microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7154 Gene

Subcategory (RNA class) for MIR7154 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR7154 Gene

  • MicroRNA 7154 2 3 5
  • Hsa-Mir-7154 2 3
  • MIR7154 2 5
  • MicroRNA Mir-7154 3
  • MIMAT0028218 50
  • MIMAT0028219 50
  • MI0023614 50

External Ids for MIR7154 Gene

Previous GeneCards Identifiers for MIR7154 Gene

  • GC11U902235

Summaries for MIR7154 Gene

Entrez Gene Summary for MIR7154 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7154 Gene

MIR7154 (MicroRNA 7154) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR7154 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7154 Gene

Genomics for MIR7154 Gene

Genomic Locations for MIR7154 Gene

Genomic Locations for MIR7154 Gene
chr11:45,691,704-45,691,776
(GRCh38/hg38)
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR7154 Gene

Genes around MIR7154 on UCSC Golden Path with GeneCards custom track
MIR7154 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR7154 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7154 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7154 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR7154 Gene

Proteins for MIR7154 Gene

Post-translational modifications for MIR7154 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7154 Gene

Domains & Families for MIR7154 Gene

Gene Families for MIR7154 Gene

HGNC:
genes like me logo Genes that share domains with MIR7154: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7154 Gene

Function for MIR7154 Gene

Phenotypes From GWAS Catalog for MIR7154 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7154 Gene

Localization for MIR7154 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7154 Gene

Pathways & Interactions for MIR7154 Gene

PathCards logo

SuperPathways for MIR7154 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR7154 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR7154 Gene

Drugs & Compounds for MIR7154 Gene

No Compound Related Data Available

Transcripts for MIR7154 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7154 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075E270_9606 precursor_RNA 73 4

HGNC: 49972,

RefSeq: NR_106976,

Ensembl: ENST00000620673 (view in UCSC) ,

miRBase: MI0023614,

URS000075D02B_9606 miRNA 23 2

RefSeq: NR_106976,

miRBase: MIMAT0028218,

URS000075A93E_9606 miRNA 20 2

RefSeq: NR_106976,

miRBase: MIMAT0028219,

MIR7154 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7154 Gene

No ASD Table

Relevant External Links for MIR7154 Gene

GeneLoc Exon Structure for
MIR7154

No data available for mRNA/cDNA for MIR7154 Gene

Expression for MIR7154 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7154 Gene

Orthologs for MIR7154 Gene

Evolution for MIR7154 Gene

ENSEMBL:
Gene Tree for MIR7154 (if available)
TreeFam:
Gene Tree for MIR7154 (if available)

No data available for Orthologs for MIR7154 Gene

Paralogs for MIR7154 Gene

No data available for Paralogs for MIR7154 Gene

Variants for MIR7154 Gene

Additional dbSNP identifiers (rs#s) for MIR7154 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR7154 Gene

Variant ID Type Subtype PubMed ID
nsv554199 CNV loss 21841781

Additional Variant Information for MIR7154 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7154

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR7154 Gene

Disorders for MIR7154 Gene

Additional Disease Information for MIR7154

No disorders were found for MIR7154 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7154 Gene

Publications for MIR7154 Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR7154 Gene

Sources for MIR7154 Gene