microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6855 Gene

Data sources for MIR6855 Gene:

RNA type for MIR6855 Gene

miRNA

Aliases for MIR6855 Gene

External Ids for MIR6855 Gene

Previous GeneCards Identifiers for MIR6855 Gene

  • GC09U902162

Summaries for MIR6855 Gene

Entrez Gene Summary for MIR6855 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6855 Gene

MIR6855 (MicroRNA 6855) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6855 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6855 Gene

Genomics for MIR6855 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6855 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J129860 Promoter/Enhancer 1.5 Ensembl ENCODE dbSUPER 0.7 -3.9 -3910 10.3 IKZF1 NCOR1 MYC SIX5 ZIC2 REST HES1 BHLHE40 TBP MNT EXOSC2 NUP188 FUBP3 C9orf78 USP20 ABL1 ASB6 TOR1A TOR1B MIR6855
GH09J129878 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 +9.5 9457 1.9 MYC ZIC2 BHLHE40 TBP NFE2 TAL1 STAT5A ETV1 POLR2A ZNF384 piR-38375 C9orf78 FNBP1 TOR1B MIR6855 USP20 GPR107
GH09J129876 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.4 +7.2 7232 1.3 EBF1 BHLHE40 ELF1 IKZF1 SPI1 ZBTB33 DPF2 ZNF121 TOR1A TOR1B piR-38375 MIR6855 C9orf78 USP20 GPR107
GH09J129851 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 -15.9 -15904 4.2 ZNF580 ZIC2 ZNF217 PTBP1 HLTF SMARCE1 POLR2A ZBTB33 ATF4 TEAD4 C9orf78 TOR1A TOR1B USP20 MIR6855 GPR107
GH09J129856 Enhancer 0.8 Ensembl dbSUPER 0.4 -12.3 -12263 0.6 MYC BHLHE40 MNT RELA IRF9 RAD51 TCF12 TEAD4 L3MBTL2 HDAC1 TOR1A MIR6855 C9orf78 USP20 GPR107
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6855 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6855 Gene

Latest Assembly
chr9:129,869,605-129,869,671
(GRCh38/hg38)
Size:
67 bases
Orientation:
Plus strand

Previous Assembly
chr9:132,631,884-132,631,950
(GRCh37/hg19 by Entrez Gene)
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR6855 Gene

Genes around MIR6855 on UCSC Golden Path with GeneCards custom track
MIR6855 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6855 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6855 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6855 Gene

Proteins for MIR6855 Gene

Post-translational modifications for MIR6855 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6855 Gene

Domains & Families for MIR6855 Gene

Gene Families for MIR6855 Gene

HGNC:
genes like me logo Genes that share domains with MIR6855: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6855 Gene

Function for MIR6855 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6855 Gene

Localization for MIR6855 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6855 Gene

Pathways & Interactions for MIR6855 Gene

PathCards logo

SuperPathways for MIR6855 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6855 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6855 Gene

Drugs & Compounds for MIR6855 Gene

No Compound Related Data Available

Transcripts for MIR6855 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6855 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS0000759BC7_9606 pre_miRNA 67 3

RefSeq: NR_106914,

Ensembl: ENST00000622178 (view in UCSC) ,

miRBase: MI0022701,

URS000075AFD3_9606 miRNA 25 2

RefSeq: NR_106914,

miRBase: MIMAT0027610,

URS000075C1AC_9606 miRNA 22 2

RefSeq: NR_106914,

miRBase: MIMAT0027611,

MIR6855 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6855 Gene

No ASD Table

Relevant External Links for MIR6855 Gene

GeneLoc Exon Structure for
MIR6855

No data available for mRNA/cDNA for MIR6855 Gene

Expression for MIR6855 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6855 Gene

Orthologs for MIR6855 Gene

Evolution for MIR6855 Gene

ENSEMBL:
Gene Tree for MIR6855 (if available)
TreeFam:
Gene Tree for MIR6855 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR6855

No data available for Orthologs for MIR6855 Gene

Paralogs for MIR6855 Gene

No data available for Paralogs for MIR6855 Gene

Variants for MIR6855 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6855 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR6855 Gene

Variant ID Type Subtype PubMed ID
dgv1511e214 CNV gain 21293372
esv3621839 CNV loss 21293372
nsv1046477 CNV gain 25217958
nsv1161909 CNV duplication 26073780
nsv469902 CNV loss 18288195
nsv517374 CNV loss 19592680
nsv8571 CNV gain 18304495

Additional Variant Information for MIR6855 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6855
Leiden Open Variation Database (LOVD)
MIR6855

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6855 Gene

Disorders for MIR6855 Gene

Additional Disease Information for MIR6855

No disorders were found for MIR6855 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6855 Gene

Publications for MIR6855 Gene

  1. The role of the redox/miR-6855-3p/PRDX5A axis in reversing SLUG-mediated BRCA2 silencing in breast cancer cells. (PMID: 31987042) Ellison M … Misra S (Cell communication and signaling : CCS 2020) 3
  2. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6855 Gene

Sources for MIR6855 Gene