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Aliases for MIR769 Gene

Subcategory (RNA class) for MIR769 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR769 Gene

  • MicroRNA 769 2 3 5
  • Hsa-Mir-769 3
  • Mir-769 3
  • MIRN769 3

External Ids for MIR769 Gene

ORGUL Members for MIR769 Gene

Previous HGNC Symbols for MIR769 Gene

  • MIRN769

Previous GeneCards Identifiers for MIR769 Gene

  • GC19P051215
  • GC19P046522

Summaries for MIR769 Gene

Entrez Gene Summary for MIR769 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR769 Gene

MIR769 (MicroRNA 769) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

Additional gene information for MIR769 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR769 Gene

Genomics for MIR769 Gene

GeneHancer (GH) Regulatory Elements for MIR769 Gene

Promoters and enhancers for MIR769 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I045952 Enhancer 1.1 Ensembl ENCODE 11.3 -64.2 -64243 4.7 ATF1 ZNF133 ARID4B SIN3A GLI4 ZNF2 ZNF766 GLIS2 ZNF213 E2F8 GC19M045925 CCDC61 MYPOP MIR769 PGLYRP1 FOXA3 SYMPK IGFL4 HIF3A DMWD
GH19I046263 Enhancer 0.9 ENCODE 11.1 +244.2 244167 0.2 FEZF1 IRF4 ELK1 ATF7 FOS RUNX3 SP3 YY2 JUNB TSHZ1 IRF2BP1 ZC3H4 CCDC61 PPP5D1 ENSG00000269124 NOVA2 ENSG00000268810 PNMA8A HIF3A IGFL4
GH19I046265 Enhancer 0.7 ENCODE 11.1 +246.5 246507 0.2 CTCF MAX BATF IRF4 RAD21 ZNF335 CC2D1A SCRT2 SMC3 ZNF143 HIF3A IGFL4 PGLYRP1 MIR769 CCDC61 NOVA2 IGFL1P2
GH19I046065 Enhancer 0.6 ENCODE 11.5 +46.8 46786 0.2 SMARCE1 STAT1 BDP1 JUN CEBPB DPF2 GATA3 JUND POLR3A STAT3 PIR33092 IRF2BP1 PPP1R37 ENSG00000268810 PGLYRP1 MIR769 PPP5C HIF3A PIR35316 IGFL4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR769 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR769 Gene

Genomic Locations for MIR769 Gene
chr19:46,018,932-46,019,049
(GRCh38/hg38)
Size:
118 bases
Orientation:
Plus strand
chr19:46,522,190-46,522,307
(GRCh37/hg19)

Genomic View for MIR769 Gene

Genes around MIR769 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR769 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR769 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR769 Gene

Proteins for MIR769 Gene

Post-translational modifications for MIR769 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR769 Gene

Domains & Families for MIR769 Gene

Gene Families for MIR769 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR769: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR769 Gene

Function for MIR769 Gene

Animal Model Products

miRNA for MIR769 Gene

miRTarBase miRNAs that target MIR769

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR769 Gene

Localization for MIR769 Gene

Gene Ontology (GO) - Cellular Components for MIR769 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR769: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR769 Gene

Pathways & Interactions for MIR769 Gene

genes like me logo Genes that share pathways with MIR769: view

Pathways by source for MIR769 Gene

1 BioSystems pathway for MIR769 Gene

Interacting Proteins for MIR769 Gene

Gene Ontology (GO) - Biological Process for MIR769 Gene

None

No data available for SIGNOR curated interactions for MIR769 Gene

Drugs & Compounds for MIR769 Gene

No Compound Related Data Available

Transcripts for MIR769 Gene

mRNA/cDNA for MIR769 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR769 Gene

No ASD Table

Relevant External Links for MIR769 Gene

GeneLoc Exon Structure for
MIR769
ECgene alternative splicing isoforms for
MIR769

Expression for MIR769 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR769 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR769 Gene:

MIR769
genes like me logo Genes that share expression patterns with MIR769: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR769 Gene

Orthologs for MIR769 Gene

Evolution for MIR769 Gene

ENSEMBL:
Gene Tree for MIR769 (if available)
TreeFam:
Gene Tree for MIR769 (if available)

No data available for Orthologs for MIR769 Gene

Paralogs for MIR769 Gene

No data available for Paralogs for MIR769 Gene

Variants for MIR769 Gene

Sequence variations from dbSNP and Humsavar for MIR769 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000675954 -- 46,018,004(+) T/C upstream_transcript_variant
rs1002143759 -- 46,018,546(+) C/T upstream_transcript_variant
rs1002811171 -- 46,019,494(+) CCCCC/CCCCCC downstream_transcript_variant
rs1004527604 -- 46,018,296(+) G/C upstream_transcript_variant
rs1006432416 -- 46,018,081(+) T/A upstream_transcript_variant

Additional Variant Information for MIR769 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR769

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR769 Gene

Disorders for MIR769 Gene

Additional Disease Information for MIR769

No disorders were found for MIR769 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR769 Gene

Publications for MIR769 Gene

  1. Characterization of a novel panel of plasma microRNAs that discriminates between Mycobacterium tuberculosis infection and healthy individuals. (PMID: 28910318) Cui JY … Ling H (PloS one 2017) 3 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. MiR-769 promoted cell proliferation in human melanoma by suppressing GSK3B expression. (PMID: 27470346) Qiu HJ … Chen FC (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 58
  4. MicroRNA-769-3p down-regulates NDRG1 and enhances apoptosis in MCF-7 cells during reoxygenation. (PMID: 25081069) Luo EC … Lai LC (Scientific reports 2014) 3 58
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58

Products for MIR769 Gene

Sources for MIR769 Gene

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