microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR7113 Gene

Data sources for MIR7113 Gene:

RNA type for MIR7113 Gene

miRNA

Aliases for MIR7113 Gene

External Ids for MIR7113 Gene

Previous GeneCards Identifiers for MIR7113 Gene

  • GC11U902226

Summaries for MIR7113 Gene

Entrez Gene Summary for MIR7113 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7113 Gene

MIR7113 (MicroRNA 7113) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Metabolism.

Additional gene information for MIR7113 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR7113 Gene

Genomics for MIR7113 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR7113 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J068026 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 0.7 -2.4 -2379 7.6 SP1 ZNF207 MYC IKZF1 JUND POLR2A ZNF10 BRCA1 ZIC2 CHD4 ENSG00000255306 NDUFS8 HSALNG0085209 ALDH3B1 PPP6R3 CHKA-DT TCIRG1 MIR4691 MIR7113 lnc-CHKA-3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7113 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR7113 Gene

Latest Assembly
chr11:68,032,864-68,032,922
(GRCh38/hg38)
Size:
59 bases
Orientation:
Plus strand

Previous Assembly
chr11:67,800,331-67,800,389
(GRCh37/hg19 by Entrez Gene)
Size:
59 bases
Orientation:
Plus strand

Genomic View for MIR7113 Gene

Genes around MIR7113 on UCSC Golden Path with GeneCards custom track
MIR7113 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR7113 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7113 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7113 Gene

Proteins for MIR7113 Gene

Post-translational modifications for MIR7113 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7113 Gene

Domains & Families for MIR7113 Gene

Gene Families for MIR7113 Gene

HGNC:
genes like me logo Genes that share domains with MIR7113: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7113 Gene

Function for MIR7113 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7113 Gene

Localization for MIR7113 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7113 Gene

Pathways & Interactions for MIR7113 Gene

genes like me logo Genes that share pathways with MIR7113: view

Gene Ontology (GO) - Biological Process for MIR7113 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR7113 Gene

Drugs & Compounds for MIR7113 Gene

No Compound Related Data Available

Transcripts for MIR7113 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7113 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075DBAA_9606 pre_miRNA 59 3

RefSeq: NR_106963,

Ensembl: ENST00000621222 (view in UCSC) ,

miRBase: MI0022964,

URS000075D451_9606 miRNA 23 2

RefSeq: NR_106963,

miRBase: MIMAT0028124,

URS00007599A0_9606 miRNA 21 2

RefSeq: NR_106963,

miRBase: MIMAT0028123,

MIR7113 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7113 Gene

No ASD Table

Relevant External Links for MIR7113 Gene

GeneLoc Exon Structure for
MIR7113

No data available for mRNA/cDNA for MIR7113 Gene

Expression for MIR7113 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7113 Gene

Orthologs for MIR7113 Gene

Evolution for MIR7113 Gene

ENSEMBL:
Gene Tree for MIR7113 (if available)
TreeFam:
Gene Tree for MIR7113 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR7113

No data available for Orthologs for MIR7113 Gene

Paralogs for MIR7113 Gene

No data available for Paralogs for MIR7113 Gene

Variants for MIR7113 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR7113 Gene

SNP ID Clinical significance and condition Chr 11 pos Variation AA Info Type
rs762778582 Likely Benign: not specified 68,032,912(+) C/T
NM_002496.4(NDUFS8):c.110-11C>T
NON_CODING_TRANSCRIPT_VARIANT,INTRON

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR7113 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR7113 Gene

Variant ID Type Subtype PubMed ID
dgv1221n100 CNV gain 25217958
dgv1981n54 CNV gain 21841781
dgv1983n54 CNV loss 21841781
esv2759835 CNV gain+loss 17122850
nsv468606 CNV gain 19166990
nsv468615 CNV loss 19166990
nsv469856 CNV gain 16826518
nsv469964 CNV loss 18288195
nsv555278 CNV loss 21841781
nsv555282 CNV loss 21841781
nsv825963 CNV gain 20364138
nsv8836 CNV gain 18304495
nsv951026 CNV deletion 24416366

Additional Variant Information for MIR7113 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7113
Leiden Open Variation Database (LOVD)
MIR7113

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7113 Gene

Disorders for MIR7113 Gene

Additional Disease Information for MIR7113

No disorders were found for MIR7113 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR7113 Gene

Publications for MIR7113 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR7113 Gene

Sources for MIR7113 Gene