microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6852 Gene

Subcategory (RNA class) for MIR6852 Gene

miRNA

Number of RNA Genes sources:

2 / 17

Aliases for MIR6852 Gene

  • MicroRNA 6852 2 3 5
  • Hsa-Mir-6852 2 3
  • MIR6852 2 5
  • MicroRNA Mir-6852 3
  • MIMAT0027605 50
  • MIMAT0027604 50
  • MI0022698 50

External Ids for MIR6852 Gene

Previous GeneCards Identifiers for MIR6852 Gene

  • GC09U902102

Summaries for MIR6852 Gene

Entrez Gene Summary for MIR6852 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6852 Gene

MIR6852 (MicroRNA 6852) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are RET signaling and Paradoxical activation of RAF signaling by kinase inactive BRAF.

Additional gene information for MIR6852 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6852 Gene

Genomics for MIR6852 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6852 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J035710 Enhancer 0.5 dbSUPER 600.7 -0.7 -663 1.9 DDX20 ESR1 CTBP1 PKNOX1 NFIB ZNF687 MIR6852 piR-43105-659 TPM2 FJ601678-147 TLN1 RF00017-7533
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6852 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6852 Gene

Genomic Locations for MIR6852 Gene
chr9:35,710,676-35,710,741
(GRCh38/hg38)
Size:
66 bases
Orientation:
Minus strand

Genomic View for MIR6852 Gene

Genes around MIR6852 on UCSC Golden Path with GeneCards custom track
MIR6852 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6852 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6852 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6852 Gene

Proteins for MIR6852 Gene

Post-translational modifications for MIR6852 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6852 Gene

Domains & Families for MIR6852 Gene

Gene Families for MIR6852 Gene

HGNC:
genes like me logo Genes that share domains with MIR6852: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6852 Gene

Function for MIR6852 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6852 Gene

Localization for MIR6852 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6852 Gene

Pathways & Interactions for MIR6852 Gene

PathCards logo

SuperPathways for MIR6852 Gene

SuperPathway Contained pathways
1 RET signaling
2 Paradoxical activation of RAF signaling by kinase inactive BRAF
3 Integrin alphaIIb beta3 signaling
4 Response to elevated platelet cytosolic Ca2+
5 Unfolded Protein Response (UPR)
genes like me logo Genes that share pathways with MIR6852: view

Gene Ontology (GO) - Biological Process for MIR6852 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR6852 Gene

Drugs & Compounds for MIR6852 Gene

No Compound Related Data Available

Transcripts for MIR6852 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6852 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D075_9606 precursor_RNA 66 4

HGNC: 49993,

RefSeq: NR_106911,

Ensembl: ENST00000621699 (view in UCSC) ,

miRBase: MI0022698,

URS000075E060_9606 miRNA 21 2

RefSeq: NR_106911,

miRBase: MIMAT0027604,

URS000075E354_9606 miRNA 17 2

RefSeq: NR_106911,

miRBase: MIMAT0027605,

URS0000163B6F_9606 miRNA 22 1

ENA: KC832803.1:50..71:ncRNA,

MIR6852 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6852 Gene

No ASD Table

Relevant External Links for MIR6852 Gene

GeneLoc Exon Structure for
MIR6852

No data available for mRNA/cDNA for MIR6852 Gene

Expression for MIR6852 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6852 Gene

Orthologs for MIR6852 Gene

Evolution for MIR6852 Gene

ENSEMBL:
Gene Tree for MIR6852 (if available)
TreeFam:
Gene Tree for MIR6852 (if available)

No data available for Orthologs for MIR6852 Gene

Paralogs for MIR6852 Gene

No data available for Paralogs for MIR6852 Gene

Variants for MIR6852 Gene

Additional dbSNP identifiers (rs#s) for MIR6852 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6852 Gene

Variant ID Type Subtype PubMed ID
nsv1125318 OTHER inversion 24896259

Additional Variant Information for MIR6852 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6852

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6852 Gene

Disorders for MIR6852 Gene

Additional Disease Information for MIR6852

No disorders were found for MIR6852 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6852 Gene

Publications for MIR6852 Gene

  1. Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties. (PMID: 23535375) Swaminathan S … Imamichi T (Biochemical and biophysical research communications 2013) 3
  2. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6852 Gene

Sources for MIR6852 Gene