Aliases for MIR7-3HG Gene

Subcategory (RNA class) for MIR7-3HG Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for MIR7-3HG Gene

  • MIR7-3 Host Gene 2 3 5
  • MIR7-3HG 2 5 165
  • PGSF1 2 3 4
  • Long Intergenic Non-Protein Coding RNA 306 2 3
  • MIR7-3 Host Gene (Non-Protein Coding) 2 3
  • NCRNA00306 3 4
  • Uc002mbe.2 2 3
  • LINC00306 3 4
  • C19orf30 3 4
  • Huh7 2 3
  • Putative Uncharacterized Protein Encoded By MIR7-3HG 4
  • Chromosome 19 Open Reading Frame 30 2
  • Pituitary Gland Specific Factor 1a 2
  • Pituitary Gland Specific Factor 1b 2
  • Pituitary Gland Specific Factor 1 3
  • Pituitary Gland-Specific Factor 1 4
  • Non-Protein Coding RNA 306 2
  • NONHSAG024540.2 91
  • NONHSAG024541.2 91
  • HSALNG0123415 164
  • HSALNG0123418 164
  • Lnc-FEM1A-2 165
  • PGSF1a 2
  • PGSF1b 2

External Ids for MIR7-3HG Gene

Previous HGNC Symbols for MIR7-3HG Gene

  • C19orf30
  • NCRNA00306
  • LINC00306

Previous GeneCards Identifiers for MIR7-3HG Gene

  • GC19P004771
  • GC19P004773
  • GC19P004775
  • GC19P004778
  • GC19P004777
  • GC19P004779
  • GC19P004789
  • GC19P004790
  • GC19P004774
  • GC19P004788
  • GC19P004780
  • GC19P004781
  • GC19P004782
  • GC19P004783
  • GC19P004784
  • GC19P004785
  • GC19P004786

Summaries for MIR7-3HG Gene

GeneCards Summary for MIR7-3HG Gene

MIR7-3HG (MIR7-3 Host Gene) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR7-3HG include Astrocytoma and Hepatocellular Carcinoma.

Rfam classification for MIR7-3HG Gene

Additional gene information for MIR7-3HG Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR7-3HG Gene

Genomics for MIR7-3HG Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR7-3HG Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7-3HG on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR7-3HG Gene

Genomic Locations for MIR7-3HG Gene
chr19:4,769,031-4,785,077
(GRCh38/hg38)
Size:
16,047 bases
Orientation:
Plus strand
chr19:4,769,117-4,772,568
(GRCh37/hg19)
Size:
3,452 bases
Orientation:
Plus strand

Genomic View for MIR7-3HG Gene

Genes around MIR7-3HG on UCSC Golden Path with GeneCards custom track
MIR7-3HG in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR7-3HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-3HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-3HG Gene

Proteins for MIR7-3HG Gene

  • Protein details for MIR7-3HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6C7-PGSF1_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by MIR7-3HG
    Protein Accession:
    Q8N6C7
    Secondary Accessions:
    • D6W630
    • Q17RJ9
    • Q8N6C6

    Protein attributes for MIR7-3HG Gene

    Size:
    128 amino acids
    Molecular mass:
    14321 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • [Isoform 2]: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

    Alternative splice isoforms for MIR7-3HG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MIR7-3HG Gene

Post-translational modifications for MIR7-3HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-3HG Gene

Domains & Families for MIR7-3HG Gene

Gene Families for MIR7-3HG Gene

Protein Domains for MIR7-3HG Gene

ProtoNet:

Suggested Antigen Peptide Sequences for MIR7-3HG Gene

GenScript: Design optimal peptide antigens:
  • Pituitary gland-specific factor 1 (PGSF1_HUMAN)
genes like me logo Genes that share domains with MIR7-3HG: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7-3HG Gene

Function for MIR7-3HG Gene

Phenotypes From GWAS Catalog for MIR7-3HG Gene

Phenotypes for MIR7-3HG Gene

genes like me logo Genes that share phenotypes with MIR7-3HG: view

Animal Model Products

CRISPR Products

miRNA for MIR7-3HG Gene

miRTarBase miRNAs that target MIR7-3HG

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR7-3HG Gene

Localization for MIR7-3HG Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR7-3HG gene
Compartment Confidence
nucleus 3
plasma membrane 2
extracellular 2
cytoskeleton 2
mitochondrion 2
endoplasmic reticulum 2
endosome 2
cytosol 2
lysosome 2
golgi apparatus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7-3HG Gene

Pathways & Interactions for MIR7-3HG Gene

PathCards logo

SuperPathways for MIR7-3HG Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR7-3HG Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR7-3HG Gene

Drugs & Compounds for MIR7-3HG Gene

No Compound Related Data Available

Transcripts for MIR7-3HG Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR7-3HG Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000026FEB_9606 lncRNA 865 4

Ensembl: ENST00000588758 (view in UCSC) ,

LncBook: HSALNT0254887,

LNCipedia: MIR7-3HG:11,

NONCODE: NONHSAT060649.2,

URS000075D132_9606 lncRNA 768 4

HGNC: 30049,

RefSeq: NR_027148,

LNCipedia: MIR7-3HG:2,

NONCODE: NONHSAT060641.2,

URS0000026EFF_9606 lncRNA 725 4

Ensembl: ENST00000592709 (view in UCSC) ,

LncBook: HSALNT0254879,

LNCipedia: MIR7-3HG:5,

NONCODE: NONHSAT060643.2,

URS00000F434B_9606 lncRNA 587 3

Ensembl: ENST00000589639 (view in UCSC) ,

LNCipedia: MIR7-3HG:8,

NONCODE: NONHSAT060646.2,

URS0000EF2EA7_9606 lncRNA 1482 1

Ensembl: ENST00000663804 (view in UCSC) ,

MIR7-3HG in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR7-3HG Gene

1 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MIR7-3HG

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3HG Gene

No ASD Table

Relevant External Links for MIR7-3HG Gene

GeneLoc Exon Structure for
MIR7-3HG

Expression for MIR7-3HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR7-3HG Gene

mRNA differential expression in normal tissues according to GTEx for MIR7-3HG Gene

This gene is overexpressed in Pituitary (x48.2).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR7-3HG

SOURCE GeneReport for Unigene cluster for MIR7-3HG Gene:

Hs.326728

mRNA Expression by UniProt/SwissProt for MIR7-3HG Gene:

Q8N6C7-PGSF1_HUMAN
Tissue specificity: High expression in pituitary gland and weak in pancreas.

Evidence on tissue expression from TISSUES for MIR7-3HG Gene

  • Liver(3.2)
  • Kidney(2.4)
  • Blood(2.3)
  • Intestine(2.2)
  • Skin(2.1)
genes like me logo Genes that share expression patterns with MIR7-3HG: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7-3HG Gene

Orthologs for MIR7-3HG Gene

Evolution for MIR7-3HG Gene

ENSEMBL:
Gene Tree for MIR7-3HG (if available)
TreeFam:
Gene Tree for MIR7-3HG (if available)

No data available for Orthologs for MIR7-3HG Gene

Paralogs for MIR7-3HG Gene

No data available for Paralogs for MIR7-3HG Gene

Variants for MIR7-3HG Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR7-3HG Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs11878617 - p.Arg73Ser
rs3760955 - p.His91Gln

Additional dbSNP identifiers (rs#s) for MIR7-3HG Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR7-3HG Gene

Variant ID Type Subtype PubMed ID
nsv1062709 CNV loss 25217958
nsv578452 CNV loss 21841781

Additional Variant Information for MIR7-3HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7-3HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-3HG Gene

Disorders for MIR7-3HG Gene

MalaCards: The human disease database

(4) MalaCards diseases for MIR7-3HG Gene - From: LncRNADisease and DISEASES

- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with MIR7-3HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7-3HG Gene

Publications for MIR7-3HG Gene

  1. Expression profile of active genes in the human pituitary gland. (PMID: 11854097) Tanaka S … Amino N (Journal of molecular endocrinology 2002) 2 3 4 23
  2. Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. (PMID: 23643933) Yang H … Wan YJ (Biochemical pharmacology 2013) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  4. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. (PMID: 28059583) Capizzi M … Cecconi F (Autophagy 2017) 3
  5. Inhibition of miR-7 promotes angiogenesis in human umbilical vein endothelial cells by upregulating VEGF via KLF4. (PMID: 27431648) Li YZ … Liu WC (Oncology reports 2016) 3

Products for MIR7-3HG Gene

Sources for MIR7-3HG Gene