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Aliases for MIR7-3 Gene

Subcategory (RNA class) for MIR7-3 Gene


Quality Score for this RNA gene is


Aliases for MIR7-3 Gene

  • MicroRNA 7-3 2 3 5
  • Hsa-Mir-7-3 3
  • MiR-7-5p 3
  • Mir-7-3 3
  • MIRN7-3 3

External Ids for MIR7-3 Gene

ORGUL Members for MIR7-3 Gene

Previous HGNC Symbols for MIR7-3 Gene

  • MIRN7-3

Previous GeneCards Identifiers for MIR7-3 Gene

  • GC19P004726

Summaries for MIR7-3 Gene

Entrez Gene Summary for MIR7-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR7-3 Gene

MIR7-3 (MicroRNA 7-3) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR7-3 include Pancreatitis, Hereditary and Pituitary Adenoma. Among its related pathways are MicroRNAs in cancer.

Additional gene information for MIR7-3 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR7-3 Gene

Genomics for MIR7-3 Gene

GeneHancer (GH) Regulatory Elements for MIR7-3 Gene

Promoters and enhancers for MIR7-3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J004769 Enhancer 1 ENCODE 550.7 -1.0 -976 0.2 NR2F6 MNT SMARCE1 ZKSCAN8 HCFC1 MLLT1 GTF2F1 ZNF24 TEAD4 SMARCA4 MIR7-3HG GC19P004774 GC19P004787 MIR7-3 ENSG00000267030 ENSG00000267769 SAFB YJU2 PTPRS DPP9-AS1
GH19J004770 Enhancer 0.6 ENCODE 550.7 -1.6 -1586 0.2 BCL6B SP1 KLF14 POLR2A SP2 ATF2 MYNN ZFHX2 ZNF143 YY2 GC19P004774 GC19P004787 MIR7-3 MIR7-3HG GC19M004737 TRV-CAC3-1
GH19J004828 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 11.5 +60.5 60496 4.6 SPI1 SP1 ZKSCAN8 ZFX IRF5 MLLT1 ZNF687 L3MBTL2 ZSCAN21 SMARCA4 TICAM1 GC19P004832 SAFB2 PLIN3 SAFB ARRDC5 FEM1A MIR7-3 MIR7-3HG SNRPEP4
GH19J004744 Enhancer 1 Ensembl ENCODE 13.5 -25.6 -25573 1.1 MLLT1 PRDM1 SMARCA4 IKZF1 ZNF600 FOSL2 SP7 REST PRDM10 POLR2A MIR7-3HG MIR7-3 FEM1A DPP9 PLIN3 GC19M004737 TRV-CAC3-1
GH19J004741 Enhancer 0.6 ENCODE 13.5 -28.0 -27956 1.4 ZNF473 ZIC2 POLR2A ZSCAN4 MNT ZBTB48 RCOR1 ZFHX2 GLIS1 ZNF398 MIR7-3 MIR7-3HG FEM1A HDGFL2 PIAS4 PLIN3 TRV-CAC3-1 GC19M004737
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR7-3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR7-3 Gene

Genomic Locations for MIR7-3 Gene
110 bases
Plus strand
110 bases
Plus strand

Genomic View for MIR7-3 Gene

Genes around MIR7-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR7-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR7-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR7-3 Gene

Proteins for MIR7-3 Gene

Post-translational modifications for MIR7-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR7-3 Gene

Domains & Families for MIR7-3 Gene

Gene Families for MIR7-3 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR7-3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR7-3 Gene

Function for MIR7-3 Gene

Phenotypes From GWAS Catalog for MIR7-3 Gene

Gene Ontology (GO) - Molecular Function for MIR7-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 27431648
genes like me logo Genes that share ontologies with MIR7-3: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR7-3 Gene

Localization for MIR7-3 Gene

Gene Ontology (GO) - Cellular Components for MIR7-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 18766170
GO:0035068 micro-ribonucleoprotein complex IEA --
genes like me logo Genes that share ontologies with MIR7-3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR7-3 Gene

Pathways & Interactions for MIR7-3 Gene

SuperPathways for MIR7-3 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR7-3: view

Pathways by source for MIR7-3 Gene

1 KEGG pathway for MIR7-3 Gene

Interacting Proteins for MIR7-3 Gene

Gene Ontology (GO) - Biological Process for MIR7-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA,IEA --
GO:1903671 negative regulation of sprouting angiogenesis IMP 27431648
genes like me logo Genes that share ontologies with MIR7-3: view

No data available for SIGNOR curated interactions for MIR7-3 Gene

Drugs & Compounds for MIR7-3 Gene

No Compound Related Data Available

Transcripts for MIR7-3 Gene

mRNA/cDNA for MIR7-3 Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(2) RNA Central transcripts :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR7-3 Gene

No ASD Table

Relevant External Links for MIR7-3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR7-3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR7-3 Gene

genes like me logo Genes that share expression patterns with MIR7-3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR7-3 Gene

Orthologs for MIR7-3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR7-3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-7-3 35
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-7-3 35
  • 84 (a)
(Mus musculus)
Mammalia Mir7b 35
  • 73 (a)
(Bos Taurus)
Mammalia bta-mir-7-3 35
  • 70 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 68 (a)
(Gallus gallus)
Aves gga-mir-7-3 35
  • 76 (a)
(Danio rerio)
Actinopterygii CR933818.1 35
  • 63 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-7 35
  • 51 (a)
Species where no ortholog for MIR7-3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR7-3 Gene

Gene Tree for MIR7-3 (if available)
Gene Tree for MIR7-3 (if available)

Paralogs for MIR7-3 Gene

No data available for Paralogs for MIR7-3 Gene

Variants for MIR7-3 Gene

Sequence variations from dbSNP and Humsavar for MIR7-3 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1001444042 -- 4,768,952(+) C/T upstream_transcript_variant
rs1001791878 -- 4,769,179(+) A/G upstream_transcript_variant
rs1003848995 -- 4,770,939(+) A/G downstream_transcript_variant
rs1004263760 -- 4,771,122(+) A/T downstream_transcript_variant
rs1005509947 -- 4,769,906(+) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR7-3 Gene

Variant ID Type Subtype PubMed ID
nsv1062709 CNV loss 25217958
nsv578452 CNV loss 21841781

Additional Variant Information for MIR7-3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR7-3 Gene

Disorders for MIR7-3 Gene

MalaCards: The human disease database

(3) MalaCards diseases for MIR7-3 Gene - From: miR2Disease

Disorder Aliases PubMed IDs
pancreatitis, hereditary
  • cp
pituitary adenoma
  • adenoma of the pituitary gland
colorectal cancer
  • crc
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR7-3

genes like me logo Genes that share disorders with MIR7-3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR7-3 Gene

Publications for MIR7-3 Gene

  1. TWEAK-stimulated macrophages inhibit metastasis of epithelial ovarian cancer via exosomal shuttling of microRNA. (PMID: 28216373) Hu Y … Qiu L (Cancer letters 2017) 3 58
  2. A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis. (PMID: 28431233) Treiber T … Meister G (Molecular cell 2017) 3 58
  3. microRNA-7 impairs autophagy-derived pools of glucose to suppress pancreatic cancer progression. (PMID: 28450156) Gu DN … Tian L (Cancer letters 2017) 3 58
  4. Differentiation of Human-Induced Pluripotent Stem Cells Into Insulin-Producing Clusters by MicroRNA-7. (PMID: 26103160) Shaer A … Dehghan S (Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 2016) 3 58
  5. Identification of a Novel Toll-like Receptor 7 Endogenous Ligand in Rheumatoid Arthritis Synovial Fluid That Can Provoke Arthritic Joint Inflammation. (PMID: 26662519) Kim SJ … Shahrara S (Arthritis & rheumatology (Hoboken, N.J.) 2016) 3 58

Products for MIR7-3 Gene

Sources for MIR7-3 Gene

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