microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6819 Gene

Subcategory (RNA class) for MIR6819 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6819 Gene

  • MicroRNA 6819 2 3 5
  • Hsa-Mir-6819 2 3
  • MIR6819 2 5
  • MicroRNA Mir-6819 3
  • MIMAT0027538 50
  • MIMAT0027539 50
  • MI0022664 50

External Ids for MIR6819 Gene

Previous GeneCards Identifiers for MIR6819 Gene

  • GC22U900975

Summaries for MIR6819 Gene

Entrez Gene Summary for MIR6819 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6819 Gene

MIR6819 (MicroRNA 6819) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6819 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6819 Gene

Genomics for MIR6819 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6819 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22J036284 Enhancer 1.1 Ensembl ENCODE dbSUPER 600.7 +0.8 797 2.7 CTCF ZNF143 ZIC2 REST RAD21 POLR2A TRIM22 DPF2 KLF9 KLF7 MIR6819 EIF3D MCM5 RPS15AP38 HSALNG0135214 APOL1 MYH9
GH22J036287 Enhancer 0.8 Ensembl ENCODE dbSUPER 0.7 -2.5 -2480 3.2 RBM22 KLF8 ZBTB6 POLR2A piR-55654-327 piR-45504-352 piR-55655-370 piR-56022-363 piR-49732-385 piR-48301-268 piR-60597-050 piR-61028-382 MIR6819 APOL1
GH22J036281 Enhancer 0.3 dbSUPER 0.7 +4.6 4564 1.7 RBM22 EGR2 HSALNG0135214 ENSG00000252225 APOL3 MIR6819 APOL1 MYH9
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6819 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6819 Gene

Genomic Locations for MIR6819 Gene
chr22:36,286,847-36,286,907
(GRCh38/hg38)
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR6819 Gene

Genes around MIR6819 on UCSC Golden Path with GeneCards custom track
MIR6819 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6819 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6819 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6819 Gene

Proteins for MIR6819 Gene

Post-translational modifications for MIR6819 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6819 Gene

Domains & Families for MIR6819 Gene

Gene Families for MIR6819 Gene

HGNC:
genes like me logo Genes that share domains with MIR6819: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6819 Gene

Function for MIR6819 Gene

Phenotypes From GWAS Catalog for MIR6819 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6819 Gene

Localization for MIR6819 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6819 Gene

Pathways & Interactions for MIR6819 Gene

PathCards logo

SuperPathways for MIR6819 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6819 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6819 Gene

Drugs & Compounds for MIR6819 Gene

No Compound Related Data Available

Transcripts for MIR6819 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6819 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075C497_9606 precursor_RNA 61 4

HGNC: 50155,

RefSeq: NR_106877,

Ensembl: ENST00000622122 (view in UCSC) ,

miRBase: MI0022664,

URS000075DD69_9606 miRNA 22 2

RefSeq: NR_106877,

miRBase: MIMAT0027538,

URS000075B71F_9606 miRNA 21 2

RefSeq: NR_106877,

miRBase: MIMAT0027539,

MIR6819 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6819 Gene

No ASD Table

Relevant External Links for MIR6819 Gene

GeneLoc Exon Structure for
MIR6819

No data available for mRNA/cDNA for MIR6819 Gene

Expression for MIR6819 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6819 Gene

Orthologs for MIR6819 Gene

Evolution for MIR6819 Gene

ENSEMBL:
Gene Tree for MIR6819 (if available)
TreeFam:
Gene Tree for MIR6819 (if available)

No data available for Orthologs for MIR6819 Gene

Paralogs for MIR6819 Gene

No data available for Paralogs for MIR6819 Gene

Variants for MIR6819 Gene

Additional dbSNP identifiers (rs#s) for MIR6819 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6819 Gene

Variant ID Type Subtype PubMed ID
dgv4564n100 CNV gain 25217958
esv2760715 CNV gain 21179565
esv3568385 CNV loss 25503493
esv3647682 CNV gain 21293372
nsv522931 CNV gain 19592680
nsv523629 CNV loss 19592680
nsv523911 CNV loss 19592680
nsv834185 CNV loss 17160897

Additional Variant Information for MIR6819 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6819

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6819 Gene

Disorders for MIR6819 Gene

Additional Disease Information for MIR6819

No disorders were found for MIR6819 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6819 Gene

Publications for MIR6819 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6819 Gene

Sources for MIR6819 Gene