microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6841 Gene

Subcategory (RNA class) for MIR6841 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6841 Gene

  • MicroRNA 6841 2 3 5
  • Hsa-Mir-6841 2 3
  • MIR6841 2 5
  • MicroRNA Mir-6841 3
  • MIMAT0027585 50
  • MIMAT0027584 50
  • MI0022687 50

External Ids for MIR6841 Gene

Previous GeneCards Identifiers for MIR6841 Gene

  • GC08U901858

Summaries for MIR6841 Gene

Entrez Gene Summary for MIR6841 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6841 Gene

MIR6841 (MicroRNA 6841) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6841 include Charcot-Marie-Tooth Disease.

Additional gene information for MIR6841 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6841 Gene

Genomics for MIR6841 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6841 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J024952 Enhancer 0.3 Ensembl 600.7 +1.0 966 0.2 ZNF189 MIR6841 piR-54209 piR-60048 NEFM ENSG00000253535 NEFL lnc-NEFL-2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6841 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6841 Gene

Genomic Locations for MIR6841 Gene
chr8:24,953,796-24,953,867
(GRCh38/hg38)
Size:
72 bases
Orientation:
Minus strand

Genomic View for MIR6841 Gene

Genes around MIR6841 on UCSC Golden Path with GeneCards custom track
MIR6841 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6841 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6841 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6841 Gene

Proteins for MIR6841 Gene

Post-translational modifications for MIR6841 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6841 Gene

Domains & Families for MIR6841 Gene

Gene Families for MIR6841 Gene

HGNC:
genes like me logo Genes that share domains with MIR6841: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6841 Gene

Function for MIR6841 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6841 Gene

Localization for MIR6841 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6841 Gene

Pathways & Interactions for MIR6841 Gene

PathCards logo

SuperPathways for MIR6841 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6841 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6841 Gene

Drugs & Compounds for MIR6841 Gene

No Compound Related Data Available

Transcripts for MIR6841 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6841 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075B664_9606 precursor_RNA 72 4

HGNC: 50070,

RefSeq: NR_106900,

Ensembl: ENST00000637129 (view in UCSC) ,

miRBase: MI0022687,

URS000075C704_9606 miRNA 22 2

RefSeq: NR_106900,

miRBase: MIMAT0027584,

URS000075CB32_9606 miRNA 21 2

RefSeq: NR_106900,

miRBase: MIMAT0027585,

MIR6841 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6841 Gene

No ASD Table

Relevant External Links for MIR6841 Gene

GeneLoc Exon Structure for
MIR6841

No data available for mRNA/cDNA for MIR6841 Gene

Expression for MIR6841 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6841 Gene

Orthologs for MIR6841 Gene

Evolution for MIR6841 Gene

ENSEMBL:
Gene Tree for MIR6841 (if available)
TreeFam:
Gene Tree for MIR6841 (if available)

No data available for Orthologs for MIR6841 Gene

Paralogs for MIR6841 Gene

No data available for Paralogs for MIR6841 Gene

Variants for MIR6841 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR6841 Gene

SNP ID Clinical significance and condition Chr 08 pos Variation AA Info Type
916904 Likely Benign: Charcot-Marie-Tooth disease 24,953,814(-) G/A NON_CODING_TRANSCRIPT_VARIANT,INTRON_VARIANT
rs76347846 Benign/Likely Benign: Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease, type I; not specified 24,953,808(-) A/G NON_CODING_TRANSCRIPT_VARIANT

Additional dbSNP identifiers (rs#s) for MIR6841 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6841 Gene

Variant ID Type Subtype PubMed ID
esv3616666 OTHER inversion 21293372
esv3891377 CNV loss 25118596

Additional Variant Information for MIR6841 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6841

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6841 Gene

Disorders for MIR6841 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6841 Gene - From: GeneCards

Disorder Aliases PubMed IDs
charcot-marie-tooth disease
  • peroneal muscular atrophy
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6841

genes like me logo Genes that share disorders with MIR6841: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6841 Gene

Publications for MIR6841 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6841 Gene

Sources for MIR6841 Gene