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Aliases for MIR759 Gene

Subcategory (RNA class) for MIR759 Gene


Quality Score for this RNA gene is


Aliases for MIR759 Gene

  • MicroRNA 759 2 3 5
  • Hsa-Mir-759 3

External Ids for MIR759 Gene

Previous GeneCards Identifiers for MIR759 Gene

  • GC00U929326
  • GC13P053385
  • GC13P034098

Summaries for MIR759 Gene

Entrez Gene Summary for MIR759 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR759 Gene

MIR759 (MicroRNA 759) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR759 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR759 Gene

Genomics for MIR759 Gene

GeneHancer (GH) Regulatory Elements for MIR759 Gene

Promoters and enhancers for MIR759 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH13I052809 Enhancer 0.9 ENCODE 550.8 -0.5 -549 0.2 ATF1 SMAD1 GLIS2 ZNF213 GATA2 ZNF143 ATF7 RUNX3 REST ZNF592 MIR759 GC13M052809 PPIAP26 LOC105370209 GC13M052802
GH13I052879 Enhancer 0.5 ENCODE 10.6 +70.6 70580 1.4 SP1 SCRT2 POU5F1 ATF7 ATF2 MIR759 CKAP2 PCDH8 GC13M052802
GH13I052640 Promoter 0.5 EPDnew 10.4 -169.3 -169264 0.1 HNRNPA1L2 TPTE2P2 MIR759 ENSG00000273723 ENSG00000273784
GH13I052762 Enhancer 0.2 FANTOM5 10.7 -47.3 -47269 0.3 MIR759 LOC105370209 CNMD
GH13I052779 Enhancer 0.2 FANTOM5 0.3 -30.9 -30859 0.1 PCDH8 HNRNPA1L2 LOC105370209 MIR759
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR759 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR759 Gene

Genomic Locations for MIR759 Gene
91 bases
Plus strand

Genomic View for MIR759 Gene

Genes around MIR759 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR759 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR759 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR759 Gene

Proteins for MIR759 Gene

Post-translational modifications for MIR759 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR759 Gene

Domains & Families for MIR759 Gene

Gene Families for MIR759 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR759: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR759 Gene

Function for MIR759 Gene

Phenotypes From GWAS Catalog for MIR759 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR759 Gene

Localization for MIR759 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR759 Gene

Pathways & Interactions for MIR759 Gene

SuperPathways for MIR759 Gene

No Data Available

Interacting Proteins for MIR759 Gene

Gene Ontology (GO) - Biological Process for MIR759 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR759 Gene

Drugs & Compounds for MIR759 Gene

No Compound Related Data Available

Transcripts for MIR759 Gene

mRNA/cDNA for MIR759 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR759 Gene

No ASD Table

Relevant External Links for MIR759 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR759 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR759 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR759 Gene:

genes like me logo Genes that share expression patterns with MIR759: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR759 Gene

Orthologs for MIR759 Gene

Evolution for MIR759 Gene

Gene Tree for MIR759 (if available)
Gene Tree for MIR759 (if available)

No data available for Orthologs for MIR759 Gene

Paralogs for MIR759 Gene

No data available for Paralogs for MIR759 Gene

Variants for MIR759 Gene

Sequence variations from dbSNP and Humsavar for MIR759 Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000408977 -- 52,808,817(+) C/T upstream_transcript_variant
rs1001278638 -- 52,809,582(+) G/A upstream_transcript_variant
rs1001306923 -- 52,809,400(+) G/A upstream_transcript_variant
rs1001337958 -- 52,809,087(+) A/G upstream_transcript_variant
rs1005948452 -- 52,808,695(+) GAGGTGGCTCTAGGAG/GAG upstream_transcript_variant

Additional Variant Information for MIR759 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR759 Gene

Disorders for MIR759 Gene

Additional Disease Information for MIR759

No disorders were found for MIR759 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR759 Gene

Publications for MIR759 Gene

  1. Susceptibility to chronic thromboembolic pulmonary hypertension may be conferred by miR-759 via its targeted interaction with polymorphic fibrinogen alpha gene. (PMID: 20677013) Chen Z … Kimura A (Human genetics 2010) 3 58
  2. miRNAminer: a tool for homologous microRNA gene search. (PMID: 18215311) Artzi S … Shomron N (BMC bioinformatics 2008) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  4. Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. (PMID: 16954537) Berezikov E … Cuppen E (Genome research 2006) 3 58

Products for MIR759 Gene

Sources for MIR759 Gene

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