Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR760 Gene

Subcategory (RNA class) for MIR760 Gene


Quality Score for this RNA gene is


Aliases for MIR760 Gene

  • MicroRNA 760 2 3 5
  • Hsa-Mir-760 3
  • Mir-760 3
  • MIRN760 3

External Ids for MIR760 Gene

Previous HGNC Symbols for MIR760 Gene

  • MIRN760

Previous GeneCards Identifiers for MIR760 Gene

  • GC01P094086
  • GC01P094312

Summaries for MIR760 Gene

Entrez Gene Summary for MIR760 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR760 Gene

MIR760 (MicroRNA 760) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

Additional gene information for MIR760 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR760 Gene

Genomics for MIR760 Gene

GeneHancer (GH) Regulatory Elements for MIR760 Gene

Promoters and enhancers for MIR760 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I093844 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 -0.3 -257 4.5 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 SP3 NFYC TRR-TCT1-1 GC01P093849 GC01P093859 MIR760 PIR62105 BCAR3 CCDC18-AS1 MTF2 MIG7 DR1
GH01I093877 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.7 +32.0 31962 2.7 SMAD1 ARNT ARID4B SIN3A DMAP1 YBX1 ZNF2 IRF4 YY1 SLC30A9 DNTTIP2 MIG7 GCLM MIR760 BCAR3 CCDC18-AS1 DR1 TRR-TCT1-1 CCDC18 GC01P093858
GH01I093612 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE dbSUPER 11.2 -230.5 -230526 8.3 FOXA2 MLX ZFP64 ARID4B FEZF1 DMAP1 IRF4 YY1 FOS SP5 BCAR3 LOC100129046 MIR760 GCLM CCDC18-AS1 GC01M093588 GC01M093613
GH01I093811 Enhancer 1.4 Ensembl ENCODE dbSUPER 12.8 -31.7 -31718 8 PKNOX1 ARID4B SIN3A FEZF1 ZNF2 IRF4 ZNF48 TCF12 ARID2 ZNF207 GC01P093813 MIG7 MIR760 BCAR3 GCLM TRR-TCT1-1 PIR45430 GC01M093831
GH01I093757 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11 -87.8 -87754 2.4 FOXA2 MLX DMAP1 ZNF48 ETS1 YY1 ATF7 FOS RXRA ZHX2 MIG7 BCAR3 MIR760 GCLM DNTTIP2 GC01P093728
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR760 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR760 Gene

Genomic Locations for MIR760 Gene
80 bases
Plus strand

Genomic View for MIR760 Gene

Genes around MIR760 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR760 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR760 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR760 Gene

Proteins for MIR760 Gene

Post-translational modifications for MIR760 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR760 Gene

Domains & Families for MIR760 Gene

Gene Families for MIR760 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR760: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR760 Gene

Function for MIR760 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR760 Gene

Localization for MIR760 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR760 Gene

Pathways & Interactions for MIR760 Gene

genes like me logo Genes that share pathways with MIR760: view

Pathways by source for MIR760 Gene

1 BioSystems pathway for MIR760 Gene

Interacting Proteins for MIR760 Gene

Gene Ontology (GO) - Biological Process for MIR760 Gene


No data available for SIGNOR curated interactions for MIR760 Gene

Drugs & Compounds for MIR760 Gene

No Compound Related Data Available

Transcripts for MIR760 Gene

mRNA/cDNA for MIR760 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR760 Gene

No ASD Table

Relevant External Links for MIR760 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR760 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR760 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR760 Gene:

genes like me logo Genes that share expression patterns with MIR760: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR760 Gene

Orthologs for MIR760 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR760 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-760 34
  • 100 (a)
(Bos Taurus)
Mammalia bta-mir-760 34
  • 68 (a)
(Mus musculus)
Mammalia Mir760 34
  • 66 (a)
(Canis familiaris)
Mammalia -- 34
  • 60 (a)
Species where no ortholog for MIR760 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR760 Gene

Gene Tree for MIR760 (if available)
Gene Tree for MIR760 (if available)

Paralogs for MIR760 Gene

No data available for Paralogs for MIR760 Gene

Variants for MIR760 Gene

Sequence variations from dbSNP and Humsavar for MIR760 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1002420801 -- 93,847,332(+) A/C downstream_transcript_variant
rs1004432599 -- 93,846,365(+) C/T upstream_transcript_variant
rs1005485257 -- 93,845,471(+) T/G upstream_transcript_variant
rs1005564294 -- 93,846,710(+) C/G upstream_transcript_variant
rs1009054971 -- 93,844,936(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR760 Gene

Variant ID Type Subtype PubMed ID
nsv998755 CNV loss 25217958

Additional Variant Information for MIR760 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR760 Gene

Disorders for MIR760 Gene

Additional Disease Information for MIR760

No disorders were found for MIR760 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR760 Gene

Publications for MIR760 Gene

  1. The expression profiling of serum miR-92a, miR-375, and miR-760 in colorectal cancer: An Egyptian study. (PMID: 28618945) Elshafei A … Salman T (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
  2. MiR-760 overexpression promotes proliferation in ovarian cancer by downregulation of PHLPP2 expression. (PMID: 27726922) Liao Y … He S (Gynecologic oncology 2016) 3 58
  3. MicroR-760 suppresses cancer stem cell subpopulation and breast cancer cell proliferation and metastasis: By down-regulating NANOG. (PMID: 27133070) Han ML … Wang YM (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 3 58
  4. Systematic analysis of gene expression pattern in has-miR-760 overexpressed resistance of the MCF-7 human breast cancer cell to doxorubicin. (PMID: 25661353) Lv J … Xie H (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015) 3 58
  5. Upregulation of miR-760 and miR-186 is associated with replicative senescence in human lung fibroblast cells. (PMID: 25139266) Lee YH … Bae YS (Molecules and cells 2014) 3 58

Products for MIR760 Gene

Sources for MIR760 Gene

Loading form....