

Entrez Gene Summary for MIR7850 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7850 Gene

MIR7850 (MicroRNA 7850) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR7850 include Small Cell Osteogenic Sarcoma and Conventional Central Osteosarcoma.

Additional gene information for MIR7850 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7850 Gene

Genomics for MIR7850 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR7850 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J002626 Promoter/Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 600.7 -1.4 -1436 5.9 GATAD2A ZBTB33 REST TFE3 GABPA ZNF143 RXRB NR2C1 TCF12 IKZF2 MIR7850 ZNF77 CACTIN GADD45B SF3A2 GNA11 TLE2 CACTIN-AS1 DOT1L OAZ1
GH19J002615 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -9.9 -9894 10.4 GATAD2A TFE3 POLR2A BACH1 LARP7 GABPA ZNF143 RELA RFX1 ZIC2 piR-32214-326 GADD45B RNU6-993P SLC39A3 PEAK3 DOT1L SPPL2B OAZ1 GNG7 DIRAS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7850 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR7850 Gene

Genomic Locations for MIR7850 Gene
chr19:2,630,715-2,630,793
(GRCh38/hg38)
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR7850 Gene

Genes around MIR7850 on UCSC Golden Path with GeneCards custom track
MIR7850 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR7850 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7850 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7850 Gene

Proteins for MIR7850 Gene

Post-translational modifications for MIR7850 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7850 Gene

Domains & Families for MIR7850 Gene

Gene Families for MIR7850 Gene

HGNC:
genes like me logo Genes that share domains with MIR7850: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7850 Gene

Function for MIR7850 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7850 Gene

Localization for MIR7850 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7850 Gene

Pathways & Interactions for MIR7850 Gene

PathCards logo

SuperPathways for MIR7850 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR7850 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR7850 Gene

Drugs & Compounds for MIR7850 Gene

No Compound Related Data Available

Transcripts for MIR7850 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7850 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075AA54_9606 precursor_RNA 79 4

HGNC: 50118,

RefSeq: NR_107004,

Ensembl: ENST00000618087 (view in UCSC) ,

miRBase: MI0025520,

URS0000759D67_9606 miRNA 21 3

RefSeq: NR_107004,

LncBase: hsa-miR-7850-5p,

miRBase: MIMAT0030425,

MIR7850 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7850 Gene

No ASD Table

Relevant External Links for MIR7850 Gene

GeneLoc Exon Structure for
MIR7850

No data available for mRNA/cDNA for MIR7850 Gene

Expression for MIR7850 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7850 Gene

Orthologs for MIR7850 Gene

Evolution for MIR7850 Gene

ENSEMBL:
Gene Tree for MIR7850 (if available)
TreeFam:
Gene Tree for MIR7850 (if available)

No data available for Orthologs for MIR7850 Gene

Paralogs for MIR7850 Gene

No data available for Paralogs for MIR7850 Gene

Variants for MIR7850 Gene

Additional dbSNP identifiers (rs#s) for MIR7850 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR7850 Gene

Variant ID Type Subtype PubMed ID
esv3574275 CNV gain 25503493
nsv1056064 CNV loss 25217958
nsv470109 CNV loss 18288195
nsv509714 CNV insertion 20534489
nsv833708 CNV loss 17160897

Additional Variant Information for MIR7850 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7850

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR7850 Gene

Disorders for MIR7850 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR7850 Gene - From: DISEASES

Disorder Aliases PubMed IDs
small cell osteogenic sarcoma
  • round cell osteosarcoma
conventional central osteosarcoma
  • conventional osteosarcoma
bone osteosarcoma
  • osteosarcoma of bone
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR7850

genes like me logo Genes that share disorders with MIR7850: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7850 Gene

Publications for MIR7850 Gene

  1. The repertoire and features of human platelet microRNAs. (PMID: 23226537) Plé H … Provost P (PloS one 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR7850 Gene

Sources for MIR7850 Gene