microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6880 Gene

Data sources for MIR6880 Gene:

Subcategory (RNA class) for MIR6880 Gene

miRNA

Aliases for MIR6880 Gene

External Ids for MIR6880 Gene

Previous GeneCards Identifiers for MIR6880 Gene

  • GC12U901975

Summaries for MIR6880 Gene

Entrez Gene Summary for MIR6880 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6880 Gene

MIR6880 (MicroRNA 6880) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6880 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6880 Gene

Genomics for MIR6880 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6880 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J124338 Enhancer 0.5 FANTOM5 250.7 -1.4 -1399 0.3 SMC3 CTCF EGR2 ZFHX2 MIR6880 RFLNA HSALNG0094808 NCOR2
GH12J124336 Enhancer 0.4 Ensembl dbSUPER 250.7 +0.2 241 0.4 EGR2 MIR6880 lnc-CCDC92-4 HSALNG0094808 NCOR2 RFLNA
GH12J124339 Enhancer 0.3 dbSUPER 0.7 -3.0 -2982 1 EGR2 ZFHX2 HSALNG0094808 MIR6880 NCOR2 RFLNA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6880 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6880 Gene

Latest Assembly
chr12:124,337,181-124,337,242
(GRCh38/hg38)
Size:
62 bases
Orientation:
Minus strand

Previous Assembly
chr12:124,821,727-124,821,788
(GRCh37/hg19 by Entrez Gene)
Size:
62 bases
Orientation:
Minus strand

Genomic View for MIR6880 Gene

Genes around MIR6880 on UCSC Golden Path with GeneCards custom track
MIR6880 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6880 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6880 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6880 Gene

Proteins for MIR6880 Gene

Post-translational modifications for MIR6880 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6880 Gene

Domains & Families for MIR6880 Gene

Gene Families for MIR6880 Gene

HGNC:
genes like me logo Genes that share domains with MIR6880: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6880 Gene

Function for MIR6880 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6880 Gene

Localization for MIR6880 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6880 Gene

Pathways & Interactions for MIR6880 Gene

PathCards logo

SuperPathways for MIR6880 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6880 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6880 Gene

Drugs & Compounds for MIR6880 Gene

No Compound Related Data Available

Transcripts for MIR6880 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6880 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C131_9606 precursor_RNA 62 3

RefSeq: NR_106940,

Ensembl: ENST00000622851 (view in UCSC) ,

miRBase: MI0022727,

URS000075EE40_9606 miRNA 22 2

RefSeq: NR_106940,

miRBase: MIMAT0027660,

URS000075CCC6_9606 miRNA 21 2

RefSeq: NR_106940,

miRBase: MIMAT0027661,

MIR6880 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6880 Gene

No ASD Table

Relevant External Links for MIR6880 Gene

GeneLoc Exon Structure for
MIR6880

No data available for mRNA/cDNA for MIR6880 Gene

Expression for MIR6880 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6880 Gene

Orthologs for MIR6880 Gene

Evolution for MIR6880 Gene

ENSEMBL:
Gene Tree for MIR6880 (if available)
TreeFam:
Gene Tree for MIR6880 (if available)

No data available for Orthologs for MIR6880 Gene

Paralogs for MIR6880 Gene

No data available for Paralogs for MIR6880 Gene

Variants for MIR6880 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6880 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR6880 Gene

Variant ID Type Subtype PubMed ID
esv3631010 CNV gain 21293372
esv3631011 CNV gain 21293372
esv3631012 CNV gain 21293372
nsv470322 CNV loss 18288195
nsv560540 CNV loss 21841781
nsv818930 CNV gain 17921354
nsv832535 CNV gain 17160897
nsv916 CNV insertion 18451855
nsv952500 CNV deletion 24416366

Additional Variant Information for MIR6880 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6880

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6880 Gene

Disorders for MIR6880 Gene

Additional Disease Information for MIR6880

No disorders were found for MIR6880 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6880 Gene

Publications for MIR6880 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6880 Gene

Sources for MIR6880 Gene