microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR6793 Gene

Subcategory (RNA class) for MIR6793 Gene

miRNA

Number of RNA Genes sources:

1 / 17

Aliases for MIR6793 Gene

  • MicroRNA 6793 2 3 5
  • Hsa-Mir-6793 2 3
  • MIR6793 2 5
  • MicroRNA Mir-6793 3
  • MIMAT0027486 50
  • MIMAT0027487 50
  • MI0022638 50

External Ids for MIR6793 Gene

Previous GeneCards Identifiers for MIR6793 Gene

  • GC19U901786

Summaries for MIR6793 Gene

Entrez Gene Summary for MIR6793 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6793 Gene

MIR6793 (MicroRNA 6793) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6793 include Charcot-Marie-Tooth Disease, Dominant Intermediate B and Charcot-Marie-Tooth Disease.

Additional gene information for MIR6793 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MIR6793 Gene

Genomics for MIR6793 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR6793 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J010830 Enhancer 0.6 ENCODE 600.7 +0.2 247 0.2 CTCF ZBTB33 ZIC2 ZNF600 SCRT2 CREM HIC1 ATF3 MLLT1 ATF1 MIR6793 ILF3 TMED1 DNM2 lnc-TIMM29-1
GH19J010829 Enhancer 0.5 ENCODE 600.7 +0.4 424 0 ZIC2 CTCF SCRT2 HIC1 ZBTB33 RAD21 ATF1 MIR6793 ILF3 TMED1 DNM2 lnc-TIMM29-1
GH19J010834 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 +7.1 7136 2.6 RNF2 SP1 HNRNPL CREB1 TEAD4 PRDM10 REST ZNF629 TFE3 ZNF512 C19orf38 TMED1 KRI1 DNMT1 ILF3 ZNF491 ZNF627 ZNF441 RAVER1 ILF3-DT
GH19J010820 Enhancer 0.7 ENCODE 0.4 -7.9 -7870 0.7 REST HDAC1 SOX6 TCF12 EP300 ZNF766 POLR2A KDM4B AFF1 NCOR1 MIR199A1 MIR6793 TMED1 DNM2 lnc-TIMM29-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6793 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR6793 Gene

Genomic Locations for MIR6793 Gene
chr19:10,828,973-10,829,035
(GRCh38/hg38)
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR6793 Gene

Genes around MIR6793 on UCSC Golden Path with GeneCards custom track
MIR6793 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR6793 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6793 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6793 Gene

Proteins for MIR6793 Gene

Post-translational modifications for MIR6793 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6793 Gene

Domains & Families for MIR6793 Gene

Gene Families for MIR6793 Gene

HGNC:
genes like me logo Genes that share domains with MIR6793: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR6793 Gene

Function for MIR6793 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6793 Gene

Localization for MIR6793 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6793 Gene

Pathways & Interactions for MIR6793 Gene

PathCards logo

SuperPathways for MIR6793 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR6793 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR6793 Gene

Drugs & Compounds for MIR6793 Gene

No Compound Related Data Available

Transcripts for MIR6793 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR6793 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000075BB5A_9606 precursor_RNA 63 4

HGNC: 50251,

RefSeq: NR_106851,

Ensembl: ENST00000612376 (view in UCSC) ,

miRBase: MI0022638,

URS000075C6F8_9606 miRNA 22 2

RefSeq: NR_106851,

miRBase: MIMAT0027486,

URS000075EFC6_9606 miRNA 20 2

RefSeq: NR_106851,

miRBase: MIMAT0027487,

MIR6793 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6793 Gene

No ASD Table

Relevant External Links for MIR6793 Gene

GeneLoc Exon Structure for
MIR6793

No data available for mRNA/cDNA for MIR6793 Gene

Expression for MIR6793 Gene

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6793 Gene

Orthologs for MIR6793 Gene

Evolution for MIR6793 Gene

ENSEMBL:
Gene Tree for MIR6793 (if available)
TreeFam:
Gene Tree for MIR6793 (if available)

No data available for Orthologs for MIR6793 Gene

Paralogs for MIR6793 Gene

No data available for Paralogs for MIR6793 Gene

Variants for MIR6793 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MIR6793 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs377150057 Benign/Likely Benign: Charcot-Marie-Tooth disease, dominant intermediate B; not specified 10,829,031(+) C/T NON_CODING_TRANSCRIPT_VARIANT,INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for MIR6793 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR6793 Gene

Variant ID Type Subtype PubMed ID
nsv1160584 CNV deletion 26073780
nsv2416 CNV insertion 18451855
nsv833746 CNV loss 17160897
nsv833748 CNV loss 17160897

Additional Variant Information for MIR6793 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6793

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6793 Gene

Disorders for MIR6793 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MIR6793 Gene - From: GeneCards

Disorder Aliases PubMed IDs
charcot-marie-tooth disease, dominant intermediate b
  • cmtdib
charcot-marie-tooth disease
  • peroneal muscular atrophy
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6793

genes like me logo Genes that share disorders with MIR6793: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6793 Gene

Publications for MIR6793 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3

Products for MIR6793 Gene

Sources for MIR6793 Gene