microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6860 Gene

Subcategory (RNA class) for MIR6860 Gene

miRNA

Number of RNA Genes sources:

1 / 14

Aliases for MIR6860 Gene

  • MicroRNA 6860 2 3 5
  • MicroRNA Mir-6860 3
  • Hsa-Mir-6860 3
  • MIMAT0027622 51
  • MI0022707 51
  • MIR6860 2

External Ids for MIR6860 Gene

Previous GeneCards Identifiers for MIR6860 Gene

  • GC11U902130

Summaries for MIR6860 Gene

Entrez Gene Summary for MIR6860 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6860 Gene

MIR6860 (MicroRNA 6860) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6860 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6860 Gene

Genomics for MIR6860 Gene

GeneHancer (GH) Regulatory Elements for MIR6860 Gene

Promoters and enhancers for MIR6860 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J067045 Enhancer 0.8 ENCODE 500.7 -0.2 -208 0.2 JUND FOS ZNF10 ZIC2 RBM25 KDM1A CTCF TCF12 FOSL1 ZNF184 MIR6860 lnc-RHOD-3 SYT12
GH11J067046 Enhancer 0.7 Ensembl 500.7 +0.2 157 0.4 ZNF10 ZIC2 RBM25 KDM1A CTCF TCF12 ZNF184 FOSL2 RCOR1 SMARCA5 MIR6860 lnc-PC-1 SYT12
GH11J067044 Enhancer 0.5 Ensembl 500.7 -0.6 -642 0.4 CTCF EZH2 SMARCB1 ADNP VEZF1 MAZ ZBTB21 ATF1 MIR6860 NUDT8 lnc-RHOD-3 SYT12
GH11J067030 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -12.9 -12939 4.6 ZNF217 JUND FOS KLF4 RFX1 CUX1 CHD1 CTBP1 SREBF2 RBM25 RHOD PC LRFN4 SYT12 CTSF lnc-RHOD-3 MIR6860
GH11J067026 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -17.6 -17602 2.9 ZNF217 SP1 RFX1 MEF2C CUX1 EZH2 GATAD2B CTBP1 FOXA2 BCL11A lnc-RHOD-3 RHOD SYT12 RNU7-23P PC LRFN4 MIR6860
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6860 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6860 Gene

Genomic Locations for MIR6860 Gene
chr11:67,045,643-67,045,708
(GRCh38/hg38)
Size:
66 bases
Orientation:
Plus strand

Genomic View for MIR6860 Gene

Genes around MIR6860 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6860 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6860 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6860 Gene

Proteins for MIR6860 Gene

Post-translational modifications for MIR6860 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6860 Gene

Domains & Families for MIR6860 Gene

Gene Families for MIR6860 Gene

HGNC:
genes like me logo Genes that share domains with MIR6860: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6860 Gene

Function for MIR6860 Gene

Phenotypes From GWAS Catalog for MIR6860 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6860 Gene

Localization for MIR6860 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6860 Gene

Pathways & Interactions for MIR6860 Gene

PathCards logo

SuperPathways for MIR6860 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for MIR6860 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6860 Gene

Drugs & Compounds for MIR6860 Gene

No Compound Related Data Available

Transcripts for MIR6860 Gene

mRNA/cDNA for MIR6860 Gene

2 RNACentral transcripts :
1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
2 miRBase transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6860 Gene

No ASD Table

Relevant External Links for MIR6860 Gene

GeneLoc Exon Structure for
MIR6860

Expression for MIR6860 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6860 Gene

Orthologs for MIR6860 Gene

Evolution for MIR6860 Gene

ENSEMBL:
Gene Tree for MIR6860 (if available)
TreeFam:
Gene Tree for MIR6860 (if available)

No data available for Orthologs for MIR6860 Gene

Paralogs for MIR6860 Gene

No data available for Paralogs for MIR6860 Gene

Variants for MIR6860 Gene

Additional dbSNP identifiers (rs#s) for MIR6860 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6860 Gene

Variant ID Type Subtype PubMed ID
dgv1973n54 CNV loss 21841781
nsv555226 CNV gain 21841781

Additional Variant Information for MIR6860 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6860

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6860 Gene

Disorders for MIR6860 Gene

Additional Disease Information for MIR6860

No disorders were found for MIR6860 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6860 Gene

Publications for MIR6860 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 54
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 54

Products for MIR6860 Gene

Sources for MIR6860 Gene