Aliases for MIR7-3HG Gene

Subcategory (RNA class) for MIR7-3HG Gene

lncRNA

Quality Score for this RNA gene is

15

Aliases for MIR7-3HG Gene

  • MIR7-3 Host Gene 2 3 5
  • Long Intergenic Non-Protein Coding RNA 306 2 3
  • MIR7-3 Host Gene (Non-Protein Coding) 2 3
  • NCRNA00306 3 4
  • LINC00306 3 4
  • C19orf30 3 4
  • MIR7-3HG 2 170
  • PGSF1 3 4
  • Putative Uncharacterized Protein Encoded By MIR7-3HG 4
  • Chromosome 19 Open Reading Frame 30 2
  • Pituitary Gland Specific Factor 1a 2
  • Pituitary Gland Specific Factor 1b 2
  • Pituitary Gland Specific Factor 1 3
  • Pituitary Gland-Specific Factor 1 4
  • Non-Protein Coding RNA 306 2
  • HSALNG0123415 169
  • NONHSAG024540 94
  • Uc002mbe.2 3
  • Huh7 3

External Ids for MIR7-3HG Gene

Previous HGNC Symbols for MIR7-3HG Gene

  • C19orf30
  • NCRNA00306
  • LINC00306

Previous GeneCards Identifiers for MIR7-3HG Gene

  • GC19P004771
  • GC19P004773
  • GC19P004775
  • GC19P004778
  • GC19P004777
  • GC19P004779
  • GC19P004789
  • GC19P004790
  • GC19P004780
  • GC19P004781
  • GC19P004782
  • GC19P004783
  • GC19P004784
  • GC19P004785
  • GC19P004786
  • GC19P004788

Summaries for MIR7-3HG Gene

GeneCards Summary for MIR7-3HG Gene

MIR7-3HG (MIR7-3 Host Gene) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MIR7-3HG include Hepatocellular Carcinoma and Endocrine Gland Cancer.

Rfam classification for MIR7-3HG Gene

Additional gene information for MIR7-3HG Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR7-3HG Gene

Genomics for MIR7-3HG Gene

GeneHancer (GH) Regulatory Elements for MIR7-3HG Gene

Promoters and enhancers for MIR7-3HG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J004770 Promoter/Enhancer 1.4 Ensembl ENCODE 756 +0.8 769 1.6 E2F8 SIN3A ZNF24 ZBTB40 SREBF1 ZBTB6 MLX SMARCE1 RBPJ HDAC2 MIR7-3HG MIR7-3 ENSG00000267030 SAFB ENSG00000267769 YJU2 ENSG00000268670 HDGFL2 PIAS4 SAFB2
GH19J004828 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 11.5 +62.1 62135 4.6 ZNF785 ZBTB40 RBPJ SMARCE1 POLR2A ETV6 ELF1 RELA L3MBTL2 RAD21 TICAM1 RF00017-2761 SAFB DPP9-AS1 DUS3L PLIN3 DAPK3 ARRDC5 FEM1A MIR7-3
GH19J004759 Promoter/Enhancer 1.4 ENCODE CraniofacialAtlas 12.6 -9.3 -9342 1.4 SP1 RBPJ USF2 MIXL1 NFYC MAX MNT ZKSCAN8 ZNF148 ELF3 CHAF1A MIR7-3HG ENSG00000268536 lnc-FEM1A-3
GH19J004690 Enhancer 1.1 Ensembl ENCODE dbSUPER 11.8 -74.8 -74830 8 ZBTB40 FOXA1 USF2 ZNF121 NFIB SP1 MAFK SP7 ZIC2 RXRA MYDGF DPP9 MIR7-3HG MIR7-3 FEM1A SAFB2 ENSG00000287884 LOC105372250
GH19J004744 Enhancer 0.9 Ensembl ENCODE 13.5 -24.1 -24101 1.5 SMARCE1 MLLT1 SP7 SMARCA4 PRDM1 EGR1 FOSL2 IKZF1 REST PRDM10 MIR7-3HG MIR7-3 FEM1A DPP9 PLIN3 lnc-FEM1A-3 piR-55985-086
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7-3HG on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7-3HG Gene

Genomic Locations for MIR7-3HG Gene
chr19:4,769,031-4,785,077
(GRCh38/hg38)
Size:
16,047 bases
Orientation:
Plus strand
chr19:4,769,117-4,772,568
(GRCh37/hg19)
Size:
3,452 bases
Orientation:
Plus strand

Genomic View for MIR7-3HG Gene

Genes around MIR7-3HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-3HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-3HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-3HG Gene

Proteins for MIR7-3HG Gene

  • Protein details for MIR7-3HG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6C7-PGSF1_HUMAN
    Recommended name:
    Putative uncharacterized protein encoded by MIR7-3HG
    Protein Accession:
    Q8N6C7
    Secondary Accessions:
    • D6W630
    • Q17RJ9
    • Q8N6C6

    Protein attributes for MIR7-3HG Gene

    Size:
    128 amino acids
    Molecular mass:
    14321 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MIR7-3HG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MIR7-3HG Gene

Post-translational modifications for MIR7-3HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-3HG Gene

Domains & Families for MIR7-3HG Gene

Gene Families for MIR7-3HG Gene

Protein Domains for MIR7-3HG Gene

ProtoNet:

Suggested Antigen Peptide Sequences for MIR7-3HG Gene

GenScript: Design optimal peptide antigens:
  • Pituitary gland-specific factor 1 (PGSF1_HUMAN)
genes like me logo Genes that share domains with MIR7-3HG: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR7-3HG Gene

Function for MIR7-3HG Gene

Phenotypes From GWAS Catalog for MIR7-3HG Gene

genes like me logo Genes that share phenotypes with MIR7-3HG: view

Animal Model Products

CRISPR Products

miRNA for MIR7-3HG Gene

miRTarBase miRNAs that target MIR7-3HG

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MIR7-3HG Gene

Localization for MIR7-3HG Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MIR7-3HG gene
Compartment Confidence
extracellular 2
mitochondrion 2
nucleus 2
plasma membrane 1
cytoskeleton 1
endoplasmic reticulum 1
endosome 1
cytosol 1
lysosome 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR7-3HG Gene

Pathways & Interactions for MIR7-3HG Gene

PathCards logo

SuperPathways for MIR7-3HG Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR7-3HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR7-3HG Gene

Drugs & Compounds for MIR7-3HG Gene

No Compound Related Data Available

Transcripts for MIR7-3HG Gene

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3HG Gene

No ASD Table

Relevant External Links for MIR7-3HG Gene

GeneLoc Exon Structure for
MIR7-3HG
ECgene alternative splicing isoforms for
MIR7-3HG

Expression for MIR7-3HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR7-3HG Gene

mRNA differential expression in normal tissues according to GTEx for MIR7-3HG Gene

This gene is overexpressed in Pituitary (x48.2).

SOURCE GeneReport for Unigene cluster for MIR7-3HG Gene:

Hs.326728

mRNA Expression by UniProt/SwissProt for MIR7-3HG Gene:

Q8N6C7-PGSF1_HUMAN
Tissue specificity: High expression in pituitary gland and weak in pancreas.

Evidence on tissue expression from TISSUES for MIR7-3HG Gene

  • Liver(3.5)
genes like me logo Genes that share expression patterns with MIR7-3HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7-3HG Gene

Orthologs for MIR7-3HG Gene

Evolution for MIR7-3HG Gene

ENSEMBL:
Gene Tree for MIR7-3HG (if available)
TreeFam:
Gene Tree for MIR7-3HG (if available)

No data available for Orthologs for MIR7-3HG Gene

Paralogs for MIR7-3HG Gene

No data available for Paralogs for MIR7-3HG Gene

Variants for MIR7-3HG Gene

Sequence variations from dbSNP and Humsavar for MIR7-3HG Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000538097 -- 4,771,641(+) T/C intron_variant
rs1000914634 -- 4,767,509(+) C/T upstream_transcript_variant
rs1001444042 -- 4,768,952(+) C/T upstream_transcript_variant
rs1001647487 -- 4,773,036(+) G/C downstream_transcript_variant
rs1001791878 -- 4,769,179(+) A/G non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR7-3HG Gene

Variant ID Type Subtype PubMed ID
nsv1062709 CNV loss 25217958
nsv578452 CNV loss 21841781

Additional Variant Information for MIR7-3HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR7-3HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-3HG Gene

Disorders for MIR7-3HG Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR7-3HG Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
hepatocellular carcinoma
  • hcc
endocrine gland cancer
  • endocrine neoplasm
glycine n-methyltransferase deficiency
  • gnmt deficiency
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR7-3HG

genes like me logo Genes that share disorders with MIR7-3HG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7-3HG Gene

Publications for MIR7-3HG Gene

  1. Expression profile of active genes in the human pituitary gland. (PMID: 11854097) Tanaka S … Amino N (Journal of molecular endocrinology 2002) 2 3 4 23 56
  2. Induction of the liver cancer-down-regulated long noncoding RNA uc002mbe.2 mediates trichostatin-induced apoptosis of liver cancer cells. (PMID: 23643933) Yang H … Wan YJ (Biochemical pharmacology 2013) 2 3 56
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
  4. MIR7-3HG, a MYC-dependent modulator of cell proliferation, inhibits autophagy by a regulatory loop involving AMBRA1. (PMID: 28059583) Capizzi M … Cecconi F (Autophagy 2017) 3 56
  5. Inhibition of miR-7 promotes angiogenesis in human umbilical vein endothelial cells by upregulating VEGF via KLF4. (PMID: 27431648) Li YZ … Liu WC (Oncology reports 2016) 3 56

Products for MIR7-3HG Gene

Sources for MIR7-3HG Gene