microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6847 Gene

Subcategory (RNA class) for MIR6847 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6847 Gene

  • MicroRNA 6847 2 3 5
  • Hsa-Mir-6847 2 3
  • MIR6847 2 5
  • MicroRNA Mir-6847 3
  • MIMAT0027595 50
  • MIMAT0027594 50
  • MI0022693 50

External Ids for MIR6847 Gene

Previous GeneCards Identifiers for MIR6847 Gene

  • GC08U901941

Summaries for MIR6847 Gene

Entrez Gene Summary for MIR6847 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6847 Gene

MIR6847 (MicroRNA 6847) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are rRNA processing in the nucleus and cytosol and Regulation of activated PAK-2p34 by proteasome mediated degradation.

Additional gene information for MIR6847 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6847 Gene

Genomics for MIR6847 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6847 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J144077 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 -1.1 -1145 3.5 ARHGAP35 SP1 HNRNPL CREB1 GATAD2A PRDM10 ZNF629 TFE3 SIX5 LEF1 MIR6847 EXOSC4 WDR97 MAF1 ENSG00000255224 ZNF623 ZNF16 TMED10P1 ZNF7 ENSG00000255164
GH08J144073 Promoter/Enhancer 1.5 FANTOM5 Ensembl ENCODE 0.4 -5.5 -5484 1.2 ZBTB33 LEF1 IKZF1 JUND MTA2 PKNOX1 ZNF24 BRD9 DPF2 HDAC1 ZNF251 WDR97 ZNF696 ZNF252P ENSG00000254533 TSSK5P SPATC1 ENSG00000255085 CYC1 MAF1
GH08J144069 Enhancer 0.9 ENCODE dbSUPER 0.4 -9.8 -9780 0.4 GATAD2A RXRB CEBPA SOX13 ZBTB25 CREM SAP130 MIER3 ZGPAT FOSL2 ENSG00000255224 PARP10 SPATC1 MIR6847 EXOSC4 GPAA1
GH08J144068 Enhancer 0.6 Ensembl dbSUPER 0.4 -11.4 -11373 0.6 L3MBTL2 ARID1B SMARCA4 PARP10 SPATC1 CYC1 SHARPIN WDR97 MAF1 EXOSC4 GPAA1 MIR6847
GH08J144067 Enhancer 0.3 Ensembl 0.4 -12.0 -11973 0.2 USF2 ZFP36 PARP10 SPATC1 CYC1 WDR97 MAF1 SHARPIN EXOSC4 GPAA1 MIR6847
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6847 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6847 Gene

Genomic Locations for MIR6847 Gene
chr8:144,079,874-144,079,942
(GRCh38/hg38)
Size:
69 bases
Orientation:
Plus strand

Genomic View for MIR6847 Gene

Genes around MIR6847 on UCSC Golden Path with GeneCards custom track
MIR6847 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6847 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6847 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6847 Gene

Proteins for MIR6847 Gene

Post-translational modifications for MIR6847 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6847 Gene

Domains & Families for MIR6847 Gene

Gene Families for MIR6847 Gene

HGNC:
genes like me logo Genes that share domains with MIR6847: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6847 Gene

Function for MIR6847 Gene

Phenotypes From GWAS Catalog for MIR6847 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6847 Gene

Localization for MIR6847 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6847 Gene

Pathways & Interactions for MIR6847 Gene

genes like me logo Genes that share pathways with MIR6847: view

Gene Ontology (GO) - Biological Process for MIR6847 Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MIR6847 Gene

Drugs & Compounds for MIR6847 Gene

No Compound Related Data Available

Transcripts for MIR6847 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6847 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075D9A8_9606 precursor_RNA 69 4

HGNC: 50022,

RefSeq: NR_106906,

Ensembl: ENST00000618235 (view in UCSC) ,

miRBase: MI0022693,

URS000075DD4B_9606 miRNA 23 2

RefSeq: NR_106906,

miRBase: MIMAT0027594,

URS000075EBAD_9606 miRNA 22 2

RefSeq: NR_106906,

miRBase: MIMAT0027595,

MIR6847 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6847 Gene

No ASD Table

Relevant External Links for MIR6847 Gene

GeneLoc Exon Structure for
MIR6847

No data available for mRNA/cDNA for MIR6847 Gene

Expression for MIR6847 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6847 Gene

Orthologs for MIR6847 Gene

Evolution for MIR6847 Gene

ENSEMBL:
Gene Tree for MIR6847 (if available)
TreeFam:
Gene Tree for MIR6847 (if available)

No data available for Orthologs for MIR6847 Gene

Paralogs for MIR6847 Gene

No data available for Paralogs for MIR6847 Gene

Variants for MIR6847 Gene

Additional dbSNP identifiers (rs#s) for MIR6847 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6847 Gene

Variant ID Type Subtype PubMed ID
dgv12431n54 CNV loss 21841781
dgv12433n54 CNV gain 21841781
dgv906n27 CNV loss 19166990
esv2759651 CNV gain 17122850
esv29971 CNV loss 17803354
nsv1025071 CNV gain 25217958
nsv1161815 CNV deletion 26073780
nsv428208 CNV gain 18775914
nsv466014 CNV loss 19166990
nsv470249 CNV loss 18288195
nsv470250 CNV gain 18288195
nsv515809 CNV gain+loss 19592680
nsv612906 CNV loss 21841781
nsv612907 CNV gain+loss 21841781
nsv612914 CNV loss 21841781
nsv612915 CNV loss 21841781
nsv6447 CNV insertion 18451855
nsv950015 CNV deletion 24416366

Additional Variant Information for MIR6847 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6847

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6847 Gene

Disorders for MIR6847 Gene

No disorders were found for MIR6847 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6847 Gene

Publications for MIR6847 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6847 Gene

Sources for MIR6847 Gene