microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6860 Gene

Data sources for MIR6860 Gene:

RNA type for MIR6860 Gene

miRNA

Aliases for MIR6860 Gene

External Ids for MIR6860 Gene

Previous GeneCards Identifiers for MIR6860 Gene

  • GC11U902130

Summaries for MIR6860 Gene

Entrez Gene Summary for MIR6860 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6860 Gene

MIR6860 (MicroRNA 6860) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6860 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6860 Gene

Genomics for MIR6860 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6860 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J067045 Enhancer 0.9 Ensembl ENCODE 250.7 -0.1 -69 0.9 JUND ZNF10 ZIC2 BHLHE40 RAD21 SMC3 CTCF SMARCA5 CBX1 ZNF189 MIR6860 RHOD HSALNG0085099 SYT12
GH11J067030 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -12.9 -12939 4.6 JUND CEBPB FEZF1 ZNF217 EP300 MBD2 CTBP1 CUX1 ZKSCAN1 RAD21 RHOD PC LRFN4 SYT12 CTSF HSALNG0085099 MIR6860
GH11J067048 Enhancer 0.3 Ensembl ENCODE 0.7 +3.3 3323 1.3 lnc-PC-1 NUDT8 MIR6860 RHOD SYT12
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6860 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6860 Gene

Latest Assembly
chr11:67,045,643-67,045,708
(GRCh38/hg38)
Size:
66 bases
Orientation:
Plus strand

Previous Assembly
chr11:66,813,114-66,813,179
(GRCh37/hg19 by Entrez Gene)
Size:
66 bases
Orientation:
Plus strand

Genomic View for MIR6860 Gene

Genes around MIR6860 on UCSC Golden Path with GeneCards custom track
MIR6860 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6860 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6860 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6860 Gene

Proteins for MIR6860 Gene

Post-translational modifications for MIR6860 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6860 Gene

Domains & Families for MIR6860 Gene

Gene Families for MIR6860 Gene

HGNC:
genes like me logo Genes that share domains with MIR6860: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6860 Gene

Function for MIR6860 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6860 Gene

Localization for MIR6860 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6860 Gene

Pathways & Interactions for MIR6860 Gene

PathCards logo

SuperPathways for MIR6860 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6860 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6860 Gene

Drugs & Compounds for MIR6860 Gene

No Compound Related Data Available

Transcripts for MIR6860 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6860 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075A7C9_9606 pre_miRNA 66 3

RefSeq: NR_106920,

Ensembl: ENST00000635882 (view in UCSC) ,

miRBase: MI0022707,

URS000075BCE7_9606 miRNA 22 2

RefSeq: NR_106920,

miRBase: MIMAT0027622,

MIR6860 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6860 Gene

No ASD Table

Relevant External Links for MIR6860 Gene

GeneLoc Exon Structure for
MIR6860

No data available for mRNA/cDNA for MIR6860 Gene

Expression for MIR6860 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6860 Gene

Orthologs for MIR6860 Gene

Evolution for MIR6860 Gene

ENSEMBL:
Gene Tree for MIR6860 (if available)
TreeFam:
Gene Tree for MIR6860 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR6860

No data available for Orthologs for MIR6860 Gene

Paralogs for MIR6860 Gene

No data available for Paralogs for MIR6860 Gene

Variants for MIR6860 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6860 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR6860 Gene

Variant ID Type Subtype PubMed ID
dgv1973n54 CNV loss 21841781
nsv555226 CNV gain 21841781

Additional Variant Information for MIR6860 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6860
Leiden Open Variation Database (LOVD)
MIR6860

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6860 Gene

Disorders for MIR6860 Gene

Additional Disease Information for MIR6860

No disorders were found for MIR6860 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6860 Gene

Publications for MIR6860 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6860 Gene

Sources for MIR6860 Gene