microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7705 Gene

Subcategory (RNA class) for MIR7705 Gene

miRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR7705 Gene

  • MicroRNA 7705 2 3 5
  • Hsa-Mir-7705 2 3
  • MIR7705 2 5
  • MicroRNA Mir-7705 3
  • Hsa-MiR-7705 163
  • MIMAT0030020 50
  • MI0025241 50

External Ids for MIR7705 Gene

Previous GeneCards Identifiers for MIR7705 Gene

  • GC08U901845

Summaries for MIR7705 Gene

Entrez Gene Summary for MIR7705 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7705 Gene

MIR7705 (MicroRNA 7705) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR7705 include Retinitis Pigmentosa 41 and Usher Syndrome, Type Ig. Among its related pathways are Viral mRNA Translation and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S.

Additional gene information for MIR7705 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7705 Gene

Genomics for MIR7705 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR7705 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J100683 Enhancer 0.5 Ensembl 0.4 +18.6 18623 1.2 ZNF512 PRDM1 ZNF512B ZKSCAN1 USF1 NONO NCOA3 ZNF366 SUZ12 RF00026-1094 RNU6-1092P PABPC1 MIR7705 SNX31
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7705 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR7705 Gene

Genomic Locations for MIR7705 Gene
chr8:100,702,968-100,703,024
(GRCh38/hg38)
Size:
57 bases
Orientation:
Minus strand

Genomic View for MIR7705 Gene

Genes around MIR7705 on UCSC Golden Path with GeneCards custom track
MIR7705 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR7705 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7705 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7705 Gene

Proteins for MIR7705 Gene

Post-translational modifications for MIR7705 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7705 Gene

Domains & Families for MIR7705 Gene

Gene Families for MIR7705 Gene

HGNC:
genes like me logo Genes that share domains with MIR7705: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7705 Gene

Function for MIR7705 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7705 Gene

Localization for MIR7705 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7705 Gene

Pathways & Interactions for MIR7705 Gene

genes like me logo Genes that share pathways with MIR7705: view

Gene Ontology (GO) - Biological Process for MIR7705 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR7705 Gene

Drugs & Compounds for MIR7705 Gene

No Compound Related Data Available

Transcripts for MIR7705 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7705 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BD23_9606 precursor_RNA 57 4

HGNC: 50143,

RefSeq: NR_106992,

Ensembl: ENST00000614758 (view in UCSC) ,

miRBase: MI0025241,

URS000060B2B9_9606 miRNA 23 4

RefSeq: NR_106992,

LncBase: hsa-miR-7705,

miRBase: MIMAT0030020,

ENA: KC832802.1:1..23:ncRNA,

MIR7705 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR7705 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7705 Gene

No ASD Table

Relevant External Links for MIR7705 Gene

GeneLoc Exon Structure for
MIR7705

Expression for MIR7705 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7705 Gene

Orthologs for MIR7705 Gene

Evolution for MIR7705 Gene

ENSEMBL:
Gene Tree for MIR7705 (if available)
TreeFam:
Gene Tree for MIR7705 (if available)

No data available for Orthologs for MIR7705 Gene

Paralogs for MIR7705 Gene

No data available for Paralogs for MIR7705 Gene

Variants for MIR7705 Gene

Additional dbSNP identifiers (rs#s) for MIR7705 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR7705 Gene

Variant ID Type Subtype PubMed ID
nsv971340 CNV duplication 23825009

Additional Variant Information for MIR7705 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7705

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR7705 Gene

Disorders for MIR7705 Gene

MalaCards: The human disease database

(4) MalaCards diseases for MIR7705 Gene - From: DISEASES

Disorder Aliases PubMed IDs
retinitis pigmentosa 41
  • rp41
usher syndrome, type ig
  • ush1g
retinitis pigmentosa 27
  • rp27
bladder urothelial carcinoma
  • bladder transitional cell carcinoma
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR7705

genes like me logo Genes that share disorders with MIR7705: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7705 Gene

Publications for MIR7705 Gene

  1. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
  2. Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties. (PMID: 23535375) Swaminathan S … Imamichi T (Biochemical and biophysical research communications 2013) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR7705 Gene

Sources for MIR7705 Gene