microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7157 Gene

Subcategory (RNA class) for MIR7157 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR7157 Gene

  • MicroRNA 7157 2 3 5
  • MicroRNA Mir-7157 3
  • Hsa-Mir-7157 3
  • MIMAT0028224 51
  • MIMAT0028225 51
  • MI0023617 51
  • MIR7157 2

External Ids for MIR7157 Gene

Previous GeneCards Identifiers for MIR7157 Gene

  • GC02U902988

Summaries for MIR7157 Gene

Entrez Gene Summary for MIR7157 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7157 Gene

MIR7157 (MicroRNA 7157) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR7157 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7157 Gene

Genomics for MIR7157 Gene

GeneHancer (GH) Regulatory Elements for MIR7157 Gene

Promoters and enhancers for MIR7157 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J140580 Enhancer 0.7 Ensembl 0.4 +5.7 5684 0.8 ZSCAN5C TCF12 TRIM28 EP300 OSR2 WT1 TCF7L2 MAFF ZNF263 MAFK MIR7157 piR-37656-132
GH02J140657 Enhancer 0.6 Ensembl 0.2 -71.6 -71615 1 EP300 TCF12 GATA3 CEBPB FOS JUND ZNF843 BCL11B STAT3 PRDM6 ENSG00000236440 MIR7157
GH02J140643 Enhancer 0.5 ENCODE 0.2 -57.3 -57262 0.2 TCF12 FOS FOSL2 NR3C1 EP300 JUND FOXA1 CEBPB SP1 ENSG00000236440 MIR7157
GH02J140650 Enhancer 0.5 Ensembl 0.2 -64.2 -64216 0.2 TCF12 FOSL2 GATA2 NR3C1 FOXA1 SP1 ENSG00000236440 MIR7157
GH02J140648 Enhancer 0.4 Ensembl 0.2 -62.0 -62016 0.2 EP300 GATA3 FOXA1 ENSG00000236440 MIR7157
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7157 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7157 Gene

Genomic Locations for MIR7157 Gene
chr2:140,586,626-140,586,685
(GRCh38/hg38)
Size:
60 bases
Orientation:
Minus strand

Genomic View for MIR7157 Gene

Genes around MIR7157 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7157 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7157 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7157 Gene

Proteins for MIR7157 Gene

Post-translational modifications for MIR7157 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7157 Gene

Domains & Families for MIR7157 Gene

Gene Families for MIR7157 Gene

HGNC:
genes like me logo Genes that share domains with MIR7157: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7157 Gene

Function for MIR7157 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7157 Gene

Localization for MIR7157 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7157 Gene

Pathways & Interactions for MIR7157 Gene

PathCards logo

SuperPathways for MIR7157 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR7157 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR7157 Gene

Drugs & Compounds for MIR7157 Gene

No Compound Related Data Available

Transcripts for MIR7157 Gene

mRNA/cDNA for MIR7157 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7157 Gene

No ASD Table

Relevant External Links for MIR7157 Gene

GeneLoc Exon Structure for
MIR7157

Expression for MIR7157 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7157 Gene

Orthologs for MIR7157 Gene

Evolution for MIR7157 Gene

ENSEMBL:
Gene Tree for MIR7157 (if available)
TreeFam:
Gene Tree for MIR7157 (if available)

No data available for Orthologs for MIR7157 Gene

Paralogs for MIR7157 Gene

No data available for Paralogs for MIR7157 Gene

Variants for MIR7157 Gene

Additional dbSNP identifiers (rs#s) for MIR7157 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR7157 Gene

Variant ID Type Subtype PubMed ID
dgv229n21 CNV gain 19592680
nsv459529 CNV gain 19166990
nsv583192 CNV gain 21841781

Additional Variant Information for MIR7157 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7157

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR7157 Gene

Disorders for MIR7157 Gene

Additional Disease Information for MIR7157

No disorders were found for MIR7157 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7157 Gene

Publications for MIR7157 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR7157 Gene

Sources for MIR7157 Gene