microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6866 Gene

Subcategory (RNA class) for MIR6866 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR6866 Gene

  • MicroRNA 6866 2 3 5
  • MicroRNA Mir-6866 3
  • Hsa-Mir-6866 3
  • MIMAT0027633 51
  • MIMAT0027632 51
  • MI0022713 51
  • MIR6866 2

External Ids for MIR6866 Gene

Previous GeneCards Identifiers for MIR6866 Gene

  • GC17U902036

Summaries for MIR6866 Gene

Entrez Gene Summary for MIR6866 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6866 Gene

MIR6866 (MicroRNA 6866) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Gene Expression and Transport of Mature Transcript to Cytoplasm.

Additional gene information for MIR6866 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6866 Gene

Genomics for MIR6866 Gene

GeneHancer (GH) Regulatory Elements for MIR6866 Gene

Promoters and enhancers for MIR6866 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J040160 Enhancer 0.2 Ensembl 500.7 -1.8 -1832 0.2 MIR6866 MSL1 MED24 TOP2A CASC3
GH17J040138 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 -21.6 -21594 3.2 HNRNPK EP300 ZSCAN5C SIN3A NRF1 TCF12 ZNF300 POLR2G BCLAF1 RBAK CASC3 lnc-NR1D1-2 MED1 SMARCE1 CDK12 SNORD124 MED24 MSL1 RPL19 IGFBP4
GH17J040158 Enhancer 0.7 Ensembl 0.7 -3.5 -3532 2.4 ZNF623 ZNF316 MAFF MAFK ZBTB11 ZNF426 SPI1 MAFG ZFP64 NFE2 MED24 MSL1 MED1 SMARCE1 CDK12 TOP2A ENSG00000266208 MIR6866 CASC3
GH17J040151 Enhancer 1 Ensembl ENCODE 0.4 -9.3 -9333 3.2 ZBTB11 MEF2C RELA ZNF316 MAFF IRF1 MAFK ARNT ZNF592 NBN ENSG00000266208 MIR6866 CASC3
GH17J040146 Enhancer 0.3 Ensembl 0.4 -14.9 -14932 0.4 ATF2 CASC3 MIR6866
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6866 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6866 Gene

Genomic Locations for MIR6866 Gene
chr17:40,161,933-40,162,001
(GRCh38/hg38)
Size:
69 bases
Orientation:
Plus strand

Genomic View for MIR6866 Gene

Genes around MIR6866 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6866 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6866 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6866 Gene

Proteins for MIR6866 Gene

Post-translational modifications for MIR6866 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6866 Gene

Domains & Families for MIR6866 Gene

Gene Families for MIR6866 Gene

HGNC:
genes like me logo Genes that share domains with MIR6866: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6866 Gene

Function for MIR6866 Gene

Phenotypes From GWAS Catalog for MIR6866 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6866 Gene

Localization for MIR6866 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6866 Gene

Pathways & Interactions for MIR6866 Gene

genes like me logo Genes that share pathways with MIR6866: view
;

Gene Ontology (GO) - Biological Process for MIR6866 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR6866 Gene

Drugs & Compounds for MIR6866 Gene

No Compound Related Data Available

Transcripts for MIR6866 Gene

mRNA/cDNA for MIR6866 Gene

3 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
3 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6866 Gene

No ASD Table

Relevant External Links for MIR6866 Gene

GeneLoc Exon Structure for
MIR6866

Expression for MIR6866 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6866 Gene

Orthologs for MIR6866 Gene

Evolution for MIR6866 Gene

ENSEMBL:
Gene Tree for MIR6866 (if available)
TreeFam:
Gene Tree for MIR6866 (if available)

No data available for Orthologs for MIR6866 Gene

Paralogs for MIR6866 Gene

No data available for Paralogs for MIR6866 Gene

Variants for MIR6866 Gene

Additional dbSNP identifiers (rs#s) for MIR6866 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6866 Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv525796 CNV gain 19592680
nsv833444 CNV loss 17160897

Additional Variant Information for MIR6866 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6866

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6866 Gene

Disorders for MIR6866 Gene

Additional Disease Information for MIR6866

No disorders were found for MIR6866 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6866 Gene

Publications for MIR6866 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6866 Gene

Sources for MIR6866 Gene