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Aliases for MIR6886 Gene

Subcategory (RNA class) for MIR6886 Gene


Quality Score for this RNA gene is


Aliases for MIR6886 Gene

  • MicroRNA 6886 2 3 5
  • MicroRNA Mir-6886 3
  • Hsa-Mir-6886 3

External Ids for MIR6886 Gene

Previous GeneCards Identifiers for MIR6886 Gene

  • GC19U901811

Summaries for MIR6886 Gene

Entrez Gene Summary for MIR6886 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6886 Gene

MIR6886 (MicroRNA 6886) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6886 include Hypercholesterolemia, Familial. Among its related pathways are Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation and Vesicle-mediated transport.

Additional gene information for MIR6886 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6886 Gene

Genomics for MIR6886 Gene

GeneHancer (GH) Regulatory Elements for MIR6886 Gene

Promoters and enhancers for MIR6886 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J011114 Enhancer 0.7 dbSUPER 600.7 +0.9 857 0.4 SP1 POLR2A RXRA ZNF692 ZNF316 JUND NR2F2 ZFP69B SIN3A SUPT5H MIR6886 SPC24 LDLR
GH19J011111 Enhancer 0.4 dbSUPER 600.7 -1.8 -1763 0.5 POLR2A SUPT5H SMAD5 MIR6886 LDLR
GH19J011113 Enhancer 0.4 dbSUPER 600.7 +0.0 4 0.9 POLR2A SUPT5H MIR6886 TMEM205 LDLR SPC24
GH19J011086 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.3 -21.1 -21104 11 SP1 ZFX ZNF652 ELF3 MNT CBFA2T2 NKRF POLR2A MLLT1 ZNF121 LDLR ILF3 ZNF491 ZNF844 ZNF441 ZNF627 ZNF823 KRI1 ZNF788P C19orf38
GH19J011157 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 0.3 +41.9 41859 6.4 CC2D1A ZFX SP1 ELF3 ZNF148 NKRF POLR2A MLLT1 CEBPG GTF2F1 SPC24 KRI1 ILF3 TIMM29 ZNF20 ZNF700 ZNF627 ZNF433 ZNF878 ZNF763
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6886 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6886 Gene

Genomic Locations for MIR6886 Gene
61 bases
Plus strand

Genomic View for MIR6886 Gene

Genes around MIR6886 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6886 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6886 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6886 Gene

Proteins for MIR6886 Gene

Post-translational modifications for MIR6886 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6886 Gene

Domains & Families for MIR6886 Gene

Gene Families for MIR6886 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6886: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6886 Gene

Function for MIR6886 Gene

Phenotypes From GWAS Catalog for MIR6886 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6886 Gene

Localization for MIR6886 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6886 Gene

Drugs & Compounds for MIR6886 Gene

No Compound Related Data Available

Transcripts for MIR6886 Gene

mRNA/cDNA for MIR6886 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6886 Gene

No ASD Table

Relevant External Links for MIR6886 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR6886 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6886 Gene:

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6886 Gene

Orthologs for MIR6886 Gene

Evolution for MIR6886 Gene

Gene Tree for MIR6886 (if available)
Gene Tree for MIR6886 (if available)

No data available for Orthologs for MIR6886 Gene

Paralogs for MIR6886 Gene

No data available for Paralogs for MIR6886 Gene

Variants for MIR6886 Gene

Sequence variations from dbSNP and Humsavar for MIR6886 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1003723 benign, Familial hypercholesterolemia 11,113,505(+) C/A/T non_coding_transcript_variant
rs1057516128 likely-pathogenic, Familial hypercholesterolemia 11,113,584(+) A/G downstream_transcript_variant
rs1057519667 pathogenic, Familial hypercholesterolemia 11,113,277(+) GG/G upstream_transcript_variant
rs1057519668 likely-pathogenic, Familial hypercholesterolemia 11,113,296(+) T/C upstream_transcript_variant
rs1057519669 likely-pathogenic, Familial hypercholesterolemia 11,113,347(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6886 Gene

Variant ID Type Subtype PubMed ID
nsv470126 CNV loss 18288195
nsv833751 CNV loss 17160897

Additional Variant Information for MIR6886 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6886 Gene

Disorders for MIR6886 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6886 Gene - From: GeneCards

Disorder Aliases PubMed IDs
hypercholesterolemia, familial
  • fhc; fh
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6886

genes like me logo Genes that share disorders with MIR6886: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6886 Gene

Publications for MIR6886 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6886 Gene

Sources for MIR6886 Gene

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