microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR762 Gene

Subcategory (RNA class) for MIR762 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR762 Gene

  • MicroRNA 762 2 3 5
  • Hsa-Mir-762 2 3
  • MIR762 2 5
  • MIMAT0010313 50
  • MI0003892 50

External Ids for MIR762 Gene

Previous GeneCards Identifiers for MIR762 Gene

  • GC00U923293
  • GC16M030846
  • GC16P030909

Summaries for MIR762 Gene

Entrez Gene Summary for MIR762 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR762 Gene

MIR762 (MicroRNA 762) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR762 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR762 Gene

Genomics for MIR762 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR762 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J030892 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +1.3 1282 5.1 BRCA1 ARHGAP35 CEBPG GATAD2A PRDM10 TFE3 SIX5 IKZF1 KDM1A CTCF BCL7C CTF1 ENSG00000262721 MIR762 ENSG00000260267 SRCAP INO80E SETD1A FUS SMG1P5
GH16J030893 Promoter/Enhancer 0.6 Ensembl dbSUPER 600.7 -1.4 -1402 0.2 ZNF600 MIR762 ZNF629 BCL7C ENSG00000262721 MIR4519 MIR762HG
GH16J030760 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 10.8 -131.8 -131802 4.2 CEBPG SP1 CREB1 GATAD2A PRDM10 ZNF629 TFE3 RFX1 IKZF1 ZNF692 CCDC189 RNF40 lnc-ZNF629-2 piR-51631 SRCAP ZNF747 FUS SETD1A BCL7C KAT8
GH16J030813 Promoter/Enhancer 1.6 FANTOM5 ENCODE CraniofacialAtlas 11.8 -79.7 -79711 2.1 CEBPG SP1 HNRNPL CREB1 GATAD2A CTCF ATF7 PRDM10 ZNF629 TFE3 ENSG00000274848 lnc-RNF40-5 SRCAP INO80E RNF40 ZNF764 SETD1A FUS HSD3B7 FBRS
GH16J030805 Promoter/Enhancer 1.6 ENCODE CraniofacialAtlas 11.4 -87.6 -87586 2.6 ZNF221 SP1 HNRNPL CREB1 GATAD2A ZBTB33 PRDM10 ZNF629 TFE3 SIX5 lnc-RNF40-4 SRCAP SETD1A INO80E RNF40 FUS ZNF764 ZNF720 RUSF1 FBRS
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR762 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR762 Gene

Genomic Locations for MIR762 Gene
chr16:30,893,903-30,893,985
(GRCh38/hg38)
Size:
83 bases
Orientation:
Plus strand
chr16:30,905,224-30,905,306
(GRCh37/hg19)
Size:
83 bases
Orientation:
Plus strand

Genomic View for MIR762 Gene

Genes around MIR762 on UCSC Golden Path with GeneCards custom track
MIR762 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR762 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR762 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR762 Gene

Proteins for MIR762 Gene

Post-translational modifications for MIR762 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR762 Gene

Domains & Families for MIR762 Gene

Gene Families for MIR762 Gene

HGNC:
genes like me logo Genes that share domains with MIR762: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR762 Gene

Function for MIR762 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR762 Gene

Localization for MIR762 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR762 Gene

Pathways & Interactions for MIR762 Gene

PathCards logo

SuperPathways for MIR762 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR762 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR762 Gene

Drugs & Compounds for MIR762 Gene

No Compound Related Data Available

Transcripts for MIR762 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR762 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075DA19_9606 precursor_RNA 83 4

HGNC: 37303,

RefSeq: NR_031576,

Ensembl: ENST00000390236 (view in UCSC) ,

miRBase: MI0003892,

URS0000327AFF_9606 miRNA 22 2

RefSeq: NR_031576,

miRBase: MIMAT0010313,

MIR762 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR762 Gene

No ASD Table

Relevant External Links for MIR762 Gene

GeneLoc Exon Structure for
MIR762

No data available for mRNA/cDNA for MIR762 Gene

Expression for MIR762 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR762 Gene

genes like me logo Genes that share expression patterns with MIR762: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR762 Gene

Orthologs for MIR762 Gene

Evolution for MIR762 Gene

ENSEMBL:
Gene Tree for MIR762 (if available)
TreeFam:
Gene Tree for MIR762 (if available)

No data available for Orthologs for MIR762 Gene

Paralogs for MIR762 Gene

No data available for Paralogs for MIR762 Gene

Variants for MIR762 Gene

Additional dbSNP identifiers (rs#s) for MIR762 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR762 Gene

Variant ID Type Subtype PubMed ID
dgv35n68 CNV loss 17160897
nsv457483 CNV loss 19166990
nsv571820 CNV loss 21841781
nsv833189 CNV loss 17160897
nsv953802 CNV deletion 24416366

Additional Variant Information for MIR762 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR762

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR762 Gene

Disorders for MIR762 Gene

Additional Disease Information for MIR762

No disorders were found for MIR762 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR762 Gene

Publications for MIR762 Gene

  1. CircTRNC18 inhibits trophoblast cell migration and epithelial-mesenchymal transition by regulating miR-762/Grhl2 pathway in pre-eclampsia. (PMID: 31354028) Shen XY … Xin H (RNA biology 2019) 3
  2. Circulating microRNA-144-3p and miR-762 are novel biomarkers of Graves' disease. (PMID: 30949910) Yao Q … Qin Q (Endocrine 2019) 3
  3. miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer. (PMID: 31823748) Ge P … Yue W (BMC cancer 2019) 3
  4. microRNA-762 promotes breast cancer cell proliferation and invasion by targeting IRF7 expression. (PMID: 26597380) Li Y … Yun J (Cell proliferation 2015) 3
  5. MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host defense genes encoding RNase7 and ST2. (PMID: 23469087) Mun J … Fleiszig S (PloS one 2013) 3

Products for MIR762 Gene

Sources for MIR762 Gene