microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7846 Gene

Subcategory (RNA class) for MIR7846 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR7846 Gene

  • MicroRNA 7846 2 3 5
  • MicroRNA Mir-7846 3
  • Hsa-Mir-7846 3
  • MIMAT0030421 53
  • MI0025516 53
  • MIR7846 2

External Ids for MIR7846 Gene

Previous GeneCards Identifiers for MIR7846 Gene

  • GC01U904214

Summaries for MIR7846 Gene

Entrez Gene Summary for MIR7846 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7846 Gene

MIR7846 (MicroRNA 7846) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System.

Additional gene information for MIR7846 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7846 Gene

Genomics for MIR7846 Gene

GeneHancer (GH) Regulatory Elements for MIR7846 Gene

Promoters and enhancers for MIR7846 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J012165 Enhancer 0.8 FANTOM5 ENCODE dbSUPER 750.6 -1.4 -1443 0.3 IKZF1 STAT1 TNFRSF1B MIR7846 MTHFR CLCN6 TNFRSF8 AGTRAP MFN2 lnc-KIAA2013-6
GH01J012166 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 +10.1 10068 21.6 ZNF24 ZBTB40 FOXA1 SMARCE1 POLR2A RUNX1 MYC CC2D1A ELF1 L3MBTL2 TNFRSF1B MTHFR AGTRAP TNFRSF8 CLCN6 VPS13D SNORA59A KIAA2013 MIIP MFN2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7846 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7846 Gene

Genomic Locations for MIR7846 Gene
chr1:12,166,943-12,167,038
(GRCh38/hg38)
Size:
96 bases
Orientation:
Plus strand

Genomic View for MIR7846 Gene

Genes around MIR7846 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7846 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7846 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7846 Gene

Proteins for MIR7846 Gene

Post-translational modifications for MIR7846 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7846 Gene

Domains & Families for MIR7846 Gene

Gene Families for MIR7846 Gene

HGNC:
genes like me logo Genes that share domains with MIR7846: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7846 Gene

Function for MIR7846 Gene

Phenotypes From GWAS Catalog for MIR7846 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7846 Gene

Localization for MIR7846 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7846 Gene

Pathways & Interactions for MIR7846 Gene

genes like me logo Genes that share pathways with MIR7846: view

Gene Ontology (GO) - Biological Process for MIR7846 Gene

None

No data available for SIGNOR curated interactions for MIR7846 Gene

Drugs & Compounds for MIR7846 Gene

No Compound Related Data Available

Transcripts for MIR7846 Gene

mRNA/cDNA for MIR7846 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNACentral transcripts :
(2) miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7846 Gene

No ASD Table

Relevant External Links for MIR7846 Gene

GeneLoc Exon Structure for
MIR7846
ECgene alternative splicing isoforms for
MIR7846

Expression for MIR7846 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR7846 Gene:

MIR7846
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7846 Gene

Orthologs for MIR7846 Gene

Evolution for MIR7846 Gene

ENSEMBL:
Gene Tree for MIR7846 (if available)
TreeFam:
Gene Tree for MIR7846 (if available)

No data available for Orthologs for MIR7846 Gene

Paralogs for MIR7846 Gene

No data available for Paralogs for MIR7846 Gene

Variants for MIR7846 Gene

Sequence variations from dbSNP and Humsavar for MIR7846 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1001542028 -- 12,167,182(+) C/T downstream_transcript_variant
rs1001926652 -- 12,166,376(+) C/T upstream_transcript_variant
rs1002117103 -- 12,167,394(+) C/T downstream_transcript_variant
rs1004021960 -- 12,167,204(+) C/A downstream_transcript_variant
rs1005278835 -- 12,165,664(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR7846 Gene

Variant ID Type Subtype PubMed ID
esv3584475 CNV gain 24956385
nsv469830 CNV loss 16826518
nsv471622 CNV gain+loss 15918152
nsv508891 CNV insertion 20534489
nsv527024 CNV loss 19592680

Additional Variant Information for MIR7846 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7846

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7846 Gene

Disorders for MIR7846 Gene

Additional Disease Information for MIR7846

No disorders were found for MIR7846 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7846 Gene

Publications for MIR7846 Gene

  1. The repertoire and features of human platelet microRNAs. (PMID: 23226537) Plé H … Provost P (PloS one 2012) 3 56
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 56

Products for MIR7846 Gene

Sources for MIR7846 Gene