microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6888 Gene

Subcategory (RNA class) for MIR6888 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR6888 Gene

  • MicroRNA 6888 2 3 5
  • MicroRNA Mir-6888 3
  • Hsa-Mir-6888 3
  • MIMAT0027676 51
  • MIMAT0027677 51
  • MI0022735 51
  • MIR6888 2

External Ids for MIR6888 Gene

Previous GeneCards Identifiers for MIR6888 Gene

  • GC02U903010

Summaries for MIR6888 Gene

Entrez Gene Summary for MIR6888 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6888 Gene

MIR6888 (MicroRNA 6888) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6888 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6888 Gene

Genomics for MIR6888 Gene

GeneHancer (GH) Regulatory Elements for MIR6888 Gene

Promoters and enhancers for MIR6888 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J159184 Enhancer 1 Ensembl ENCODE dbSUPER 500.7 -1.8 -1765 1.3 CTCF REST RAD21 SMC3 NR3C1 BATF POU2F2 EBF1 PAX5 IKZF1 MIR6888 PLA2R1 ENSG00000226266 HSALNG0019901 TANC1
GH02J159186 Enhancer 0.7 Ensembl dbSUPER 500.7 +1.0 966 2.4 CTBP1 MXI1 GATA3 NR2F2 BATF FOS RCOR1 GATA2 JUNB ZNF217 MIR6888 OR7E89P WDSUB1 LOC105373716 TANC1
GH02J159185 Enhancer 0.7 ENCODE dbSUPER 500.7 -0.8 -830 0.2 BATF EBF1 JUNB IKZF1 MTA3 PAX5 EED BCLAF1 RUNX3 MIR6888 HSALNG0019901 TANC1
GH02J159183 Enhancer 0.7 Ensembl dbSUPER 0.7 -3.2 -3234 0.4 ZNF217 KLF4 CTBP1 PKNOX1 RCOR1 GATA3 E2F1 ZNF687 TARDBP NCOA3 WDSUB1 MIR6888 HSALNG0019901 TANC1
GH02J159199 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +15.2 15157 4.4 JUND FOS RCOR1 BCL11A RELA CREB1 FOXA2 NFIC POLR2A NFE2 WDSUB1 MIR6888 LOC105373716 TANC1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6888 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6888 Gene

Genomic Locations for MIR6888 Gene
chr2:159,186,835-159,186,901
(GRCh38/hg38)
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR6888 Gene

Genes around MIR6888 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6888 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6888 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6888 Gene

Proteins for MIR6888 Gene

Post-translational modifications for MIR6888 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6888 Gene

Domains & Families for MIR6888 Gene

Gene Families for MIR6888 Gene

HGNC:
genes like me logo Genes that share domains with MIR6888: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6888 Gene

Function for MIR6888 Gene

Phenotypes From GWAS Catalog for MIR6888 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6888 Gene

Localization for MIR6888 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6888 Gene

Pathways & Interactions for MIR6888 Gene

PathCards logo

SuperPathways for MIR6888 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR6888 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6888 Gene

Drugs & Compounds for MIR6888 Gene

No Compound Related Data Available

Transcripts for MIR6888 Gene

mRNA/cDNA for MIR6888 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6888 Gene

No ASD Table

Relevant External Links for MIR6888 Gene

GeneLoc Exon Structure for
MIR6888

Expression for MIR6888 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6888 Gene

Orthologs for MIR6888 Gene

Evolution for MIR6888 Gene

ENSEMBL:
Gene Tree for MIR6888 (if available)
TreeFam:
Gene Tree for MIR6888 (if available)

No data available for Orthologs for MIR6888 Gene

Paralogs for MIR6888 Gene

No data available for Paralogs for MIR6888 Gene

Variants for MIR6888 Gene

Additional dbSNP identifiers (rs#s) for MIR6888 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6888 Gene

Variant ID Type Subtype PubMed ID
dgv4096n100 CNV gain 25217958
esv3593110 CNV loss 21293372
nsv1008665 CNV gain 25217958
nsv1010774 CNV gain 25217958
nsv1011598 CNV gain 25217958

Additional Variant Information for MIR6888 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6888

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6888 Gene

Disorders for MIR6888 Gene

Additional Disease Information for MIR6888

No disorders were found for MIR6888 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6888 Gene

Publications for MIR6888 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6888 Gene

Sources for MIR6888 Gene