Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR6793 Gene

Subcategory (RNA class) for MIR6793 Gene

miRNA

Quality Score for this RNA gene is

13

Aliases for MIR6793 Gene

  • MicroRNA 6793 2 3 5
  • MicroRNA Mir-6793 3
  • Hsa-Mir-6793 3

External Ids for MIR6793 Gene

Previous GeneCards Identifiers for MIR6793 Gene

  • GC19U901786

Summaries for MIR6793 Gene

Entrez Gene Summary for MIR6793 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR6793 Gene

MIR6793 (MicroRNA 6793) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR6793 include Dnm2-Related Intermediate Charcot-Marie-Tooth Neuropathy.

Additional gene information for MIR6793 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR6793 Gene

Genomics for MIR6793 Gene

GeneHancer (GH) Regulatory Elements for MIR6793 Gene

Promoters and enhancers for MIR6793 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J010830 Enhancer 0.6 ENCODE 600.7 +0.2 247 0.2 MLLT1 ZBTB33 ZNF600 ZIC2 ATF1 CTCF SCRT2 CREM HIC1 MIR6793 ILF3 TMED1 DNM2
GH19J010829 Enhancer 0.5 ENCODE 600.7 +0.4 424 0 ZIC2 ATF1 CTCF SCRT2 HIC1 ZBTB33 MIR6793 ILF3 TMED1 DNM2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR6793 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR6793 Gene

Genomic Locations for MIR6793 Gene
chr19:10,828,973-10,829,035
(GRCh38/hg38)
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR6793 Gene

Genes around MIR6793 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR6793 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR6793 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR6793 Gene

Proteins for MIR6793 Gene

Post-translational modifications for MIR6793 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR6793 Gene

Domains & Families for MIR6793 Gene

Gene Families for MIR6793 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR6793: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR6793 Gene

Function for MIR6793 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR6793 Gene

Localization for MIR6793 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR6793 Gene

Pathways & Interactions for MIR6793 Gene

PathCards logo

SuperPathways for MIR6793 Gene

No Data Available

Interacting Proteins for MIR6793 Gene

Gene Ontology (GO) - Biological Process for MIR6793 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR6793 Gene

Drugs & Compounds for MIR6793 Gene

No Compound Related Data Available

Transcripts for MIR6793 Gene

mRNA/cDNA for MIR6793 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR6793 Gene

No ASD Table

Relevant External Links for MIR6793 Gene

GeneLoc Exon Structure for
MIR6793
ECgene alternative splicing isoforms for
MIR6793

Expression for MIR6793 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR6793 Gene:

MIR6793
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR6793 Gene

Orthologs for MIR6793 Gene

Evolution for MIR6793 Gene

ENSEMBL:
Gene Tree for MIR6793 (if available)
TreeFam:
Gene Tree for MIR6793 (if available)

No data available for Orthologs for MIR6793 Gene

Paralogs for MIR6793 Gene

No data available for Paralogs for MIR6793 Gene

Variants for MIR6793 Gene

Sequence variations from dbSNP and Humsavar for MIR6793 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs117598326 benign, likely-benign, DNM2-related intermediate Charcot-Marie-Tooth neuropathy, not specified, Centronuclear Myopathy, Dominant, Charcot-Marie-Tooth, Intermediate 10,829,137(+) C/T downstream_transcript_variant
rs142963320 uncertain-significance, Charcot-Marie-Tooth, Intermediate, Centronuclear Myopathy, Dominant, DNM2-related intermediate Charcot-Marie-Tooth neuropathy 10,829,156(+) C/T downstream_transcript_variant
rs149164657 likely-benign, benign-likely-benign, benign, Charcot-Marie-Tooth, Intermediate, Centronuclear Myopathy, Dominant, not specified, DNM2-related intermediate Charcot-Marie-Tooth neuropathy 10,829,038(+) G/A/T downstream_transcript_variant
rs1555716924 likely-benign, DNM2-related intermediate Charcot-Marie-Tooth neuropathy 10,829,113(+) G/T downstream_transcript_variant
rs2229920 benign-likely-benign, benign, not specified, Centronuclear Myopathy, Dominant, Charcot-Marie-Tooth, Intermediate 10,829,116(+) T/C/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR6793 Gene

Variant ID Type Subtype PubMed ID
nsv1160584 CNV deletion 26073780
nsv2416 CNV insertion 18451855
nsv833746 CNV loss 17160897
nsv833748 CNV loss 17160897

Additional Variant Information for MIR6793 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR6793

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR6793 Gene

Disorders for MIR6793 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR6793 Gene - From: GeneCards

Disorder Aliases PubMed IDs
dnm2-related intermediate charcot-marie-tooth neuropathy
  • charcot-marie-tooth disease, dominant intermediate b
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR6793

genes like me logo Genes that share disorders with MIR6793: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR6793 Gene

Publications for MIR6793 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR6793 Gene

Sources for MIR6793 Gene

Content
Loading form....