microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6849 Gene

Data sources for MIR6849 Gene:

RNA type for MIR6849 Gene

miRNA

Aliases for MIR6849 Gene

External Ids for MIR6849 Gene

Previous GeneCards Identifiers for MIR6849 Gene

  • GC08U901854

Summaries for MIR6849 Gene

Entrez Gene Summary for MIR6849 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6849 Gene

MIR6849 (MicroRNA 6849) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Processing of Capped Intronless Pre-mRNA and Tat-mediated elongation of the HIV-1 transcript.

Additional gene information for MIR6849 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6849 Gene

Genomics for MIR6849 Gene

Genomic Locations for MIR6849 Gene

Latest Assembly
chr8:144,400,277-144,400,345
(GRCh38/hg38)
Size:
69 bases
Orientation:
Minus strand

Previous Assembly
chr8:145,625,671-145,625,739
(GRCh37/hg19 by Entrez Gene)
Size:
69 bases
Orientation:
Minus strand

Alternative Locations (GRCh38/hg38)

  • chr8(PATCHES):130,880-130,948 (-)

Genomic View for MIR6849 Gene

Genes around MIR6849 on UCSC Golden Path with GeneCards custom track
MIR6849 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR6849 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6849 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6849 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR6849 Gene

Proteins for MIR6849 Gene

Post-translational modifications for MIR6849 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6849 Gene

Domains & Families for MIR6849 Gene

Gene Families for MIR6849 Gene

HGNC:
genes like me logo Genes that share domains with MIR6849: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6849 Gene

Function for MIR6849 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6849 Gene

Localization for MIR6849 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6849 Gene

Pathways & Interactions for MIR6849 Gene

genes like me logo Genes that share pathways with MIR6849: view

Pathways by source for MIR6849 Gene

Gene Ontology (GO) - Biological Process for MIR6849 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR6849 Gene

Drugs & Compounds for MIR6849 Gene

No Compound Related Data Available

Transcripts for MIR6849 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6849 Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000075E2F8_9606 precursor_RNA 69 3

RefSeq: NR_106908,

Ensembl: ENST00000618543 (view in UCSC) ,

miRBase: MI0022695,

URS000075D40D_9606 miRNA 23 2

RefSeq: NR_106908,

miRBase: MIMAT0027598,

URS000075C7D0_9606 miRNA 22 2

RefSeq: NR_106908,

miRBase: MIMAT0027599,

MIR6849 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6849 Gene

No ASD Table

Relevant External Links for MIR6849 Gene

GeneLoc Exon Structure for
MIR6849

No data available for mRNA/cDNA for MIR6849 Gene

Expression for MIR6849 Gene

No Expression Related Data Available

Primer products for research

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6849 Gene

Orthologs for MIR6849 Gene

Evolution for MIR6849 Gene

ENSEMBL:
Gene Tree for MIR6849 (if available)
TreeFam:
Gene Tree for MIR6849 (if available)
Alliance of Genome Resources:
Additional Orthologs for MIR6849

No data available for Orthologs for MIR6849 Gene

Paralogs for MIR6849 Gene

No data available for Paralogs for MIR6849 Gene

Variants for MIR6849 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR6849 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR6849 Gene

Variant ID Type Subtype PubMed ID
dgv12434n54 CNV loss 21841781
dgv12437n54 CNV loss 21841781
esv2759652 CNV gain+loss 17122850
nsv428208 CNV gain 18775914
nsv470249 CNV loss 18288195
nsv515809 CNV gain+loss 19592680
nsv824805 CNV gain 20364138
nsv831489 CNV loss 17160897

Additional Variant Information for MIR6849 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6849
Leiden Open Variation Database (LOVD)
MIR6849

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6849 Gene

Disorders for MIR6849 Gene

Additional Disease Information for MIR6849

No disorders were found for MIR6849 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6849 Gene

Publications for MIR6849 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6849 Gene

Sources for MIR6849 Gene