microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6814 Gene

Subcategory (RNA class) for MIR6814 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6814 Gene

  • MicroRNA 6814 2 3 5
  • Hsa-Mir-6814 2 3
  • MIR6814 2 5
  • MicroRNA Mir-6814 3
  • MIMAT0027529 50
  • MIMAT0027528 50
  • MI0022659 50

External Ids for MIR6814 Gene

Previous GeneCards Identifiers for MIR6814 Gene

  • GC21U900599

Summaries for MIR6814 Gene

Entrez Gene Summary for MIR6814 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6814 Gene

MIR6814 (MicroRNA 6814) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR6814 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6814 Gene

Genomics for MIR6814 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6814 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J041760 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.4 -19.1 -19102 10.8 CREB1 GATAD2A CTCF PRDM10 ZNF629 REST TFE3 SOX13 NFKBIZ ZNF692 RIPK4 LOC102724800 LINC00479 PRDM15 ENSG00000236883 LINC00112 MX2 ZBTB21 MX1 ABCG1
GH21J041756 Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -6.3 -6336 6.8 GATAD2A ZNF629 TFE3 NFKBIZ RCOR2 ZIC2 PKNOX1 RXRB PATZ1 SP1 LINC00479 LINC00112 PRDM15 MIR6814 RIPK4 TMPRSS2
GH21J041758 Enhancer 0.6 dbSUPER 0.4 -12.6 -12599 1.6 PRDM1 ZIC2 SP1 ZNF600 ZNF140 JUND NR2F2 TCF7L2 RAD21 HNF4A LINC00479 PRDM15 LINC00112 ENSG00000227698 RIPK4 MIR6814 TMPRSS2
GH21J041742 Enhancer 0.3 dbSUPER 0.7 +3.2 3198 1.8 POLR2A KLF1 LINC00479 LINC00112 ENSG00000236883 MIR6814 RIPK4 TMPRSS2
GH21J041757 Enhancer 0.3 Ensembl dbSUPER 0.4 -11.1 -11060 0.2 LINC00112 LINC00479 RIPK4 MIR6814 TMPRSS2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6814 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6814 Gene

Genomic Locations for MIR6814 Gene
chr21:41,746,772-41,746,841
(GRCh38/hg38)
Size:
70 bases
Orientation:
Minus strand

Genomic View for MIR6814 Gene

Genes around MIR6814 on UCSC Golden Path with GeneCards custom track
MIR6814 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6814 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6814 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6814 Gene

Proteins for MIR6814 Gene

Post-translational modifications for MIR6814 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6814 Gene

Domains & Families for MIR6814 Gene

Gene Families for MIR6814 Gene

HGNC:
genes like me logo Genes that share domains with MIR6814: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6814 Gene

Function for MIR6814 Gene

Phenotypes From GWAS Catalog for MIR6814 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6814 Gene

Localization for MIR6814 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6814 Gene

Pathways & Interactions for MIR6814 Gene

PathCards logo

SuperPathways for MIR6814 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6814 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6814 Gene

Drugs & Compounds for MIR6814 Gene

No Compound Related Data Available

Transcripts for MIR6814 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6814 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075A7D1_9606 precursor_RNA 70 4

HGNC: 50145,

RefSeq: NR_106872,

Ensembl: ENST00000622292 (view in UCSC) ,

miRBase: MI0022659,

URS000075CD8B_9606 miRNA 22 2

RefSeq: NR_106872,

miRBase: MIMAT0027529,

URS000075E7CD_9606 miRNA 22 2

RefSeq: NR_106872,

miRBase: MIMAT0027528,

MIR6814 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6814 Gene

No ASD Table

Relevant External Links for MIR6814 Gene

GeneLoc Exon Structure for
MIR6814

No data available for mRNA/cDNA for MIR6814 Gene

Expression for MIR6814 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6814 Gene

Orthologs for MIR6814 Gene

Evolution for MIR6814 Gene

ENSEMBL:
Gene Tree for MIR6814 (if available)
TreeFam:
Gene Tree for MIR6814 (if available)

No data available for Orthologs for MIR6814 Gene

Paralogs for MIR6814 Gene

No data available for Paralogs for MIR6814 Gene

Variants for MIR6814 Gene

Additional dbSNP identifiers (rs#s) for MIR6814 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6814 Gene

Variant ID Type Subtype PubMed ID
esv3893416 CNV gain 25118596
nsv1065094 CNV loss 25217958
nsv459265 CNV loss 19166990
nsv587562 CNV loss 21841781

Additional Variant Information for MIR6814 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6814

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR6814 Gene

Disorders for MIR6814 Gene

Additional Disease Information for MIR6814

No disorders were found for MIR6814 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR6814 Gene

Publications for MIR6814 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6814 Gene

Sources for MIR6814 Gene