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Aliases for MIR6819 Gene

Subcategory (RNA class) for MIR6819 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR6819 Gene

  • MicroRNA 6819 2 3 5
  • MicroRNA Mir-6819 3
  • Hsa-Mir-6819 3

External Ids for MIR6819 Gene

Previous GeneCards Identifiers for MIR6819 Gene

  • GC22U900975

Summaries for MIR6819 Gene

Entrez Gene Summary for MIR6819 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6819 Gene

MIR6819 (MicroRNA 6819) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6819 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6819 Gene

Genomics for MIR6819 Gene

GeneHancer (GH) Regulatory Elements for MIR6819 Gene

Promoters and enhancers for MIR6819 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I036284 Enhancer 1 ENCODE dbSUPER 550.8 +0.8 797 2.7 HDGF RB1 ARID4B KLF17 ZNF2 RAD21 ZNF143 KLF7 ZNF654 RXRA MIR6819 APOL1 MYH9
GH22I036287 Enhancer 0.5 ENCODE dbSUPER 550.8 -1.2 -1176 0.6 KLF8 MIR6819 GC22M036301 MYH9
GH22I036252 Promoter/Enhancer 2 EPDnew Ensembl ENCODE dbSUPER 0.3 +32.8 32816 3.2 HDGF HDAC1 ELF3 TAF9B ARID4B ZBTB40 ETS1 EGR1 EGR2 NCOA1 APOL1 MYH9 CSF2RB MIR6819
GH22I036277 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.4 +9.1 9072 1.1 ELF3 CTCF RAD21 GLIS2 POLR2A PATZ1 VEZF1 SCRT2 ZNF143 SMC3 TXN2 APOL3 ENSG00000252225 MIR6819 APOL1
GH22I036297 Enhancer 1 ENCODE dbSUPER 0.4 -15.2 -15164 8.4 HDGF FOXA2 ARID4B SIN3A ZNF2 ZNF48 RAD21 ZNF366 SCRT2 ZNF143 TXN2 ENSG00000252225 APOL3 GC22M036301 MIR6819 MYH9
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR6819 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6819 Gene

Genomic Locations for MIR6819 Gene
chr22:36,286,847-36,286,907
(GRCh38/hg38)
Size:
61 bases
Orientation:
Minus strand

Genomic View for MIR6819 Gene

Genes around MIR6819 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6819 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6819 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6819 Gene

ORGUL Member Location for MIR6819 Gene

ORGUL Member Location for MIR6819 gene

Proteins for MIR6819 Gene

Post-translational modifications for MIR6819 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6819 Gene

Domains & Families for MIR6819 Gene

Gene Families for MIR6819 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6819: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6819 Gene

Function for MIR6819 Gene

Phenotypes From GWAS Catalog for MIR6819 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6819 Gene

Localization for MIR6819 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6819 Gene

Pathways & Interactions for MIR6819 Gene

SuperPathways for MIR6819 Gene

No Data Available

Interacting Proteins for MIR6819 Gene

Gene Ontology (GO) - Biological Process for MIR6819 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6819 Gene

Drugs & Compounds for MIR6819 Gene

No Compound Related Data Available

Transcripts for MIR6819 Gene

mRNA/cDNA for MIR6819 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6819 Gene

No ASD Table

Relevant External Links for MIR6819 Gene

GeneLoc Exon Structure for
MIR6819
ECgene alternative splicing isoforms for
MIR6819

Expression for MIR6819 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6819 Gene:

MIR6819
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6819 Gene

Orthologs for MIR6819 Gene

Evolution for MIR6819 Gene

ENSEMBL:
Gene Tree for MIR6819 (if available)
TreeFam:
Gene Tree for MIR6819 (if available)

No data available for Orthologs for MIR6819 Gene

Paralogs for MIR6819 Gene

No data available for Paralogs for MIR6819 Gene

Variants for MIR6819 Gene

Sequence variations from dbSNP and Humsavar for MIR6819 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs138158369 uncertain-significance, not specified, not provided 36,286,753(-) T/C downstream_transcript_variant
rs142094977 uncertain-significance, likely-benign, not specified, MYH9-related disorder, Nonsyndromic Hearing Loss, Dominant, not provided 36,286,827(-) A/G downstream_transcript_variant
rs143269195 benign, likely-benign, not specified, MYH9-related disorder, Nonsyndromic Hearing Loss, Dominant 36,288,770(-) C/T upstream_transcript_variant
rs143947828 conflicting-interpretations-of-pathogenicity, likely-benign, not specified, Nonsyndromic Hearing Loss, Dominant, MYH9-related disorder 36,288,306(-) G/A/T upstream_transcript_variant
rs143972348 uncertain-significance, MYH9-related disorder, Nonsyndromic Hearing Loss, Dominant 36,286,807(-) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6819 Gene

Variant ID Type Subtype PubMed ID
dgv4564n100 CNV gain 25217958
esv2760715 CNV gain 21179565
esv3568385 CNV loss 25503493
esv3647682 CNV gain 21293372
nsv522931 CNV gain 19592680
nsv523629 CNV loss 19592680
nsv523911 CNV loss 19592680
nsv834185 CNV loss 17160897

Additional Variant Information for MIR6819 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6819

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6819 Gene

Disorders for MIR6819 Gene

Additional Disease Information for MIR6819

No disorders were found for MIR6819 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6819 Gene

Publications for MIR6819 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6819 Gene

Sources for MIR6819 Gene

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